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Research Articles

Identification and characterization of glucocorticoid receptor-binding sites in the human genome

, , , , , , & show all
Pages 88-105 | Received 17 Dec 2009, Accepted 06 Jan 2010, Published online: 18 Feb 2010

References

  • Kumar R, Thompson EB. Gene regulation by the glucocorticoid receptor: structure:function relationship.J Steroid Biochem Mol Biol 2005;94:383–94.
  • Phuc Le P, Friedman JR, Schug J, et al. Glucocorticoid receptor-dependent gene regulatory networks. PLoS Genet 2005;1:e16.
  • Wang JC, Derynck MK, Nonaka DF, Khodabakhsh DB, Haqq C, Yamamoto KR. Chromatin immunoprecipitation (ChIP) scanning identifies primary glucocorticoid receptor target genes. Proc Natl Acad Sci USA 2004;101:15603–8.
  • So AY, Chaivorapol C, Bolton EC, Li H, Yamamoto KR. Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor. PLoS Genet 2007;3:e94.
  • Chorley BN, Wang X, Campbell MR, et al. Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: current and developing technologies. Mutat Res 2008;659:147–57.
  • Chang LW, Nagarajan R, Magee JA, Milbrandt J, Stormo GD. A systematic model to predict transcriptional regulatory mechanisms based on overrepresentation of transcription factor binding profiles. Genome Res 2006;16:405–13.
  • Deplancke B, Dupuy D, Vidal M, Walhout AJ. A gateway-compatible yeast one-hybrid system. Genome Res 2004;14:2093–101.
  • Vidal M, Brachmann RK, Fattaey A, Harlow E, Boeke JD. Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions. Proc Natl Acad Sci USA 1996;93:10315–20.
  • Farnham PJ. Insights from genomic profiling of transcription factors. Nat Rev Genet 2009;10:605–16.
  • Wells J, Yan PS, Cechvala M, Huang T, Farnham PJ. Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase. Oncogene 2003;22:1445–60.
  • Dostert A, Heinzel T. Negative glucocorticoid receptor response elements and their role in glucocorticoid action. Curr Pharm Des 2004;10:2807–16.
  • Ponomarenko JV, Orlova GV, Merkulova TI, et al. rSNP_Guide: an integrated database-tools system for studying SNPs and site-directed mutations in transcription factor binding sites. Hum Mutat 2002;20:239–48.
  • Yanai K, Saito T, Hirota K, et al. Molecular variation of the human angiotensinogen core promoter element located between the TATA box and transcription initiation site affects its transcriptional activity. J Biol Chem 1997;272:30558–62.
  • Ono S, Ezura Y, Emi M, et al. A promoter SNP (-1323T>C) in G-substrate gene (GSBS) correlates with hypercholesterolemia. J Hum Genet 2003;48:447–50.
  • Kashtan CE. Alport syndrome. An inherited disorder of renal, ocular, and cochlear basement membranes. Medicine (Baltimore) 1999;78:338–60.
  • Tarshish P, Tobin JN, Bernstein J, Edelmann CM Jr. Prognostic significance of the early course of minimal change nephrotic syndrome: report of the International Study of Kidney Disease in Children. J Am Soc Nephrol 1997;8:769–76.
  • Ford DM, Briscoe DM, Shanley PF, Lum GM. Childhood membranoproliferative glomerulonephritis type I: limited steroid therapy. Kidney Int 1992;41:1606–12.
  • Kobayashi Y, Fujii K, Hiki Y, Tateno S, Kurokawa A, Kamiyama M. Steroid therapy in IgA nephropathy: a retrospective study in heavy proteinuric cases. Nephron 1988;48:12–17.
  • Reddy TE, Pauli F, Sprouse RO, et al. Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation. Genome Res 2009;19:2163–71.

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