200
Views
3
CrossRef citations to date
0
Altmetric
Research Article

Impact of micromeritic properties of an active pharmaceutical ingredient on its compaction behavior

&
Pages 129-138 | Received 01 Aug 2012, Accepted 27 Sep 2013, Published online: 13 Nov 2013

References

  • Haleblian JK. Characterization of habits and crystalline modification of solids and their pharmaceutical applications. J Pharm Sci 1975;64:1269–1288
  • Mullin JW. Crystallization 2001. New York: Butterworth-Heinemann; 2001
  • Patel S, Kaushal AM, Bansal AK. Compression physics in the formulation development of tablets. Crit Rev Ther Drug Carrier Syst 2006;23:1–65
  • Rasenack N, Muller BW. Crystal habit and tableting behavior. Int J Pharm 2002;244:45–57
  • York P. Crystal engineering and particle design for the powder compaction process. Drug Dev Ind Pharm 1992;18:677–721
  • Patel S, Bansal AK. Prediction of mechanical properties of compacted binary mixtures containing high-dose poorly compressible drug. Int J Pharm 2011;403:109–114
  • Erdemir D, Lee AY, Myerson AS. Polymorph selection: the role of nucleation, crystal growth and molecular modeling. Curr Opin Drug Discov Dev 2007;10:746–755
  • Marshall PV, York P. Crystallization solvent induced solid-state and particulate modifications of nitrofurantoin. Int J Pharm 1989;55:257–263
  • Feng Y, Grant DJ, Sun CC. Influence of crystal structure on the tableting properties of n-alkyl 4-hydroxybenzoate esters (parabens). J Pharm Sci 2007;96:3324–3333
  • Di Martino P, Censi R, Barthelemy C, et al. Characterization and compaction behaviour of nimesulide crystal forms. Int J Pharm 2007;342:137–144
  • Feng Y, Grant DJ. Influence of crystal structure on the compaction properties of n-alkyl 4-hydroxybenzoate esters (parabens). Pharm Res 2006;23:1608–1616
  • Garekani HA, Sadeghi F, Badiee A, et al. Crystal habit modifications of ibuprofen and their physicomechanical characteristics. Drug Dev Ind Pharm 2001;27:803–809
  • Sun C, Grant DJ. Influence of crystal shape on the tableting performance of L-lysine monohydrochloride dihydrate. J Pharm Sci 2001;90:569–579
  • Teychené S, Sicre N, Biscans B. Is spherical crystallization without additives possible? Chem Eng Res Design 2010;88:1631–1638
  • Szabó-Révész P, Hasznos-Nezdei M, Farkas B, et al. Crystal growth of drug materials by spherical crystallization. J Crystal Growth 2002;237–239:2240–2245
  • Katta J, Rasmuson ÅC. Spherical crystallization of benzoic acid. Int J Pharm 2008;348:61–69
  • Kawashima Y, Imai M, Takeuchi H, et al. Improved flowability and compactibility of spherically agglomerated crystals of ascorbic acid for direct tableting designed by spherical crystallization process. Powder Technol 2003;130:283–289
  • Sorbera LA, del Fresno M, Leeson PA, et al. DPC-083. Drugs Future 2002;27:331–338
  • Amidon GL, Lennernas H, Shah VP, Crison JR. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res 1995;12:413–420
  • Badawy SI, Lee TJ, Menning MM. Effect of drug substance particle size on the characteristics of granulation manufactured in a high-shear mixer. AAPS PharmSciTech 2000;1:55--61
  • Wong LW, Pilpel N. The effect of particle shape on the mechanical properties of powders. Int J Pharm 1990;59:145–154
  • Karehill PG, Nyström C. Studies on direct compression of tablets. XXIII. The importance of surface roughness for the compactability of some directly compressible materials with different bonding and volume reduction properties. Int J Pharm 1990;64:35–43
  • Alderbörn G, Nyström C. Studies on direct compression of tablets. Part 3. Effect on tablet strength of changes in particle shape and texture obtained by milling. Acta Pharm Suec 1982;19:381–390
  • Alderbörn G, Borjesson E, Glazer M, Nyström C. Studies on direct compression of tablets. XIX. The effect of particle size and shape on the mechanical strength of sodium bicarbonate tablets. Acta Pharm Suec 1988;25:31–40

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.