References
- Okayasu I, Hatakeyama S, Yamada M. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 1990;98:694–702
- Jain A, Gupta Y, Jain SK. Perspectives of biodegradable natural polysaccharides for site-specific drug delivery to the colon. J Pharm Sci 2007;10:86–128
- Katz MDS, FACP. Update in medical therapy of ulcerative colitis: newer concepts and therapies. Gastroenterology 2005;39:557–569
- Liu Q, Li XH. Study on preparation and release of 5-aminosalicylic colon-specific delivery pellets controlled by pH and time of in vitro. J Tianjin Med Univ 2008;14:34–37
- Domènech E. Inflammatory bowel disease: current therapeutic options. Digestion 2006;73:67–76
- Hari PR, Chandy T, Sharma CP. Chitosan – calcium alginate beads for oral delivery of insulin. J Appl Polym Sci 1996;59:1795–1801
- Minami K, Hirayama F, Uekama K. Colon-specific drug delivery based on a cyclodextrin prodrug: release behavior of biphenylylacetic acid from its cyclodextrin conjugates in rat intestinal tracts after oral administration. J Pharm Sci 1998;87:715–720
- Prüsse U, Morawsky V, Dierich A. Encapsulation of microscopic catalysis in polyvinyl alcohol hydro gel beads. Federal Agricultural Research Centre 1998;118:137–146
- Kricheldorf HR. Syntheses and application of polylactides. Chemosphere 2001;43:49–54
- Hanauer B. Medical therapy for ulcerative colitis. Gastroenterology 2004;126:1582–1592
- Vaghani SS, Patel MM, Satish CS, et al. Synthesis and characterization of carboxymethyl chitosan hydrogel: application as pH-sensitive delivery for nateglinide. Curr Drug Deliv 2012;9:628–636
- Chen SC, Wua YC, Mi FL. A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery. J Control Release 2004;96:285–300
- Mumper RJ, Hoffman AS, Puolakkainen A, et al. Calcium-alginate beads for the oral delivery of transforming growth factor-β1 (TGF-β1): stabilization of TGF-β1 by the addition of polyacrylic acid within acid-treated beads. J Control Release 1994;30:241–251
- Downs EC, Robertson NE, Riss TL. Calcium alginate beads as a slow-release system for delivering angiogenic molecules in vivo and in vitro. J Cell Physiol 1992;152:422–429
- Zhang X, Sun X. Study on 5-aminosalicylic acid coated table colonic targeting drug delivery system. J Chin Hosp Pharm 2001;21:323–325
- Kajjari PB, Manjeshwar SL, Aminabhavi TM. Novel pH and temperature-responsive blend hydrogel microspheres of sodium alginate and PNIPAAm-g-GG for controlled release of isoniazid. AAPS PharmSciTech 2012;12:1147–1157
- Gupta VK, Beckert TE, Price JC. A novel pH- and time-based multi-unit potential colonic drug delivery system. I. Development. Int J Pharm 2001;213:83–91
- Epifano F, Genovese S, Carlucci G. Novel prodrugs for the treatment of colonic diseases based on 5-aminosalicylic acid, 4'-geranyloxyferulic acid, and auraptene: biological activities and analytical assays. Curr Drug Deliv 2012;10:112–121
- Surajit D, Chaudhury A, Yun NK. Preparation and evaluation of zinc–pectin–chitosan composite particles for drug delivery to the colon: role of chitosan in modifying in vitro and in vivo drug release. Int J Pharm 2011;406:11–20
- Kornbluth A, Sachar DB. Ulcerative colitis practice guidelines in adults: American college of gastroenterology, practice parameters committee. Am J Gastroenterol 2010;105:501–523
- Kang MH, Kang HC. pH-sensitive polymers for drug delivery. Macromol Res 2012;20:224–233
- Williams EC, Toomey R, Alcantar N. Controlled release niosome embedded chitosan system: effect of crosslink mesh dimensions on drug release. J Biomed Mater Res. Part A 2012;2012:100A:3296–3303
- Qiu Y, Kinam P. Environment-sensitive hydrogels for drug delivery. Adv Drug Deliv Rev 2012;64:49–60
- Lai ZN, Cui YD, Yan ZQ. Research on oxygen permeability of PVA-alginate-active carbon copolymer hydrogel. Mater Sci 2008;22:152–155
- Lai ZN, Cui YD, Liang CQ. Preparation of PVA-SA-PLA composite hydrogels and the diffusibility performance for NH4+. J Guangdong Univ Technol 2009;26:1–4
- Feng CY, Cui YY, Kang XM. Preparation and properties of blend microspheres of polyvinyl alcohol and sodium alginate. Chem Indus Eng 2010;27:381–386
- Hu ZJ. SPSS11. 5software in the orthogonal experimental design. Med Information 2007;20:737–740
- Ruhe D, Hua XB, Fan YS. Orthogonal experimental design, theoretical analysis method and its application. J Anhui Insti Archi Indust 2004;12:103–106
- Tursi A. Balsalazide plus high-potency probiotic preparation (VSL#3) in the treatment of acute mild-to-moderate ulcerative colitis and uncomplicated diverticulitis of the colon. J Clinical Gastroenterol 2008;42:119–122
- Wong TW, Nurjaya S. Drug release property of chitosan-pectinate beads and its changes under the influence of microwave. Eur J Pharmac Biopharma 2008;69:176–188
- Surajit D, Chaudhury A, Yun NK. Resveratrol-loaded calcium-pectinate beads: effects of formulation parameters on drug release and bead characteristics. J Pharm Sci 2010;99:840–860
- Zhang T, Li GY, Guo L. Synthesis of thermo-sensitive CS-g-PNIPAM/CMC complex nanoparticles for controlled release of 5-FU. Int J Bio Macromol 2012;51:1109–1115
- Zheng YL, Yang WL, Wang CC. Nanoparticles based on the complex of chitosan and polyaspartic acid sodium salt: preparation, characterization and the use for 5-fluorouracil delivery. Europ J Pharmac Biopharma 2007;67:621–631
- Allgayer H, Sonnenbichler J, Kruis W, Paumgartner G. Determination of the pK values of 5-aminosalicylic acid and N-acetylaminosalicylic acid and comparison of the lipid-water partition coefficients of sulfasalzine and its metabolites. Drug Res 1985;35:1457–1459