30
Views
13
CrossRef citations to date
0
Altmetric
Research Article

Solid Tumor Chemotherapy and in Vivo Distribution of Fluorouracil Following Administration in Poly(L-Lactic Acid) Microspheres

, , , , , & show all
Pages 151-160 | Received 29 Aug 1996, Accepted 06 Dec 1996, Published online: 27 Sep 2008

References

  • Mehta R. C., Jeyanthi R., Calis S., Thanoo B. C., Burton K. W., DeLuca P. K. Biodegradable microspheres as depot system for parenteral delivery of peptide drugs. J. Control. Release 1994; 29: 375–384
  • Grubb G., Welch J., Cole L., Goldsmith A., Riveria R. A. Comparative evaluation of the safety and contraceptive effectiveness of 65 mg and 100 mg of 90-day norethindrone microspheres for controlled release steroid contraception: Phase II study. Fertil. Steril 1989; 51: 803–811
  • Yolles S., Eldridge J., Leafe T. D., Woodland J. H., Blake D. R., Meyer F. J. Long-acting delivery systems for narcotic antagonists. Adv. Exp. Med. Biol 1973; 47: 177–183
  • Wise D., McCormick G. F., Willet G. P., Anderson L. C. Sustained release of an antimalarial drug using a copolymer at glycolic/lactic acid. Life Sci 1976; 19: 867–872
  • Hecquet B., Chabot F., Delatone G., Fournier C., Hilati S., Cambies S. L., Depadt G., Vert M. In vivo sustained release of cisplatin from bioresorbable implants in mice. Anticancer Res 1986; 6: 1251–1261
  • Strobel J., Laughin T. J., Astray F., Lilly M. D., Perkins B. H., Dunn R. L. Controlled release systems for anticancer agents. Proc. Int. Symp. Control. Rel. Bioact. Mater 1980; 7: 129
  • Sanders L. M., Kent J. S., McRae G. I., Vickery B. H., Tice T. R., Lewis D. H. Controlled release of an LHRH analogue from poly (dl-lactide-co-glycolide) microspheres. J. Pharm. Sci 1984; 73: 1294–1301
  • Parker W. B., Cheng Y. C. Metabolism and mechanism of action of 5-fluorouracil. Pharm. Ther 1990; 48: 381–395
  • Bruijin E. A., Oosteram A. T., Tjaden U. R. Site specific delivery of 5-fluorouracil with 5-deoxy-5-fluorouridine. Reg. Cancer Treat 1989; 2: 61–76
  • Ciftci K., Kas H. S., Hincal A. A. In vitro and in vivo evaluation of PLAGA microspheres containing 5-FU prepared by a solvent evaporation method. Int. J. Pharm 1996; 131: 73–82
  • Ciftci K. Preparation and in vitro-in vivo evaluation of bio-degradable microspheres containing 5-fluorouracil. Ph.D. thesis, University of Hacettepe, Turkey 1993
  • Ciftci K., Hincal A. A., Kas H. S., Ercan M., Ruacan S. Micro-spheres of 5-FU using poly(dl-lactic acid), In vitro release properties and distribution in mice after i.v. administration. Eur. J. Pharm 1994; 1: 249–258
  • Aamdal S., Oystein F., Pihl A. Human tumor xenografts transplanted under the renal capsule of conventional mice. Growth rates and host immune response. Int. J. Cancer 1984; 34: 725–730
  • Bogden A., Cobb W., Lepage D. J., Haskel P. Chemotherapy responsiveness of human rumors as first transplant generation xenografts in the normal mouse. Cancer 1981; 48: 10–20
  • Fingert H. J., Chen Z., Mizrahi N., Gajewski W. H., Bamberg M. P., Kradin R. L. Rapid growth of human cancer cells in a mouse model with fibrin clot subrenal capsule assay. Cancer Res 1987; 47: 3824–3829
  • Krause J., Schwarz A., Rodhewald P. Polylactide acid nano-spheres, a colloidal drug delivery system for lipophilic drugs. Int. J. Pharm 1985; 27: 145–155
  • Basic Pathology, S. L. Robins, V. Kumar. W B. Saunders. 1987; 1–20
  • Jalil R., Nixon J. R. Microencapsulation using poly(L-lactic acid). IV: Release properties of microcapsules containing pheno-barbitone. J. Microencapsulation 1990; 7: 53–66
  • Bamba M., Puisieux F., Marty J. P., Carstensen J. T. Release mechanism in gel forming sustained release preparations. Int. J. Pharm 1979; 2: 307–315
  • Bos R. R. M., Rozema F. R., Boering G., Leenslag J. W., Pennigs A. J., Verwey A. B. In vivo and in vitro degradation of poly(L-lactide) used for fracture fixation. Adv. Biomater 1988; 8: 245–250
  • Izumikawa S., Yoshioka S., Aso Y., Takeda Y. Preparation of poly(L-lactide) microspheres different crystalline morphology and effect of crystalline morphology on drug release rate. J. Control. Rel 1991; 15: 133–140
  • Higuchi T. Mechanism of sustained action medication. Theoretical analysis of rate release of solid drugs dispersed in solid matrix. J. Pharm. Sci 1963; 52: 1145–1149
  • Vidmar V., Smolcic-Bubalo A., Jalsenjack I. Poly(lactic acid) microencapsulated oxytetracycline: In vitro and in vivo evaluation. J. Microencapsulation 1984; 1: 131–136
  • Tice T. R., Cowsar D. R. Biodegradable controlled release parentral systems. Pharm. Technol 1984; 8: 26–29
  • Sheffel U., Rhodes B. A., Wagner H. N. Albumin microspheres for study of the reticuloendothelial system. J. Nucl. Med 1972; 13: 498–503
  • Hazrati A. M., Akrawi S., Hickey A. J., Wedlund J., Macdonald J., DeLuca P. P. Tissue distribution of indium-III labeled poly-(glycolic acid) matrices following jugular and hepatic portal vein administration. J. Control. Rel 1989; 9: 205–214
  • Lay A. M., Vert M., Gautier J. C., Benoit J. P. Fate of 14-C poly-(lactide-co-glycolide) nanoparticles after intravenous and oral administration to mice. Int. J. Pharm 1994; 106: 201–211
  • Stolnik S., Dunn S. E., Garnett M. C., Davies M. C., et al. Surface modification of poly(lactide-co-glycolide) poly(lactide)-poly(ethylene-glycol) copolymers. Pharm. Res 1994; 11: 1800–1807

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.