255
Views
12
CrossRef citations to date
0
Altmetric
Research Article

Preparation, characterization and tissue distribution of brucine stealth liposomes with different lipid composition

, , &
Pages 772-778 | Received 20 May 2010, Accepted 20 Sep 2010, Published online: 22 Jul 2011

References

  • Cai BC, Wu H, Yang XW, Hattori M, Nainba T. Analysis of spectral data for 13CNMR of sixteen strychnos alkaloids. Yao Xue Xue Bao 1994;29:44.
  • Cai BC, Wang TS, Kurokawa M, Shiraki K, Hattori M. Cytotoxicities of alkaloids from processed and unprocessed seeds of Strychnos nux-vomica. Zhongguo Yao Li Xue Bao 1998;19:425–428.
  • Deng XK, Yin W, Li WD, Yin FZ, Lu XY, Zhang XC et al. The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism. j Ethnopharmacol 2006;106:179–186.
  • Deng X, Yin F, Lu X, Cai B, Yin W. The apoptotic effect of brucine from the seed of Strychnos nux-vomica on human hepatoma cells is mediated via Bcl-2 and Ca2+ involved mitochondrial pathway. Toxicol Sci 2006;91:59–69.
  • Yin W, Deng XK, Yin FZ, Zhang XC, Cai BC. The cytotoxicity induced by brucine from the seed of Strychnos nux-vomica proceeds via apoptosis and is mediated by cyclooxygenase 2 and caspase 3 in SMMC 7221 cells. Food Chem Toxicol 2007;45:1700–1708.
  • Malone MH, St John-Allan KM, Bejar E. Brucine lethality in mice. j Ethnopharmacol 1992;35:295–297.
  • Samad A, Sultana Y, Aqil M. Liposomal drug delivery systems: an update review. Curr Drug Deliv 2007;4:297–305.
  • Cattel L, Ceruti M, Dosio F. From conventional to stealth liposomes: a new frontier in cancer chemotherapy. Tumori 2003;89:237–249.
  • Chen J, Lin A, Chen Z, Wang W, Zhang T, Cai H et al. Ammonium sulfate gradient loading of brucine into liposomes: effect of phospholipid composition on entrapment efficiency and physicochemical properties in vitro. Drug Dev Ind Pharm 2010;36:245–253.
  • Haran G, Cohen R, Bar LK, Barenholz Y. Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim Biophys Acta 1993;1151:201–215.
  • Qin XQ, Yuan Y, Liu CS, Wang QY, Shen X, Yang BC. Preparation of liposomal brucine and its pharmaceutical/pharmacodynamic characterization. Acta Pharmacol Sin 2007;28:1851–1858.
  • Li C, Cui J, Wang C, Wang J, Li Y, Zhang L et al. Lipid composition and grafted PEG affect in vivo activity of liposomal mitoxantrone. Int j Pharm 2008;362:60–66.
  • Drummond DC, Meyer O, Hong K, Kirpotin DB, Papahadjopoulos D. Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors. Pharmacol Rev 1999;51:691–743.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.