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Research Article

Solid-state stability and compatibility studies of clavulanate potassium

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Pages 146-152 | Received 11 Apr 2013, Accepted 02 Oct 2013, Published online: 13 Nov 2013

References

  • Lister PD. Beta-lactamase inhibitor combinations with extended-spectrum penicillins: factors influencing antibacterial activity against enterobacteriaceae and Pseudomonas aeruginosa. Pharmacotherapy 2000;20:213–218
  • Salvo F, De Sarro A, Caputi AP, Polimeni G. Amoxicillin and amoxicillin plus clavulanate: a safety review. Expert Opin Drug Saf 2009;8:111–118
  • Coulthurst SJ, Barnard AM, Salmond GP. Regulation and biosynthesis of carbapenem antibiotics in bacteria. Nat Rev Microbiol 2005;3:295–306
  • Hugonnet JE, Tremblay LW, Boshoff HI, et al. Meropenem-clavulanate is effective against extensively drug-resistant Mycobacterium tuberculosis. Science 2009;323:1215–1218
  • England K, Boshoff HIM, Arora K. Meropenem-clavulanic acid shows activity against Mycobacterium tuberculosis in vivo. Antimicrob Agents Chemother 2012;56:3384–3387
  • Dauby N, Muylle I, Mouchet F, et al. Meropenem/clavulanate and linezolid treatment for extensively drug-resistant tuberculosis. Pediatr Infect Dis J 2011;30:812–813
  • Saudagar PS, Survase SA, Singhal RS. Clavulanic acid: a review. Biotechnol Adv 2008;26:335–351
  • Finlay J, Miller L, Poupard JA. A review of the antimicrobial activity of clavulanate. J Antimicrob Chemother 2003;52:18–23
  • Carvalho Santos V, Brandão Pereira JF, Brandão Haga R, et al. Stability of clavulanic acid under variable pH, ionic strength and temperature conditions. A new kinetic approach. Biochem Eng J 2009;45:89–93
  • Martin J, Méndez R, Alemany T. Studies on clavulanic acid. Part 1. Stability of clavulanic acid in aqueous solutions of amines containing hydroxy groups. J Chem Soc Perkin Trans 1989;2:223–226
  • Finn MJ, Harris MA, Hunt E, Zomaya II. Studies on the hydrolysis of clavulanic acid. J Chem Soc Perkin Trans 1984;1:1345–1349
  • Sanchez PA, Toney JH, Thomas JD, Berger JM. A sensitive coupled HPLC/electrospray mass spectrometry assay for SPM-1 metallo-beta-lactamase inhibitors. Assay Drug Dev Technol 2009;7:170–179
  • Haginaka J, Nakagawa T, Uno T. Stability of clavulanic acid in aqueous solution. Chem Pharm Bull 1981;29:3334–3341
  • Haginaka J, Yasuda H, Uno T, Nakagawa T. Degradation of clavulanic acid in aqueous alkaline solution – isolation and structural investigation of degradation products. Chem Pharm Bull 1985;33:218–224
  • Lynch HC, Yang Y. Degradation products of clavulanic acid promote clavulanic acid production in cultures of Streptomyces clavuligerus. Enzyme Microbial Technol 2004;34:48–54
  • Bersanettia PA, Almeidab RM, Barbozac M, et al. Kinetic studies on clavulanic acid degradation. Biochem Eng J 2005;23:31–36
  • Brethauer S, Held M, Panke S. Clavulanic acid decomposition is catalyzed by the compound itself and by its decomposition products. J Pharm Sci 2008;97:3451–3455
  • Martin J, Mendez R, Salto F. Studies on clavulanic acid 2. The catalytic effect of metal-ions on the hydrolysis of clavulanic acid. J Chem Soc Perkin Trans 1989;2:227–231
  • Chadha R, Kashid N, Jain DV. Microcalorimetric evaluation of the in vitro compatibility of amoxicillin/clavulanic acid and ampicillin/sulbactam with ciprofloxacin. J Pharm Biomed Anal 2004;36:295–307
  • Nugrahani I, Asyarie S, Soewandhi SN, Ibrahim S. The antibiotic potency of amoxicillin-clavulanate co-crystal. Int J Pharmacol 2007;3:475–481
  • Antovska P, Petrusevski G, Mareski P. Solid-state compatibility screening of excipients suitable for development of indapamide sustained release solid-dosage formulation. Pharm Dev Tech 2013;8:481–489
  • Parmar N, Amin S, Singla N, Kohli K. The solution, solid state stability and kinetic investigation in degradation studies of lercanidipine: study of excipients compatibility of lercanidipine. Pharm Dev Tech 2012;6:730–740
  • The European Pharmacopoeia VIII. Strasbourg, France; 2010
  • Frisch M, Trucks G, Schlegel H, et al. Gaussian 03, Revision B.05. Pittsburgh (PA): Gaussian, Inc.; 2003
  • Cielecka-Piontek J, Paczkowska M, Zalewski P, et al. Theoretical and experimental analytical studies on potassium clavulanate. Curr Issues Pharmacy Med Sci 2012;25:317–321
  • Sajonz P, Natishan TK, Wu Y, et al. Development and validation of a sensitive and robust wipe-test method for the detection and quantification of the antibiotic ertapenem and its primary degradates in a pharmaceutical manufacturing environment. J Liquid Chromatogr Relat Technol 2005;28:713–725
  • Ito N, Suzuki M, Kusai A, Takayama K. Effect of initial concentration on stability of panipenem in aqueous solution. Chem Pharm Bull 2005;53:323–327
  • Cielecka-Piontek J, Jelińska A. Catalytic effect of buffers on the degradation of doripenem in aqueous solutions. React Kinet Mech Cat 2011;102:37–39
  • Hassan N, Abdel-Moety E, Elragehy N, Rezk M. Selective determination of ertapenem in the presence of its degradation product. Spectrochim Acta A 2009;72:915–917
  • Cielecka-Piontek J, Lunzer A, Jelińska A. Stability-indicating derivative spectrophotometry method for the determination of biapenem in the presence of its degradation products. Cent Eur J Chem 2011;9:35–38
  • Cielecka-Piontek J, Jelińska A. The UV-derivative spectrophotometry for the determination of doripenem in the presence of its degradation products. Spectrochim Acta A 2010;77:554–557
  • Waterman KC, Gerst P, Dai Z. A generalized relation for solid-state drug stability as a function of excipient dilution: temperature-independent behavior. J Pharm Sci 2012;101:4170–4177

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