329
Views
28
CrossRef citations to date
0
Altmetric
Research Article

In vitro cytotoxicity and bioavailability of solid lipid nanoparticles containing tamoxifen citrate

, &
Pages 824-832 | Received 01 May 2013, Accepted 12 Aug 2013, Published online: 13 Sep 2013

References

  • Gao S, Singh J. In vitro percutaneous absorption enhancement of a lipophilic drug tamoxifen by terpenes. J Control Rel 1998;51:193–199
  • Bonneterre J, Thurlimann B, Robertson JF, et al. Anastrozole versus tamoxifen as first-line therapy for advanced breast cancer in 668 postmenopausal women: results of the Tamoxifen or arimidex randomized group efficacy and tolerability study. J Clin Oncol 2000;18:3748–3757
  • Cameron DA, Ritchie AA, Langdon S, et al. Tamoxifen induced apoptosis in ZR-75 breast cancer xenografts antedates tumour regression. Breast Cancer Res Treat 1997;45:99–107
  • Chawla JS, Amiji MM. Cellular uptake and concentrations of tamoxifen upon administration in poly (ε-caprolactone) nanoparticles. AAPS PharmSci 2003;5:E3
  • Tukker JJ, Blankenstein MA, Nortier JW. Comparison of bioavailability in man of tamoxifen after oral and rectal administration. J Pharm Pharmacol 1986;38:888–892
  • Bonferoni MC, Rossi S, Ferrari F, et al. Factorial analysis of the influence of dissolution medium on drug release from carrageenan-diltiazem complexes. AAPS PharmSciTech 2000;1:E15
  • Hardman J, Limbird L, Gilman A. The pharmacological basis of therapeutics. 10th ed. NewYork, USA: McGraw-Hill; 2006
  • Shin SC, Choi JS, Li X. Enhanced bioavailability of tamoxifen after oral administration of tamoxifen with quercetin in rats. Int J Pharm 2006;313:144–149
  • Chawla JS, Amiji MM. Biodegradable poly (ε-caprolactone) nanoparticles for tumor-targeted delivery of tamoxifen. Int J Pharm. 2002;249:127–138
  • Brigger I, Chaminade P, Marsaud V, et al. Tamoxifen encapsulation within polyethylene glycol-coated nanospheres. A new antiestrogen formulation. Int J Pharm 2001;214:37–42
  • Kapse SV, Gaikwad RV, Samad A, Devarajan PV. Self nanoprecipitating preconcentrate of tamoxifen citrate for enhanced bioavailability. Int J Pharm 2012;429:104–112
  • Hu FX, Neoh KG, Kang ET. Synthesis and in vitro anti-cancer evaluation of tamoxifen-loaded magnetite/PLLA composite nanoparticles. Biomaterials 2006;27:5725–5733
  • Memisoglu-Bilensoy E, Vural I, Bochot A, et al. Tamoxifen citrate loaded amphiphilic beta-cyclodextrin nanoparticles: in vitro characterization and cytotoxicity. J Control Rel 2005;104:489–496
  • Martinez A, Muniz E, Iglesias I, et al. Enhanced preclinical efficacy of tamoxifen developed as alginate-cysteine/disulfide bond reduced albumin nanoparticles. Int J Pharm 2012;436:574–581
  • Yang L, Geng Y, Li H, et al. Enhancement the oral bioavailability of praziquantel by incorporation into solid lipid nanoparticles. Pharmazie 2009;64:86–89
  • Ugazio E, Cavalli R, Gasco MR. Incorporation of cyclosporin A in solid lipid nanoparticles (SLN). Int J Pharm 2002;241:341–344
  • Li H, Zhao X, Ma Y, et al. Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles. J Control Rel 2009;133:238–244
  • Schwarz C, Mehnert W. Solid lipid nanoparticles (SLN) for controlled drug delivery. II. Drug incorporation and physicochemical characterization. J Microencapsul 1999;16:205–213
  • Song CX, Labhasetwar V, Murphy H, et al. Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery. J Control Rel 1997;43:197–212
  • Kingsley JD, Dou H, Morehead J, et al. Nanotechnology: a focus on nanoparticles as a drug delivery system. J Neuroimmune Pharmacol 2006;1:340–350
  • Wang W, Zhu R, Xie Q, et al. Enhanced bioavailability and efficiency of curcumin for the treatment of asthma by its formulation in solid lipid nanoparticles. Int J Nanomedicine 2012;7:3667–3677
  • Patel BD, Modi RV, Thakkar NA, et al. Development and characterization of solid lipid nanoparticles for enhancement of oral bioavailability of Raloxifene. J Pharm Bioallied Sci 2012;4:S14–16
  • Neves AR, Lucio M, Martins S, et al. Novel resveratrol nanodelivery systems based on lipid nanoparticles to enhance its oral bioavailability. Int J Nanomedicine 2013;8:177–187
  • Chalikwar SS, Belgamwar VS, Talele VR, et al. Formulation and evaluation of Nimodipine-loaded solid lipid nanoparticles delivered via lymphatic transport system. Colloids Surf B Biointerfaces 2012;97:109–116
  • Fontana G, Maniscalco L, Schillaci D, et al. Solid lipid nanoparticles containing tamoxifen characterization and in vitro antitumoral activity. Drug Deliv 2005;12:385–392
  • Barbieri S, Sonvico F, Como C, et al. Lecithin/chitosan controlled release nanopreparations of tamoxifen citrate: loading, enzyme-trigger release and cell uptake. J Control Rel 2013;167:276–283
  • Alhaj NA, Abdullah R, Ibrahim S, Bustamam A. Tamoxifen drug loading solid lipid nanoparticles prepared by hot high pressure homogenization techniques. Am J Pharmacol Toxicol 2008;3:219–224
  • Reddy LH, Vivek K, Bakshi N, Murthy RS. Tamoxifen citrate loaded solid lipid nanoparticles (SLN): preparation, characterization, in vitro drug release, and pharmacokinetic evaluation. Pharm Dev Technol 2006;11:167–177
  • Schubert M, Muller-Goymann C. Solvent injection as a new approach for manufacturing lipid nanoparticles–evaluation of the method and process parameters. Eur J Pharm Biopharm 2003;55:125–131
  • Vitorino C, Carvalho FA, Almeida AJ, et al. The size of solid lipid nanoparticles: an interpretation from experimental design. Colloids Surf B Biointerfaces 2011;84:117–130
  • Hu L, Tang X, Cui F. Solid lipid nanoparticles (SLNs) to improve oral bioavailability of poorly soluble drugs. J Pharm Pharmacol 2004;56:1527–1535
  • Ling G, Zhang P, Zhang W, et al. Development of novel self-assembled DS-PLGA hybrid nanoparticles for improving oral bioavailability of vincristine sulfate by P-gp inhibition. J Control Rel 2010;148:241–248
  • Kheradmandnia S, Vasheghani-Farahani E, Nosrati M, Atyabi F. Preparation and characterization of ketoprofen-loaded solid lipid nanoparticles made from beeswax and carnauba wax. Nanomedicine 2010;6:753–759
  • Skehan P, Storeng R, Scudiero D, et al. New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 1990;82:1107–1112
  • Merey HA, Galal MM, Salem MY, Abdel-Moety EM. Chromatographic determination of tamoxifen citrate in presence of some co-administered drugs. J Pharm Res 2011;4:2458–2461
  • Manjunath K, Reddy JS, Venkateswarlu V. Solid lipid nanoparticles as drug delivery systems. Methods Find Exp Clin Pharmacol 2005;27:127–144
  • Leroux JC, Allemann E, Doelker E, Gurny R. New approach for the preparation of nanoparticles by an emulsification–diffusion method. Eur J Pharm Biopharm 1994;41:14–18
  • Villalobos-Hernandez JR, Muller-Goymann CC. Novel nanoparticulate carrier system based on carnauba wax and decyl oleate for the dispersion of inorganic sunscreens in aqueous media. Eur J Pharm Biopharm 2005;60:113–122
  • Pathan IB, Setty M. Enhancement of transdermal delivery of tamoxifen citrate using noanoemulsion vehicle. Int J Pharm Tech Res 2011;3:287–297
  • Doktorovova S, Shegokar R, Rakovsky E, et al. Cationic solid lipid nanoparticles (cSLN): structure, stability and DNA binding capacity correlation studies. Int J Pharm 2011;420:341–349
  • Das S, Ng WK, Kanaujia P, et al. Formulation design, preparation and physicochemical characterizations of solid lipid nanoparticles containing a hydrophobic drug: effects of process variables. Colloids Surf B Biointerfaces 2011;88:483–489
  • Sari A, Akcay M, Soylak M, Onal A. Polymer-stearic acid blends as form-stable phase change material for thermal energy storage. J Sci Indi Res 2005;64:991–996
  • Jagadeesh H, Deviv K. Tamoxifen loaded poly (ε-caprolactone) based injectable microsphers for breast cancer. Int J Pharm Pharm Sci 2010;2:189–195
  • Muller RH, Radtke M, Wissing SA. Nanostructured lipid matrices for improved microencapsulation of drugs. Int J Pharm 2002;242:121–128
  • Abbasalipourkabir R, Salehzadeh A, Abdullah R. Antitumor activity of tamoxifen loaded solid lipid nanoparticles on induced mammary tumor gland in Sprague-Dawley rats. Afr J Biotechnol 2010;9:7337–7345
  • Jain AK, Swarnakar NK, Godugu C, et al. The effect of the oral administration of polymeric nanoparticles on the efficacy and toxicity of tamoxifen. Biomaterials 2011;32:503–515
  • Priano L, Esposti D, Esposti R, et al. Solid lipid nanoparticles incorporating melatonin as new model for sustained oral and transdermal delivery systems. J Nanosci Nanotechnol 2007;7:3596–3601
  • Li H, Zhao X, Ma Y, et al. Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles. J Control Rel 2009;133:238–244
  • Hunt JN, Knox MT. Control of gastric emptying. Am J Dig Dis 1968;13:372–375
  • Norris DA, Puri N, Sinko PJ. The effect of physical barriers and properties on the oral absorption of particulates. Adv Drug Deliv Rev 1998;34:135–154
  • John H, Charlotte J, Jonathan A, et al. Controlled vaccine release in the gut-associated lymphoid tissue, I: orally administered biodegradable microspheres target the Peyer's patches. J Control Rel 1990;11:205–214
  • Bargoni A, Cavalli R, Caputo O, et al. Solid lipid nanoparticles in lymph and plasma after duodenal administration to rats. Pharm Res 1998;15:745–750
  • Hauss DJ, Fogal SE, Ficorilli JV, et al. Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor. J Pharm Sci 1998;87:164–169

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.