Advanced search
Publication Cover
Pharmaceutical Development and Technology Volume 21, 2016 - Issue 6
Submit an article Journal homepage
362
Views
2
CrossRef citations to date
0
Altmetric
Research Article

Improving tablet coating robustness by selecting critical process parameters from retrospective data

A. GalíDepartment of Pharmacy and Pharmaceutical Technology, University of Barcelona, Barcelona, Spain and ;Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Barcelona, Barcelona, SpainCorrespondence[email protected]
,
E. García-MontoyaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
,
M. AscasoDepartment of Pharmacy and Pharmaceutical Technology, University of Barcelona, Barcelona, Spain and
,
P. Pérez-LozanoDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
,
J. R. TicóDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
,
M. MiñarroDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
&
J. M. Suñé-NegreDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
 show all
Pages 688-697 | Received 11 Feb 2015, Accepted 23 Apr 2015, Published online: 27 May 2015

References

  • Puñal-Peces D, García-Montoya E, Manich A, et al. Approach to design space from retrospective quality data. Pharm Dev Technol 2014;1:1–13
  • Toschkoff G, Khinast JG. Mathematical modeling of the coating process. Int J Pharm 2013;457:407–422
  • Pandey P, Turton R, Joshi N, et al. Scale-up of a pan-coating process. Pharm Sci Tech 2006;7:Art 102
  • Pandey P, Bindra DS. Real time monitoring of thermodynamic microenvironment in a pan coater. J Pharm Sci 2013;102:336–340
  • Tobiska S, Kleinebudde P. Coating uniformity and coating efficiency in a Bohle lab-coater using oval tablets. Eur J Pharm Biopharm 2003;56:3–9
  • Ketterhagen WR. Modeling the motion and orientation of various pharmaceutical tablet shapes in a film coating pan using DEM. Int J Pharm 2011;409:137–149
  • Porter SC, Verseput RP, Cunningham R. Process optimization using design of experiments. Pharm Tech 1997;21:60–70
  • Rege BD, Gawel J, Kou JH. Identification of critical process variables for coating actives onto tablets via statistically designed experiments. Int J Pharm Sci 2002;237:87–94
  • Tobiska S, Kleinebudde P. Coating uniformity: influence of atomizing air pressure. Pharm Dev Technol 2003;8:39–46
  • Tobiska S, Kleinebudde P. A simple method for evaluating the mixing efficiency of a new type of pan coater. Int J Pharm 2001;224:141–149
  • Patel JK, Shah AM, Sheth NR. Aqueous-based film coating of tablets: study the effect of critical process parameters. Int J Pharm Tech Res 2009;1:235–240
  • Just S, Toschkoff G, Funke A, et al. Optimization of the inter-tablet coating uniformity for an active coating process at lab and pilot scale. Int J Pharm 2013;457:1–8
  • Wilson KE, Crossman E. The influence of tablet shape and pan speed on intra-tablet film coating uniformity. Drug Dev Ind Pharm 1997;23:1239–1243
  • Freireich B, Wassgren C. Intra-particle coating variability: analysis and Monte-Carlo simulations. Chem Eng Sci 2010;65:1117–1124
  • Kalbag A, Wassgren C. Inter-tablet coating variability: tablet residence time variability. Chem Eng Sci 2009;64:2705–2717
  • Kalbag A, Wassgren C, Penumetcha SS, Pérez-Ramos JD. Inter-tablet coating variability: residence times in a horizontal pan coater. Chem Eng Sci 2008;63:2881–2894
  • Brock D, Zeitler JA, Funke A, et al. Evaluation of critical process parameters for inter-tablet coating uniformity of active-coated GITS using Terahertz pulsed imaging. Eur J Pharm Biopharm 2014;88:434–442
  • Brock D, Zeitler JA, Funke A, et al. Evaluation of critical process parameters for intra-tablet coating uniformity using terahertz pulsed imaging. Eur J Pharm Biopharm 2013;85:1122–1129

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.