References
- Cai BC, Wu H, Yang XW, Hattori M, Nainba T. Analysis of spectral data for 13CNMR of sixteen strychnos alkaloids. Yao Xue Xue Bao 1994;29:44.
- Cai BC, Wang TS, Kurokawa M, Shiraki K, Hattori M. Cytotoxicities of alkaloids from processed and unprocessed seeds of Strychnos nux-vomica. Zhongguo Yao Li Xue Bao 1998;19:425–428.
- Deng XK, Yin W, Li WD, Yin FZ, Lu XY, Zhang XC et al. The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism. j Ethnopharmacol 2006;106:179–186.
- Deng X, Yin F, Lu X, Cai B, Yin W. The apoptotic effect of brucine from the seed of Strychnos nux-vomica on human hepatoma cells is mediated via Bcl-2 and Ca2+ involved mitochondrial pathway. Toxicol Sci 2006;91:59–69.
- Yin W, Deng XK, Yin FZ, Zhang XC, Cai BC. The cytotoxicity induced by brucine from the seed of Strychnos nux-vomica proceeds via apoptosis and is mediated by cyclooxygenase 2 and caspase 3 in SMMC 7221 cells. Food Chem Toxicol 2007;45:1700–1708.
- Malone MH, St John-Allan KM, Bejar E. Brucine lethality in mice. j Ethnopharmacol 1992;35:295–297.
- Samad A, Sultana Y, Aqil M. Liposomal drug delivery systems: an update review. Curr Drug Deliv 2007;4:297–305.
- Cattel L, Ceruti M, Dosio F. From conventional to stealth liposomes: a new frontier in cancer chemotherapy. Tumori 2003;89:237–249.
- Chen J, Lin A, Chen Z, Wang W, Zhang T, Cai H et al. Ammonium sulfate gradient loading of brucine into liposomes: effect of phospholipid composition on entrapment efficiency and physicochemical properties in vitro. Drug Dev Ind Pharm 2010;36:245–253.
- Haran G, Cohen R, Bar LK, Barenholz Y. Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim Biophys Acta 1993;1151:201–215.
- Qin XQ, Yuan Y, Liu CS, Wang QY, Shen X, Yang BC. Preparation of liposomal brucine and its pharmaceutical/pharmacodynamic characterization. Acta Pharmacol Sin 2007;28:1851–1858.
- Li C, Cui J, Wang C, Wang J, Li Y, Zhang L et al. Lipid composition and grafted PEG affect in vivo activity of liposomal mitoxantrone. Int j Pharm 2008;362:60–66.
- Drummond DC, Meyer O, Hong K, Kirpotin DB, Papahadjopoulos D. Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors. Pharmacol Rev 1999;51:691–743.