13
Views
10
CrossRef citations to date
0
Altmetric
Research Article

Some Unique Properties of CGP-12177

, , &
Pages 103-111 | Published online: 26 Sep 2008

References

  • Staehelin M., Simons P., Jaeegi K., Wigger N. CGP-12177: A hydrophilic beta-adrenergic receptor radioligand reveals high affinity binding of agonists to intact cells. J. Biol. Chem. 1983; 258: 3496–3502
  • Staehelin M., Hertel C. [3H]CGP-12177, a β-adrenergic ligand suitable for measuring cell surface receptors. J. Rec. Res. 1983; 3: 35–43
  • Hertel C., Mueller P., Portenier M., Staehelin M. Determination of desensitization of beta-adrenergic receptors by [3H]CGP-12177. Biochem. J. 1983; 216: 669–674
  • Harden T. K., Cotton C. U., Waldo G. L., Lutton J. K., Perkins J. P. Catecholamine-induced alteration in the sedimentation behaviour of membrane-bound beta-adrenergic receptors. Science 1980; 210: 441–443
  • Salomon Y., Londos C., Rodbell M. A Highly sensitive adenylate cyclase assay. Anal. Biochem. 1974; 58: 541–548
  • Hertel C., Staehelin M., Perkins J. P. Evidence for intracellular beta-adrenergic receptors in membrane fractions from desensitized cells: Binding of the hydrophilic ligand CGP-12177 only in the presence of alamethicin. J. Cyclic. Nucleotide and Protein Phosphoryl. Res. 1983; 9: 119–128
  • Insel P. A., Sanda M. Temperature-dependent changes in binding to β-adrenergic receptors of intact S49 lymphoma cells. J. Biol. Chem. 1979; 254: 6554–6559
  • Haga T., Ross E. M., Anderson H. J., Gilman A. G. Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells. Proc. Natl. Acad. Sci. USA 1977; 74: 2016–2020
  • Ross E. M., Maguire M. E., Sturgill T. W., Biltonen R. L., Gilman A. G. Relationship between the β-adrenergic receptor and adenylate cyclase. J. Biol. Chem. 1977; 252: 5761–5775

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.