Prehospital Administration of Tenecteplase for ST-segment Elevation Myocardial Infarction in a Rural EMS System

References

• Boersma E, Mercado N, Poldermans D, Gardien M, Vos J, Simoons ML. Acute myocardial infarction. Lancet. 2003;361:847–58.
   PubMed Web of Science ®Google Scholar
• Antman EM, Anbe DT, Armstrong PW, ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction; A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of Patients with Acute Myocardial Infarction). J Am Coll Cardiol. 2004;44:E1–E211.
   PubMedGoogle Scholar
• Nallamothu BK, Bates ER, Wang Y, Bradley EH, Krumholz HM. Driving times and distances to hospitals with percutaneous coronary intervention in the United States: implications for prehospital triage of patients with ST-elevation myocardial infarction. Circulation. 2006;113:1189–95.
   PubMed Web of Science ®Google Scholar
• Nallamothu BK, Bates ER. Percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: is timing (almost) everything? Am J Cardiol. 2003;92:824–6.
   PubMed Web of Science ®Google Scholar
• Moser DK, Kimble LP, Alberts MJ, Reducing delay in seeking treatment by patients with acute coronary syndrome and stroke: a scientific statement from the American Heart Association Council on Cardiovascular Nursing and Stroke Council. Circulation. 2006;114:168–82.
   PubMed Web of Science ®Google Scholar
• North Carolina State Center for Health Statistics. Leading causes of death in North Carolina. Available at: http://www.schs.state.nc.us/SCHS/data/lcd/lcd.cfm . Accessed July 8, 2010.
   Google Scholar
• Gilbert EH, Lowenstein SR, Koziol-McLain J, Barta DC, Steiner J. Chart reviews in emergency medicine research: where are the methods? Ann Emerg Med. 1996;27:305–8.
   PubMed Web of Science ®Google Scholar
• Nallamothu BK, Wang Y, Bradley EH, Comparing hospital performance in door-to-balloon time between the Hospital Quality Alliance and the National Cardiovascular Data Registry. J Am Coll Cardiol. 2007;50:1517–9.
   PubMedGoogle Scholar
• Taher T, Fu Y, Wagner GS, Aborted myocardial infarction in patients with ST-segment elevation: insights from the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen-3 Trial Electrocardiographic Substudy. J Am Coll Cardiol. 2004;44:38–43.
   PubMedGoogle Scholar
• Morrow DA, Antman EM, Sayah A, Evaluation of the time saved by prehospital initiation of reteplase for ST-elevation myocardial infarction: results of the Early Retavase–Thrombolysis in Myocardial Infarction (ER-TIMI) 19 trial. J Am Coll Cardiol. 2002;40:71–7.
   PubMedGoogle Scholar
• Schroder R, Wegscheider K, Schroder K, Dissmann R, Meyer-Sabellek W. Extent of early ST segment elevation resolution: a strong predictor of outcome in patients with acute myocardial infarction and a sensitive measure to compare thrombolytic regimens. A substudy of the International Joint Efficacy Comparison of Thrombolytics (INJECT) trial. J Am Coll Cardiol. 1995;26:1657–64.
   PubMedGoogle Scholar
• Diercks DB, Hollander JE. Catheterization laboratory activation: more about the drawing than the balloons. Ann Emerg Med. 2010;55:431–3.
   PubMedGoogle Scholar
• Morrison LJ, Verbeek PR, McDonald AC, Sawadsky BV, Cook DJ. Mortality and prehospital thrombolysis for acute myocardial infarction: a meta-analysis. JAMA. 2000;283: 2686–92.
   PubMed Web of Science ®Google Scholar
• Sayah AJ, Roe MT. The role of fibrinolytics in the prehospital treatment of ST-elevation myocardial infarction (STEMI). J Emerg Med. 2008;34:405–16.
   PubMedGoogle Scholar
• Castaigne AD, Hervé C, Duval-Moulin AM, Prehospital use of APSAC: results of a placebo-controlled study. Am J Cardiol. 1989;64:30A–33A.
   Google Scholar
• . Roth A, Barbash GI, Hod H, Should thrombolytic therapy be administered in the mobile intensive care unit in patients with evolving myocardial infarction? A pilot study. J Am Coll Cardiol. 1990;15:932–6.
   PubMedGoogle Scholar
• Weaver WD, Cerqueira M, Hallstrom AP, Prehospital-initiated vs hospital-initiated thrombolytic therapy. The Myocardial Infarction Triage and Intervention Trial. JAMA. 1993;270:1211–6.
   PubMedGoogle Scholar
• Cannon CP, Gibson CM, McCabe CH, TNK-tissue plasminogen activator compared with front-loaded alteplase in acute myocardial infarction: results of the TIMI 10B trial. Thrombolysis in Myocardial Infarction (TIMI) 10B Investigators. Circulation. 1998;98:2805–14.
   PubMedGoogle Scholar
• Murphy SA, Gibson CM, Van de Werf F, McCabe CH, Cannon CP. Comparison of errors in estimating weight and in dosing of single-bolus tenecteplase with tissue plasminogen activator (TIMI 10B and ASSENT I). Am J Cardiol. 2002;90:51–4.
   PubMedGoogle Scholar
• Jackson L, Kendall J, Castle N. Does prehospital thrombolysis increase the proportion of patients who have an aborted myocardial infarction? Emerg Med J. 2009;26:206–9.
   PubMedGoogle Scholar
• Lamfers EJ, Hooghoudt TE, Uppelschoten A, Stolwijk PW, Verheugt FW. Effect of prehospital thrombolysis on aborting acute myocardial infarction. Am J Cardiol. 1999;84:928–30.
   Google Scholar
• Lamfers EJ, Hooghoudt TE, Hertzberger DP, Schut A, Stolwijk PW, Verheugt FW. Abortion of acute ST segment elevation myocardial infarction after reperfusion: incidence, patients’ characteristics, and prognosis. Heart. 2003;89:496–501.
   PubMedGoogle Scholar
• Lamfers EJ, Schut A, Hertzberger DP, Prehospital versus hospital fibrinolytic therapy using automated versus cardiologist electrocardiographic diagnosis of myocardial infarction: abortion of myocardial infarction and unjustified fibrinolytic therapy. Am Heart J. 2004;147:509–15.
   PubMedGoogle Scholar
• Eckstein M, Cooper E, Nguyen T, Pratt FD. Impact of paramedic transport with prehospital 12-lead electrocardiography on door-to-balloon times for patients with ST-segment elevation myocardial infarction. Prehosp Emerg Care. 2009;13: 203–6.
   PubMed Web of Science ®Google Scholar
• Eckstein M, Koenig W, Kaji A, Tadeo R. Implementation of specialty centers for patients with ST-segment elevation myocardial infarction. Prehosp Emerg Care. 2009;13:215–22.
   PubMed Web of Science ®Google Scholar
• Lee CH, Van Gelder CM, Cone DC. Early cardiac catheterization laboratory activation by paramedics for patients with ST-segment elevation myocardial infarction on prehospital 12-lead electrocardiograms. Prehosp Emerg Care. 2010;14:153–8.
   PubMed Web of Science ®Google Scholar
• Welsh RC, Travers A, Senaratne M, Williams R, Armstrong PW. Feasibility and applicability of paramedic-based prehospital fibrinolysis in a large North American center. Am Heart J. 2006;152:1007–14.
   PubMedGoogle Scholar
• Bjorklund E, Stenestrand U, Lindback J, Svensson L, Wallentin L, Lindahl B. Pre-hospital thrombolysis delivered by paramedics is associated with reduced time delay and mortality in ambulance-transported real-life patients with ST-elevation myocardial infarction. Eur Heart J. 2006;27: 1146–52.
   PubMedGoogle Scholar
• Wallentin L, Goldstein P, Armstrong PW, Efficacy and safety of tenecteplase in combination with the low-molecular-weight heparin, enoxaparin, or unfractionated heparin in the prehospital setting: the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT)-3 PLUS randomized trial in acute myocardial infarction. Circulation. 2003;108: 135–42.
   PubMedGoogle Scholar
• Luepker RV, Raczynski JM, Osganian S, Effect of a community intervention on patient delay and emergency medical service use in acute coronary heart disease: the Rapid Early Action for Coronary Treatment (REACT) Trial. JAMA. 2000;284: 60–7.
   PubMedGoogle Scholar
• Aufderheide TP, Keelan MH, Hendley GE, Milwaukee Prehospital Chest Pain Project—phase I: feasibility and accuracy of prehospital thrombolytic candidate selection. Am J Cardiol. 1992;69:991–6.
   PubMedGoogle Scholar