References
- Gao S, Frederik DH, Ebbe JBN, et al. The effect of chemical modification and nanoparticle formulation on stability and diodistribution of siRNA in mice. Mol Ther 2009;17:1225–33
- Acharya S, Sahoo SK. PLGA nanoparticles containing various anticancer agents and tumor delivery by EPR effect. Adv Drug Del Rev 2011;63:170–83
- Avnesh K, Yadav SK, Yadav SC. Biodegradable polymeric nanoparticles based drug delivery systems. Colloids Surf B Biointerfaces 2010;75:1–18
- Fessi H, Puisieux F, Devissaguet JP, et al. Nanocapsule formation by interfacial deposition following solvent displacement. Int J Pharm 1989;55:R1–4
- Jain SP, Shah S, Rajadhyaksha N, et al. Twice a day ocular inserts of acyclovir by melt extrusion technique. Ind J Pharm Sci 2007;69:562–7
- David B, Hermione L, Leena M. Oral acyclovir suppression after neonatal herpes. N Engl J Med 2012;366:90–1
- Miranda P, Blum MR. Pharmacokinetics of Acyclovir after intravenous and oral administration. J Antimicrob Chemother 1983;12:29–37
- Kamel AO, Awad GA, Geneidi AS, Mortada ND. Preparation and characterization of acyclovir nanoparticles by double emulsion technique. Egy J Biomed Sci 2007;23:218–36
- Claudia G, Claudio B, Adriana M, et al. Influence of preparation conditions on acyclovir-loaded poly-d,l-lactic acid nanospheres and effect of PEG coating on ocular drug bioavailability. Pharm Res 2003;20:584–90
- Ugo B, Eric A, Eric D. Development of a nanoprecipitation method intended for the entrapment of hydrophilic drugs into nanoparticles. Eur J Pharm Sci 2005;24:67–75
- Amany OK, Gehanne ASA, Ahmed SG, Nahed DM. Preparation of intravenous stealthy acyclovir nanoparticles with increased mean residence time. AAPS PharmSciTech 2009;10:1427–36
- Hao J, Xinsheng F, Yanfang Z, et al. Development and optimization of solid lipid nanoparticle formulation for ophthalmic delivery of chloramphenicol using a Box-Behnken design. Int J Nanomed 2011;6:683–92
- Mira EG, Egea1 MA, Souto EB, et al. Optimizing flurbiprofen-loaded NLC by central composite factorial design for ocular delivery. Nanotechnology 2011;22:0957--4484
- Sanjay S, Madaswamy SM. Preparation and characterization of nanoparticles containing an atypical antipsychotic agent. Nanomedicine 2007;2:233–40
- Stephanie S, Joseph TD, Ulrich SS. Nanoprecipitation and nanoformulation of polymers: from history to powerful possibilities beyond poly(lactic acid). Soft Matter 2011;7:1581–8
- Reis PC, Neufeld RJ, Ribeiro AJ, Viega F. Design of insulin loaded alginate nanoparticles: influence of the calcium ion on polymer gel matrix properties. Chem Ind Chem Eng Quart 2006;12:47–52
- Reddy LH, Murthy RSR. Pharmacokinetics and biodistribution studies of doxorubicin loaded poly(butylcyanoacrylate) nanoparticles synthesized by two different techniques. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2004;148:161–6
- Tahereh SJK, Solmaz E, Mehdi EM, et al. Improved drug loading and antibacterial activity of minocycline-loaded PLGA nanoparticles prepared by solid/oil/water ion pairing method. Int J Nanomed 2012;7:221–34
- Lv QZ, Yu AH, Xi YW, et al. Development and evaluation of penciclovir loaded solid lipid nanoparticles for topical delivery. Int J Pharm 2009;372:191–8
- Wang JL, Wang R, Li LB. Preparation and properties of hydroxycamptothecin-loaded nanoparticles made of amphiphilic copolymer and normal polymer. J Colloid Interface Sci 2009;336:808–13
- Bolton S. Pharmaceutical statistics. 3rd ed. New York: Marcel Dekker Inc;1990:326–54
- Montgomery DC. Design and analysis of experiments. 5th ed. New York, NY: Wiley & Sons; 2001
- Roberta C, Manuela D, Andrea C, et al. Enhanced antiviral activity of Acyclovir loaded into β-cyclodextrin-poly(4-acryloylmorpholine) conjugate nanoparticles. J Control Rel 2009;137:116–22
- Amra H, Martin Z, Gottfried R, Claudia V. Chitosan-tripolyphosphate nanoparticles as a possible skin drug delivery system for acyclovir with enhanced stability. J Pharm Pharmacol 2009;61:1609–16
- Kakran M, Sahoo NG, Li L, Judeh Z. Dissolution of artemisinin/polymer composite nanoparticles fabricated by evaporative precipitation of nanosuspension. J Pharm Pharmacol 2010;62:413–21
- Zhang Y, Huo M, Zhou J, et al. DDSolver: an add-in program for modeling and comparison of drug dissolution profiles. AAPS J 2010;12:263–71
- Musumeci T, Ventura CA, Giannone I, et al. PLA/PLGA nanoparticles for sustained release of docetaxel. Int J Pharm 2006;325:172–9
- Witschi C, Doelker E. Influence of the microencapsulation method and peptide loading on poly(lactic acid) and poly(lactic-co-glycolic acid) degradation during in vitro testing. J Control Release 1998;51:327–341
- Lamprecht A, Ubrich N, Hombreiro PM, et al. Influences of process parameters on nanoparticle preparation performed by a double emission pressure homogenization technique. Int J Pharm 2000;196:177–82
- Uchida T, Yoshida K, Nakada Y. Preparation and characterization of polylactic acid microspheres containing water-soluble anesthetics with small molecular weight. Chem Pharm Bull 1997;45:513–17
- Freytag T, Dashevsky A, Tillman L, et al. Improvement of the encapsulation efficiency of oligonucleotide-containing biodegradable microspheres. J Control Release 2000;69:197–207
- Han K, Lee KD, Gao ZG, Park JS. Preparation and evaluation of poly(L-lactic acid) microspheres containing rhEGF for chronic gastric ulcer healing. J Control Release 2001;75:259–69
- Leena P, Johanna A, Samuli H, et al. Improved entrapment efficiency of hydrophilic drug substance during nanoprecipitation of poly(l) lactide nanoparticles. AAPS PharmSciTech 2004;5:1–6
- Govender T, Stolnik S, Garnett MC, et al. PLGA nanoparticles prepared by nanoprecipitation drug loading and release studies of water soluble drug. J Control Release 1999;57:171–85
- Sullivan CO, Birkinshaw C. In vitro degradation of insulin-loaded poly(n-butylcyanoacrylate) nanoparticles. Biomaterials 2004;25:4375–82
- Simeonova M, Ivanova G, Enchev V, et al. Physicochemical characterization and in vitro behavior of daunorubicin-loaded poly(butylcyanoacrylate) nanoparticles. Acta Biomater 2009;5:2109–21
- Duan JH, Zhang YD, Chen W, et al. Cationic polybutyl cyanoacrylate nanoparticles for DNA delivery. J Biomed Biotechnol 2009;149:254–62
- Mayer BX, Mensik C, Krishnaswami S, et al. Pharmacokinetic-pharmacodynamic profile of systemic nitric oxide-synthase inhibition with L-NMMA in humans. Br J Clin Pharmacol 1999;47:539–44