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Research Article

Development and optimization of lyophilized orally disintegrating tablets using factorial design

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Pages 935-943 | Received 16 Jun 2011, Accepted 24 Aug 2011, Published online: 22 Nov 2011

References

  • Ciper M, Bodmeier R. Modified conventional hard gelatin capsules as fast disintegrating dosage form in the oral cavity. Eur J Pharm Biopharm 2006;62:178–184.
  • Mizumoto T, Masuda Y, Yamamoto T, Yonemochi E, Terada K. Formulation design of a novel fast-disintegrating tablet. Int J Pharm 2005;306:83–90.
  • Maya MT, Goncalves NJ, Silva NE, Filipe AE, Morais JA, Caturla MC et al. Comparative bioavailability of two immediate release tablets of enalapril/hydrochlorothiazide in healthy volunteers. Eur J Drug Metab Pharmacokinet 2002;27:91–99.
  • Lohitnavy M, Lohitnavy O, Wittaya-areekul S, Sareekan K, Polnok S, Chaiyaput W. Average bioequivalence of clarithromycin immediate released tablet formulations in healthy male volunteers. Drug Dev Ind Pharm 2003;29:653–659.
  • Carpay J, Schoenen J, Ahmad F, Kinrade F, Boswell D. Efficacy and tolerability of sumatriptan tablets in a fast-disintegrating, rapid-release formulation for the acute treatment of migraine: results of a multicenter, randomized, placebo-controlled study. Clin Ther 2004;26:214–223.
  • Papadimitriou E, Efantakis M, Choulis NH. Evaluation of maltodextrins as excipients for direct compression tablets and their influence on the rate of dissolution. Int J Pharm 1992;86:131–136.
  • Corveleyn S, Remon JP. Formulation and production of rapidly disintegrating tablets by lyophilization using hydrochlorothiazide as a model drug. Int J Pharm 1997;152:215–225.
  • Corveleyn S, Remon JP. Formulation of a lyophilized dry emulsion tablet for the delivery of poorly soluble drugs. Int J Pharm 1998;166:65–74.
  • Vennat B, Gross D, Pourrat A, Legret P. [Oral freeze-dried forms of procyanidins]. J Pharm Belg 1993;48:430–436.
  • Shoukri RA, Ahmed IS, Shamma RN. In vitro and in vivo evaluation of nimesulide lyophilized orally disintegrating tablets. Eur J Pharm Biopharm 2009;73:162–171.
  • European Pharmacopoeia fourth ed., Suppl. 4.1. Published by the directorate for the quality of medicines of the council of Europe 9EDQM, Strasbourg, France, 2002b.
  • Abdelbary G, Eouani C, Prinderre P, Joachim J, Reynier J, Piccerelle P. Determination of the in vitro disintegration profile of rapidly disintegrating tablets and correlation with oral disintegration. Int J Pharm 2005;292:29–41.
  • Furlanetto S, Maestrelli F, Orlandini S, Pinzauti S, Mura P. Optimization of dissolution test precision for a ketoprofen oral extended-release product. J Pharm Biomed Anal 2003;32:159–165.
  • Furlanetto S, Cirri M, Maestrelli F, Corti G, Mura P. Study of formulation variables influencing the drug release rate from matrix tablets by experimental design. Eur J Pharm Biopharm 2006;62:77–84.
  • `Dekeyser PM, Corveleyn S, Demeester J, Remon JP. Stabilization of fully active chymopapain by lyophilization. Int J Pharm 1997;159:19–25.
  • Mollan MJ, Celik M. Characterization of directly compressible maltodextrins manufactured by three different processes. Drug Dev Ind Pharm 1993;19:2335–2358.
  • Mollan MJ, Celik M. Tabletability of maltodextrin and acetaminophen mixtures. Drug Dev Ind Pharm 1994;20:3131–3149.
  • Dobetti L. Fast-Melting Tablets: Developments and Technologies. Pharm Technol 2001;25:44–50.
  • Kuno Y, Kojima M, Ando S, Nakagami H. Evaluation of rapidly disintegrating tablets manufactured by phase transition of sugar alcohols. J Control Release 2005;105:16–22.
  • Buchi Nalluri N, Chowdary KPR, Murthy KVR, Becket G, Peter Crooks A. Tablet formulation studies on nimesulide and meloxicam − cyclodextrin binary systems. AAPS Pharm Sci Tech 2007;8, Article 36.

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