Treatment with Antisense Oligodeoxynucleotide to a Conserved Sequence of Opioid Receptors Inhibits Antinociceptive Effects of Delta Subtype Selective Ligands

References

• Mosberg H. I., Hurst R., Hruby V. J., Gee K., Yamamura H. I., Galligan J. J., Burks T. F. Bis-penicillamine enkephalins show pronounced δ opioid receptor selectivity. Proc. Natl. Acad. Sci. U.S.A. 1983; 80: 5871–5874
   PubMed Web of Science ®Google Scholar
• Erspamer V., Melchiorri P., Falconieri-Erspamer G., Negri L., Corsi R., Severini C., Barra D., Simmaco M., Kreil G. Deltorphins: a family of naturally occurring peptides with high affinity and selectivity for S opioid binding sites. Proc. Natl. Acad. Sci. U.S.A. 1989; 86: 5188–5192
   PubMed Web of Science ®Google Scholar
• Bowen W. D., Hellewell S. B., Kelemen M., Huey R., Stewart D. Affinity labeling of δ-opiate receptors using [D-Ala2, Len5, Cys6]enkephalin: Covalent attachment via thiol-disulfide exchange. J. Biol. Chem. 1987; 262: 13434–13439
   Google Scholar
• Jiang Q., Takemori A. E., Sultana M., Portoghese P. S., Bowen W. D., Mosberg H. I., Porreca F. Differential antagonism of opioid δ agonist effects by [DAla2, Leu5, Cys6]enkephalin (DALCE) and naltrindole 5′-isothiocyanate (NTII): evidence for δ receptor subtypes. J. Pharmacol. Exp. Ther. 1991; 257: 1069–1075
   PubMed Web of Science ®Google Scholar
• Portoghese P. S., Sultana M., Takemori A. E. Naltrindole 5′-isothiocyanate: a nonequilibrium. highly selective δ opioid receptor antagonist, J. Med. Chem. 1990; 33: 1547–1548
   PubMed Web of Science ®Google Scholar
• Mattia A., Vanderah T., Mosberg H. I., Porreca F. Lack of antinociceptive cross-tolerance between [D-Pen2, D-Pen5]enkephalin and [D-Ala2]deltorphin II in mice; evidence for delta opioid receptor subtypes. J. Phannacol. Exp. Ther. 1991; 258: 583–587
   PubMed Web of Science ®Google Scholar
• Sofuoglu M., Portoghese P. S., Takemori A. E. Differential antagonism of delta opioid agonists by naltrindole and its benzofuran analog (NTB) in mice: evidence for delta opioid receptor subtypes. J. Pharmacol. Exp. Ther. 1991; 257: 676–680
   PubMed Web of Science ®Google Scholar
• Buzas B., Izenwasser S., Portoghese P. S., Cox B. M. Evidence for delta opioid receptor subtypes regulating adenylyl cyclase activity in rat brain. Life Sci. Pharmacol. Lett. 1994; 54: PL101–106
   Google Scholar
• Portoghese P. S., Sultana M., Nagase H., Takemori A. E. δ-opioid receptor binding in mouse brain: evidence for heterogeneous binding sites. Eur. J. Pharmacol. 1992; 218: 195–196
   PubMed Web of Science ®Google Scholar
• Xu H., Partilla J. S., De Costa B. R., Rice K. C., Rothman R. B. Preliminary ligand binding data for subtypes of the delta opioid receptor in rat brain membranes. Peptides 1993; 14: 893–907
   Google Scholar
• Wild K. D., Bilsky E. J., Wild S. L., Yamamura H. I., Beckman A. L., Porreca F. ³H]Naltrindole labels opioid delta receptor subtypes in the ground squirrel hibernator Citellus lateralis 1994, submitted
   Google Scholar
• Evans C. J., Keith D. E., Jr., Morrison H., Magendzo K., Edwards R. H. Cloning of a delta opioid receptor by functional expression. Science 1992; 258: 1952–1955
   PubMed Web of Science ®Google Scholar
• Kieffer B. L., Befort K., Gaveriaux-Ruff C., Hirth C. G. The delta opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proc. Natl. Acad. Sci. 1992; 89: 12048–12052
   PubMed Web of Science ®Google Scholar
• Wahlestedt C., Pich E. M., Koog G. F., Yee F., Heilig M. Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides. Science 1993; 259: 528–531
   PubMed Web of Science ®Google Scholar
• Lai J., Bilsky E. J., Rothman R. B., Porreca F. Antisense oligodeoxynucleotide to the cloned opioid delta receptor selectively inhibits antinociception of a delta2-opioid agonist. NeuroReport. 1994, in press
   Google Scholar
• Bilsky E. J., Bernstein R. N., Pasternak G. W., Hruby V. J., Patel D., Porreca F., Lai J. Selective inhibition of [D-Ala2, Glu4]deltorphin antinociception by supraspinal, but not spinal, administration of an antisense oligodeoxynucleotide to an opioid delta receptor. Life Sci. Pharmacol. Lett. 1994, in press
   Google Scholar
• Yasuda K., Raynor K., Kong H., Breder C., Takeda J., Reisine T., Bell G. I. Cloning and functional comparison of kappa and delta opioid receptors from mouse brain. Proc. Natl. Acad. Sci. (U.S.A.) 1993; 90: 6736–6740
   PubMed Web of Science ®Google Scholar
• Chen Y., Mesick A., Liu J., Hurley A., Yu L. Molecular cloning and functional expression of a mu opioid receptor from rat brain. Mol. Pharmacol. 1993; 44: 8–12
   PubMed Web of Science ®Google Scholar
• Jiang Q., Mosberg H. I, Porreca F. Antinociceptive effects of [DAla2]deltorphin II, a highly selective δ agonist in vivo. Life Sci. Pharmacol. Lett. 1990; 47: PL43–PL47
   Google Scholar