A critical review on tablet disintegration

References

• Noyes AA, Whitney WR. The rate of solution of solid substances in their own solution. J Am Chem Soc 1897;19:930–934
   Google Scholar
• Nernst W. Theorie der Reaktionsgeschwindigkeit in heterogenen Systemen. Z Phys Chem 1903;47:52–55
   Google Scholar
• Brunner E. Reaktionsgeschwindigkeit in heterogenen Systemen. Z Phys Chem 1903;47:56–102
   Google Scholar
• Guyot-Hermann AM. Tablet disintegration and disintegrating agents. STP Pharma Sci 1992;2:445–462
   Google Scholar
• List PH, Muazzam UA. Quellung – die treibende Kraft beim Tablettenzerfall, 1. Mitteilung. Pharm Ind 1979;41:459–464
   Google Scholar
• Patel NR, Hopponen RE. Mechanism of action of starch as a disintegrating agent in aspirin tablets. J Pharm Sci 1966;55:1065–1068
   Web of Science ®Google Scholar
• Nogami H, Nagai T, Fukuoka E, Sonobe T. Disintegration of the aspirin tablets containing potato starch and microcrystalline cellulose in various concentrations. Chem Pharm Bull 1969;17:1450–1455
   PubMed Web of Science ®Google Scholar
• Khan KA, Rhodes CT. Water-sorption properties of tablets disintegrants. J Pharm Sci 1975;64:447–451
   PubMed Web of Science ®Google Scholar
• Shangraw R, Mitrevej A, Shah M. A new era of tablet disintegrants. Pharm Technol 1980;4:49–57
   Google Scholar
• Rudnic EM, Rhodes CT, Welch S, Bernardo P. Evaluations of the mechanism of disintegrant action. Drug Dev Ind Pharm 1982;8:87–109
   Web of Science ®Google Scholar
• Washburn EW. The dynamics of capillary flow. Phys Rev 1921;17:273–283
   Google Scholar
• Bronnsack AH. Polyplasdone XL – properties and practical data concerning its use as tablet binding and disintegration substance. Pharm Ind 1978;40:1255–1263
   Google Scholar
• Buehler V. Kollidon. Polyvinylpyrrolidone excipients for the pharmaceutical industry. 9th ed. Ludwigshafen: BASF SE Pharma Ingredients & Services; 2008
   Google Scholar
• Shotton E, Leonard GS. Effect of intragranular and extragranular disintegrating agents on particle size of disintegrated tablets. J Pharm Sci 1976;65:1170–1174
   PubMed Web of Science ®Google Scholar
• Van Kamp HV, Bolhuis GK, Lerk CF. Improvement by super disintegrants of the properties of tablets containing lactose, prepared by wet granulation. Pharm Weekblad 1983;5:165–171
   PubMedGoogle Scholar
• Colombo P, Conte U, Caramella C, et al. Disintegrating force as a new formulation parameter. J Pharm Sci 1984;73:701–705
   PubMed Web of Science ®Google Scholar
• Smallenbroek AJ, Bolhuis GK, Lerk CF. The effect of particle size of disintegrants on the disintegration of tablets. Pharm Weekblad 1981;3:1048–1051
   Web of Science ®Google Scholar
• List PH, Muazzam UA. Quellung – die treibende Kraft beim Tablettenzerfall, 2. Mitteilung. Pharm Ind 1979;41:1075–1077
   Google Scholar
• Desai PM, Er PXH, Liew CV, Heng PWS. Functionality of disintegrants and their mixtures in enabling fast disintegration of tablets by a quality by design approach. AAPS PharmSciTech 2014;15:1093–1104
   PubMed Web of Science ®Google Scholar
• Basu B, Bagadiya A, Makwana S, et al. Formulation and evaluation of fast dissolving tablets of cinnarizine using superdisintegrant blends and subliming material. J Adv Pharm Technol Res 2011;2:266–273
   PubMedGoogle Scholar
• Quodbach J, Kleinebudde P. A new apparatus for real-time assessment of the particle size distribution of disintegrating tablets. J Pharm Sci 2014;103:3657–3665
   PubMed Web of Science ®Google Scholar
• 8.1 EP. 2.9.1 Disintegration of tablets and capsules. In: Commission EP, editor. Strasbourg, France: European Directorate for the Quality of Medicines (EDQM);2014:285–287
   Google Scholar
• Caramella C, Colombo P, Conte U, et al. Water uptake and disintegrating force measurements: towards a general understanding of disintegration mechanisms. Drug Dev Ind Pharm 1986;12:1749–1766
   Web of Science ®Google Scholar
• Van Kamp HV, Bolhuis GK, De Boer AH, et al. The role of water uptake on tablet disintegration: design of an improved method for penetration measurements. Pharm Acta Helv 1986;61:22–29
   PubMedGoogle Scholar
• Caramella C. Novel methods for disintegrant characterization, Part I. Pharm Technol Int 1990;2:30–42
   Google Scholar
• Caramella C. Novel methods for disintegrant characterization, Part II. Pharm Technol Int 1990;2:30–37
   Google Scholar
• Chowhan ZT. The effect of low and high humidity ageing on the hardness, disintegration time and dissolution rate of dibasic calcium phosphate based tablets. J Pharm Pharmacol 1980;32:10–14
   PubMed Web of Science ®Google Scholar
• Mesnier X, Althaus TO, Forny L, et al. A novel method to quantify tablet disintegration. Powder Technol 2013;238:27–34
   Web of Science ®Google Scholar
• Quodbach J, Moussavi A, Tammer R, et al. Tablet disintegration studied by high-resolution real-time magnetic resonance imaging. J Pharm Sci 2014;103:249–255
   PubMed Web of Science ®Google Scholar
• Desai PM, Liew CV, Heng PWS. Understanding disintegrant action by visualization. J Pharm Sci 2012;101:2155–2164
   PubMed Web of Science ®Google Scholar
• Faroongsarng D, Peck GE. The swelling & water uptake of tablets iii: moisture sorption behavior of tablet disintegrants. Drug Dev Ind Pharm 1994;20:779–798
   Web of Science ®Google Scholar
• Hüttenrauch R, Jacob J. Wirkungsmechanismus von Sprengmitteln in Komprimaten. Pharmazie 1970;26:293–298
   Google Scholar
• Guyot-Hermann AM, Ringard J. Disintegration mechanisms of tablets containing starches. Hypothesis about the particle-particle repulsive force. Drug Dev Ind Pharm 1981;7:155–177
   Web of Science ®Google Scholar
• Thibert R, Hancock B. Direct visualization of superdisintegrant hydration using environmental scanning electron microscopy. J Pharm Sci 1996;85:1255–1258
   PubMed Web of Science ®Google Scholar
• Lendlein A, Kelch S. Shape-memory polymers – from temporary shape to permanent shape. Angew Chem Int Ed 2002;41:2035–2057
   PubMed Web of Science ®Google Scholar
• Lowenthal W. Mechanism of action of starch as a tablet disintegrant. V. Effect of starch grain deformation. J Pharm Sci 1972;61:455–459
   PubMed Web of Science ®Google Scholar
• Erdös S, Bezegh A. Studies on the mechanism of disintegration. Pharm Ind 1977;39:1130–1135
   Google Scholar
• Quodbach J, Kleinebudde P. Performance of tablet disintegrants: impact of storage conditions and relative tablet density. Pharm Dev Technol. 2014. [Epub ahead of print]. doi: 10.3109/10837450.2014.920357
   PubMed Web of Science ®Google Scholar
• Quodbach J, Kleinebudde P. Systematic classification of tablet disintegrants by water uptake and force development kinetics. J Pharm Pharmacol 2014;66:1429–1438
   PubMed Web of Science ®Google Scholar
• Curlin LC. A note on tablet disintegration with starch. J Am Pharm Assoc 1955;44:16. doi: 10.1002/jps.3030440107
   Google Scholar
• Shotton E, Leonard GS. Effect of intra- and extragranular maize starch on disintegration of compressed tablets. J Pharm Pharmacol 1972;24:798–803
   PubMed Web of Science ®Google Scholar
• Leuenberger H, Rohera BD, Haas C. Percolation theory – a novel approach to solid dosage form design. Int J Pharm 1987;38:109–115
   Web of Science ®Google Scholar
• Luginbühl R, Leuenberger H. Use of percolation theory to interpret water uptake, disintegration time and intrinsic dissolution rate of tablets consisting of binary mixtures. Pharm Acta Helv 1994;69:127–134
   Google Scholar
• Matsumaru H. Studies on the mechanism of tablet compression and disintegration. IV. Evolution of wetting heat and its reduction by compressional force. Yakugaku Zasshi 1959;79:63–64
   Google Scholar
• Kanig JL, Rudnic EM. The mechanisms of disintegrant action. Pharm Technol 1984;8:50–63
   Google Scholar
• Ganderton D, Fraser DR. Some observations of the penetration and disruption of tablets by water. J Pharm Pharmacol 1970;22:95–103
   Web of Science ®Google Scholar
• Gordon MS, Rudraraju VS, Rhie JK, Chowhan ZT. The effect of aging on the dissolution of wet granulated tablets containing super disintegrants. Int J Pharm 1993;97:119–131
   Web of Science ®Google Scholar
• Gordon MS, Rudraraju VS, Dani K, Chowhan ZT. Effect of the mode of super disintegrant incorporation on dissolution in wet granulated tablets. J Pharm Sci 1993;82:220–226
   PubMed Web of Science ®Google Scholar
• Ferrari F, Bertoni M, Bonferoni M, et al. Influence of porosity and formula solubility on disintegrant efficiency in tablets. STP Pharma Practiques 1995;5:116–121
   Web of Science ®Google Scholar
• Late SG, Yu Y, Banga A. Effects of disintegration-promoting agent, lubricants and moisture treatment on optimized fast disintegrating tablets. Int J Pharm 2009;365:4–11
   PubMed Web of Science ®Google Scholar
• Quodbach J, Kleinebudde P. Impact of the porous network on the disintegration behavior of tablets containing superdisintegrants. Poster session presented at 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technologie, Istanbul, Turkey; 2012
   Google Scholar
• Kristensen HG, Schaefer T. Granulation. A review on pharmaceutical wet-granulation. Drug Dev Ind Pharm 1987;13:803–872
   Web of Science ®Google Scholar
• Kleinebudde P. Roll compaction/dry granulation: pharmaceutical applications. Eur J Pharm Biopharm 2004;58:317–326
   PubMed Web of Science ®Google Scholar
• Jivraj M, Martini LG, Thomson C. An overview of the different excipients useful for the direct compression of tablets. Pharm Sci Technol Today 2000;3:58–63
   PubMedGoogle Scholar
• Zhao N, Augsburger L. The influence of granulation on super disintegrant performance. Pharm Dev Technol 2006;11:47–53
   PubMed Web of Science ®Google Scholar
• Faure A, York P, Rowe RC. Process control and scale-up of pharmaceutical wet granulation processes: a review. Eur J Pharm Biopharm 2001;52:269–277
   PubMed Web of Science ®Google Scholar
• Gould P, Tan SB. The effect of recompression on disintegrant efficiency in tablets prepared by wet granulation. Drug Dev Ind Pharm 1985;11:441–460
   Web of Science ®Google Scholar
• Lerk CF, Bolhuis GK, de Boer AH. Effect of microcrystalline cellulose on liquid penetration in and disintegration of directly compressed tablets. J Pharm Sci 1979;68:205–211
   PubMed Web of Science ®Google Scholar
• Schaefer T, Holm P, Kristensen HG. Melt granulation in a laboratory scale high shear mixer. Drug Dev Ind Pharm 1990;16:1249–1277
   Web of Science ®Google Scholar
• Passerini N, Caloger G, Albertini B, Rodriguez L. Melt granulation of pharmaceutical powders: a comparison of high-shear mixer and fluidised bed processes. Int J Pharm 2010;391:177–186
   PubMed Web of Science ®Google Scholar
• Van Melkebeke B, Vermeulen B, Vervaet C, Remon JP. Melt granulation using a twin-screw extruder: a case study. Int J Pharm 2006;326:89–93
   PubMed Web of Science ®Google Scholar
• Perissutti B, Rubessa F, Moneghini M, Voinovich D. Formulation design of carbamazepine fast-release tablets prepared by melt granulation technique. Int J Pharm 2003;256:53–63
   PubMed Web of Science ®Google Scholar
• Gordon MS, Chowhan ZT. The effect of aging on disintegrant efficiency in direct compression tablets with varied solubility and hygroscopicity, in terms of dissolution. Drug Dev Ind Pharm 1990;16:437–447
   Web of Science ®Google Scholar
• Marais AF, Song M, de Villiers MM. Effect of compression force, humidity and disintegrant concentration on the disintegration and dissolution of directly compressed furosemide tablets using croscarmellose sodium as disintegrant. Trop J Pharm Res 2003;2:125–135
   Google Scholar