Formulation of ciprofloxacin hydrochloride loaded biodegradable nanoparticles: optimization of technique and process variables

References

• WHO C diseases. WHO | Chronic diseases. World Health Organization. Available from: http://www.who.int/topics/chronic_diseases/en/ [last accessed 3 May 2012]
   Google Scholar
• Lew D, Waldvogel F. Osteomyelitis. New Engl J Med 1997;336:999–1007
   PubMed Web of Science ®Google Scholar
• Haidar R, Der Boghossian A, Atiyeh B. Duration of post-surgical antibiotics in chronic osteomyelitis: empiric or evidence-based? Int J Infect Dis 2010;14:e752–e758
   PubMed Web of Science ®Google Scholar
• Sheehy SH, Atkins BA, Bejon P, et al. The microbiology of chronic osteomyelitis: prevalence of resistance to common empirical anti-microbial regimens. J infect 2010;60:338–343
   PubMed Web of Science ®Google Scholar
• Ellington JK, Harris M, Hudson MC, et al. Intracellular Staphylococcus aureus and antibiotic resistance: implications for treatment of staphylococcal osteomyelitis. J Orthop Res 2006;24:87–93
   PubMed Web of Science ®Google Scholar
• Jeong Y-I, Na H-S, Seo D-H, et al. Ciprofloxacin-encapsulated poly(dl-lactide-co-glycolide) nanoparticles and its antibacterial activity. Int J Pharm 2008;352:317–323
   PubMed Web of Science ®Google Scholar
• Nelson JM, Chiller TM, Powers JH, Angulo FJ. Fluoroquinolone-resistant Campylobacter species and the withdrawal of fluoroquinolones from use in poultry: a public health success story. Clin Infect Dis 2007;44:977–980
   PubMed Web of Science ®Google Scholar
• Drlica K, Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev 1997;61:377–392
   PubMed Web of Science ®Google Scholar
• Koort JK, Suokas E, Veiranto M, et al. In vitro and in vivo testing of bioabsorbable antibiotic containing bone filler for osteomyelitis treatment. J Biomed Mater Res A 2006;78:532–540
   PubMed Web of Science ®Google Scholar
• Castro C, Sánchez E, Delgado A, et al. Ciprofloxacin implants for bone infection. In vitro–in vivo characterization. J Control Rel 2003;93:341–354
   PubMed Web of Science ®Google Scholar
• Overbeck JP, Winckler ST, Meffert R, et al. Penetration of ciprofloxacin into bone: a new bioabsorbable implant. J Invest Surg 1995;8:155–162
   PubMed Web of Science ®Google Scholar
• Dimaio FR, O’Halloran JJ, Quale JM. In vitro elution of ciprofloxacin from polymethylmethacrylate cement beads. J Orthop Res 1994;12:79–82
   PubMed Web of Science ®Google Scholar
• Calhoun JH, Manring M. Adult osteomyelitis. Infect Dis Clin N Am 2005;19:765–786
   PubMed Web of Science ®Google Scholar
• Champion JA, Katare YK, Mitragotri S. Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers. J Control Rel 2007;121:3–9
   PubMed Web of Science ®Google Scholar
• Pal SL, Jana U, Manna PK, et al. Nanoparticle: an overview of preparation and characterization. J Appl Pharm Sci 2011;01:228–234
   Google Scholar
• Mundargi RC, Babu VR, Rangaswamy V, et al. Nano/micro technologies for delivering macromolecular therapeutics using poly(d,l-lactide-co-glycolide) and its derivatives. J Control Rel 2008;125:193–209
   PubMed Web of Science ®Google Scholar
• Cevher E, Orhan Z, Sensoy D, et al. Sodium fusidate-poly(d,l-lactide-co-glycolide) microspheres: preparation, characterisation and in vivo evaluation of their effectiveness in the treatment of chronic osteomyelitis. J Microencapsul 2007;24:577–595
   PubMed Web of Science ®Google Scholar
• Prior S, Gander B, Blarer N, et al. In vitro phagocytosis and monocyte-macrophage activation with poly(lactide) and poly(lactide-co-glycolide) microspheres. Eur J Pharm Sci 2002;15:197–207
   PubMed Web of Science ®Google Scholar
• Lecároz C, Blanco-Prieto MJ, Burrell MA, Gamazo C. Intracellular killing of Brucella melitensis in human macrophages with microsphere-encapsulated gentamicin. J Antimicrob Chemother 2006;58:549–556
   PubMed Web of Science ®Google Scholar
• Xu Q, Crossley A, Czernuszka JAN. Preparation and characterization of negatively charged poly (lactic-co-glycolic acid) microspheres. J Pharm Sci 2009;98:2377--2389
   Google Scholar
• Sahoo SK, Panyam J, Prabha S, Labhasetwar V. Residual polyvinyl alcohol associated with poly (d,l-lactide-co-glycolide) nanoparticles affects their physical properties and cellular uptake. J Control Rel 2002;82:105–114
   PubMed Web of Science ®Google Scholar
• Dong Y, Feng S-S. Poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles prepared by high pressure homogenization for paclitaxel chemotherapy. Int J Pharm 2007;342:208–214
   PubMed Web of Science ®Google Scholar
• Dillen K, Vandervoort J, Van den Mooter G, Ludwig A. Evaluation of ciprofloxacin-loaded Eudragit RS100 or RL100/PLGA nanoparticles. Int J Pharm 2006;314:72–82
   PubMed Web of Science ®Google Scholar
• Yu W, Wong J, Chang T. Biodegradable polylactic acid nanocapsules containing ciprofloxacin: preparation and characterization. Artif Cells Blood Substit Immobil Biotechnol 1999;27:263–278
   PubMed Web of Science ®Google Scholar
• Dillen K, Vandervoort J, Van den Mooter G, et al. Factorial design, physicochemical characterisation and activity of ciprofloxacin-PLGA nanoparticles. Int J Pharm 2004;275:171–187
   PubMed Web of Science ®Google Scholar
• Sant S, Nadeau V, Hildgen P. Effect of porosity on the release kinetics of propafenone-loaded PEG-g-PLA nanoparticles. J Control Rel 2005;107:203–214
   PubMed Web of Science ®Google Scholar
• Higuchi T. Rate of release of medicaments from ointment bases containing drugs in suspension. Int J Pharm 1961;50:874–875
   Google Scholar
• Bilati U, Allémann E, Doelker E. Sonication parameters for the preparation of biodegradable nanocapsules of controlled size by the double emulsion method. Pharm Dev Technol 2003;8:1–9
   PubMed Web of Science ®Google Scholar
• Meng FT, Ma GH, Qiu W, Su ZG. W/O/W double emulsion technique using ethyl acetate as organic solvent: effects of its diffusion rate on the characteristics of microparticles. J Control Rel 2003;91:407–416
   PubMed Web of Science ®Google Scholar
• Cohen-Sela E, Chorny M, Koroukhov N, et al. A new double emulsion solvent diffusion technique for encapsulating hydrophilic molecules in PLGA nanoparticles. J Control Rel 2009;133:90–95
   PubMed Web of Science ®Google Scholar
• Lamprecht A, Ubrich N, Pérez MH, et al. Influences of process parameters on nanoparticle preparation performed by a double emulsion pressure homogenization technique. Int J Pharm 2000;196:177–182
   PubMed Web of Science ®Google Scholar
• Li X, Xu Y, Chen G, et al. PLGA nanoparticles for the oral delivery of 5-Fluorouracil using high pressure homogenization-emulsification as the preparation method and in vitro.in vivo studies. Drug Dev Ind Pharm 2008;34:107–115
   PubMed Web of Science ®Google Scholar
• Hans ML, Lowman AM. Biodegradable nanoparticles for drug delivery and targeting. J Control Rel 2002;6:319–327
   Google Scholar
• Jafari S, Assadpoor E, He Y, Bhandari B. Re-coalescence of emulsion droplets during high-energy emulsification. Food Hydrocoll 2008;22:1191–1202
   Web of Science ®Google Scholar
• Pillai RR, Somayaji SN, Rabinovich M, et al. Nafcillin-loaded PLGA nanoparticles for treatment of osteomyelitis. Biomed Mater (Bristol, England) 2008;3:034114
   Web of Science ®Google Scholar
• Yeo Y, Park K. Control of encapsulation efficiency and initial burst in polymeric microparticle systems. Arch Pharmacal Res 2004;27:1–12
   PubMed Web of Science ®Google Scholar
• Peltonen L, Aitta J, Hyvönen S, et al. Improved entrapment efficiency of hydrophilic drug substance during nanoprecipitation of poly(l)lactide nanoparticles. AAPS PharmSciTech 2004;5:E16
   PubMed Web of Science ®Google Scholar
• Péan JM, Venier-Julienne MC, Boury F, et al. NGF release from poly(d,l-lactide-co-glycolide) microspheres. Effect of some formulation parameters on encapsulated NGF stability. J Control Rel 1998;56:175–187
   PubMed Web of Science ®Google Scholar
• Yu X, Zipp GL, Davidson GW. The effect of temperature and pH on the solubility of quinolone compounds: estimation of heat of fusion. Pharmaceut Res 1994;11:522–527
   PubMed Web of Science ®Google Scholar
• Rosca ID, Watari F, Uo M. Microparticle formation and its mechanism in single and double emulsion solvent evaporation. J Control Rel 2004;99:271–280
   PubMed Web of Science ®Google Scholar
• Esmaeili F, Hosseini-Nasr M, Rad-Malekshahi M, et al. Preparation and antibacterial activity evaluation of rifampicin-loaded poly lactide-co-glycolide nanoparticles. Nanomedicine 2007;3:161–167
   PubMed Web of Science ®Google Scholar
• Song X, Zhao Y, Hou S, et al. Dual agents loaded PLGA nanoparticles: systematic study of particle size and drug entrapment efficiency. Eur J Pharm Biopharm 2008;69:445–453
   PubMed Web of Science ®Google Scholar
• Musumeci T, Ventura CA, Giannone I, et al. PLA/PLGA nanoparticles for sustained release of docetaxel. Int J Pharm 2006;325:172–179
   PubMed Web of Science ®Google Scholar
• Mohammadi G, Valizadeh H, Barzegar-Jalali M, et al. Development of azithromycin-PLGA nanoparticles: physicochemical characterization and antibacterial effect against Salmonella typhi. Colloid Surf B-Biointerfaces 2010;80:34–39
   PubMed Web of Science ®Google Scholar
• Roser M, Fischer D, Kissel T. Surface-modified biodegradable albumin nano- and microspheres. II: effect of surface charges on in vitro phagocytosis and biodistribution in rats. Eur J Pharm Biopharm 1998;46:255–263
   PubMed Web of Science ®Google Scholar
• Kumar G, Sharma S, Shafiq N, et al. Optimization, in vitro–in vivo evaluation, and short-term tolerability of novel levofloxacin-loaded PLGA nanoparticle. J Pharm Sci 2012;101:2165–2176
   PubMed Web of Science ®Google Scholar
• Leroueil-Le Verger M, Fluckiger L, et al. Preparation and characterization of nanoparticles containing an antihypertensive agent. Eur J Pharm Biopharm 1998;46:137–143
   PubMed Web of Science ®Google Scholar
• Kim H, Fassihi R. Application of a binary polymer system in drug release rate modulation. 1. Characterization of release mechanism. J Pharm Sci 1997;86:316–322
   PubMed Web of Science ®Google Scholar
• Ritger P, Peppas N. A simple equation for description of solute release II. Fickian and anomalous release from swellable devices. J Control Rel 1987;5:37–42
   Google Scholar
• Yu L, Zhang H, Cheng S-X, et al. Study on the drug release property of cholesteryl end-functionalized poly(epsilon-caprolactone) microspheres. J Biomed Mater Res B Appl Biomater 2006;77:39–46
   PubMed Web of Science ®Google Scholar