Immunohistochemical investigation of the brain of aged dogs. I. Detection of neurofibrillary tangles and of 4-hydroxynonenal protein, an oxidative damage product, in senile plaques

References

• Ishii T, Hosoda Y, Ikegami N, Shimada H. Senile amyloid deposition. J Pathol 1983; 139: 1–22
   PubMed Web of Science ®Google Scholar
• Wright J R, Calkins E, Breen W J, Stolte G, Schultz R T. Relationship of amyloid to aging. Medicine 1969; 48: 39–60
   PubMed Web of Science ®Google Scholar
• Selkoe D J. The molecular pathology of Alzheimer's disease. Neuron 1991; 6: 487–498
   PubMed Web of Science ®Google Scholar
• Wisniewski T, Lalowski M, Bobik M, Russel M, Strosznajder J, Frangione B. Amyloid p 1–42. deposits do not lead to Alzheimer's neuritic plaques in aged dogs. Biochem J 1996; 313: 575–580
   PubMed Web of Science ®Google Scholar
• Uschida K, Nakayama H, Goto N. Pathological studies on cerebral amyloid angiopathy, senile plaques and amyloid deposition in visceral organs in aged dogs. J Vet Med Sci 1991; 53: 1037–1042
   PubMed Web of Science ®Google Scholar
• Bergeron G G, Ranalli P J, Miceli P N. Amyloid angiopathy in Alzheimer's disease. Can J Neurol Sci 1987; 14: 564–569
   PubMedGoogle Scholar
• Glenner G G, Henry J H, Fujihara S. Congophilic angiopathy in the pathogenesis of Alzheimer's degeneration. Ann Pathol 1981; 1: 120–129
   PubMed Web of Science ®Google Scholar
• Miller D L, Papayannopoulos I A, Styles J, Bobin S A, Lin Y Y, Biemann L K, Iqbal K. Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease. Arch Biochem Biophys 1993; 301: 41–52
   PubMed Web of Science ®Google Scholar
• Roher A E, Lovvenson J D, Clarke S, Wolkow C, Wang R, Cotter R J, Reardon I M, Zurcher-Neely H A, Heinrikson R L, Ball M J, Greenberg B D. Structural alteration in the peptide backbone of β-amyloid core protein may account for its deposition and stability in Alzheimer's disease. J Biol Chem 1993; 268: 3072–3083
   PubMed Web of Science ®Google Scholar
• Wisniewski H, Johnson A B, Raine C S, Kay W J, Terry R D. Senile plaques and cerebral amyloidosis in aged dogs. Lab Invest 1970; 23: 287–296
   PubMed Web of Science ®Google Scholar
• Cummings B, Su J, Cotman C, White R, Russell M. β-Amyloid accumulation in aged canine brain: a model of early plaque formation in Alzheimer's disease. Neurobiol Aging 1993; 14: 547–560
   PubMed Web of Science ®Google Scholar
• Russell M, Bobik J. M, White R G, Hou Y, Benjamin S A, Geddes J W. Age-specific onset of P-amyloid in Beagle brains. Neurobiol Aging 1996; 17: 269–273
   PubMed Web of Science ®Google Scholar
• Pappolla M A, Omar R A, Vinters H V. Image analysis microspectroscopy shows that neurons participate in the genesis of subset of early primitive (diffuse) senile plaques. Am J Pathol 1991; 139: 599–607
   PubMed Web of Science ®Google Scholar
• Wisniewski H M, Wegiel J, Wang K C, Kujawa M, Lach B. Ultrastructural studies of the cells forming amyloid fibers in classical plaques. Can J Neurol Sci 1989; 16: 535–542
   PubMed Web of Science ®Google Scholar
• Wisniewski H M, Wegiel J. Migration of perivascular cells into the neuropil and their involvement in P-amyloid plaque formation. Acta Neuropathol 1993; 85: 586–595
   PubMed Web of Science ®Google Scholar
• Wisniewski H M, Wegiel J. P-Amyloid formation by myocytes of leptomeningeal vessels. Acta Neuropathol 1994; 87: 233–241
   PubMed Web of Science ®Google Scholar
• Nakamura S, Nakayama H, Goto N, Ono-Ochikubo F, Sakakibara I, Yoshikawa Y. Histopathological studies on senile plaques and cerebral amyloid angiopathy in cynomolgus monkeys. Exp Anim 1995; 43: 711–718
   PubMed Web of Science ®Google Scholar
• Podlisny M B, Tolan D R, Selkoe D J. Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidos in Alzheimer's disease. Am J Pathol 1991; 138: 1423–1435
   PubMed Web of Science ®Google Scholar
• Selkoe D J, Bell D S, Podlisny M B, Price D L, Cork L C. Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease. Science 1987; 235: 873–877
   PubMed Web of Science ®Google Scholar
• Kuroki K, Uchida K, Kiatipattanasakul W, Nakamura S, Yamaguchi R, Nakayama H, Doi K, Tateyama S. Immunohistochemical detection of tau protein in various non-human animal brains. Neuropathology 1997; 17: 174–180
   Web of Science ®Google Scholar
• Gruys E. First workshop and clinic on neuropathology in geriatric dogs and cats. Wiesbaden, Germany, May 4–5., 1995. Amyloid Int J Exp Clin Invest 1995; 2: 280–283
   Google Scholar
• Shimada A, Kuwamura M, Awakura T, Umemura T, Takada K, Ohama E, Itakura C. Topographic relationship between senile plaques and cerebrovascular amyloidosis in the brain of aged dogs. J Vet Med Sci 1992; 54: 137–144
   PubMed Web of Science ®Google Scholar
• Prior R, D'Urso D, Frank R, Prikulis I, Pavlakovic G. Experimental deposition of Alzheimer amyloid P-protein in canine leptomenigeal vessels. NeuroReport 1995; 6: 1747–1751
   PubMed Web of Science ®Google Scholar
• Wegiel J, Wisniewski H M, Driewiatkowski J, Tarnawski M, Nowakowski J, Dziewiathowska A, Soltysiak Z. The origin of amyloid in cerebral vessels of aged dogs. Brain Research 1995; 705: 225–234
   PubMed Web of Science ®Google Scholar
• Cummings B J, Head E, Ruehl W, Milgram N W, Cotman C W. The canine as an animal model of human aging and dementia. Neurobiol Aging 1996; 17: 259–268
   PubMed Web of Science ®Google Scholar
• Giaccone G, Verga L, Finazzi M, Polio B, Tagliavini F, Frangione B, Bugiani O. Cerebral preamyloid deposits and congophilic angiopathy in aged dogs. Neurosci Lett 1990; 114: 178–183
   PubMed Web of Science ®Google Scholar
• Ishihara T, Gondo T, Takahashi M, Uchino F, Ikeda S, Allsop D, Imai K. Immunohistochemical and immunoelectron microscopical characterization of cerebrovascular and senile plaque amyloid in aged dogs brain. Brain Res 1991; 548: 196–205
   PubMed Web of Science ®Google Scholar
• Uchida K, Okuda R, Yamaguchi R, Tateyama S, Nakayama H, Goto N. Double-labeling immunohistochemical studies on canine senile plaques and cerebral amyloid angiopathy. J Vet Med Sci 1993; 55: 637–642
   PubMed Web of Science ®Google Scholar
• Uchida K, Yoshino T, Yamaguchi R, Tateyama S, Nakayama H, Goto N. Senile plaques and other senile changes in the brain of an aged American black bear. Vet Pathol 1993; 32: 412–414
   Web of Science ®Google Scholar
• Tekirian T, Cole G M, Russell M J, Yang F, Wekstein D R, Patel E, Snowdon D, Markesbery W R, Geddes J W. Carboxy terminal of P-amyloid deposits in aged human, canine and polar bear brains. Neuropathol Aging 1996; 17: 249–257
   PubMed Web of Science ®Google Scholar
• Nakamura S, Nakayama H, Kiatipattanasakul W, Uetsuka K, Uchida K, Goto N. Senile plaques in very aged cats. Acta Neuropathol 1996; 91: 437–439
   PubMed Web of Science ®Google Scholar
• Nakamura S, Tamaoka A, Sawamura N, Kiatipattanasakul W, Nakayama H, Shoji S, Yoshikawa Y, Doi K. Deposition of amyloid P protein (AP) subtypes [AP40 and Aβ42(43)] in canine senile plaques and cerebral amyloid angiopathy. Acta Neuropathol 1997; 94: 323–328
   PubMed Web of Science ®Google Scholar
• Shoji M, Kawarabayashi T, Sato M, Sasaki A, Saido T C, Matsubara E, Tomidokoro Y, Kanai M, Shizuka M, Ishiguro K, Ikeda M, Harigaya Y, Okamoto K, Hirai S. Age-related amyloid beta protein accumulation induces cellular death and macrophage activation in transgenic mice. J Pathol 2000; 191: 93–101
   PubMed Web of Science ®Google Scholar
• Emilien G, Maloteaux J M, Beyreuther K, Masters C L. Alzheimer disease: mouse models pave the way for therapeutic opportunities. Arch Neurol 2000; 57: 176–181
   PubMedGoogle Scholar
• Calhoun M E, Burgermeister P, Phinney A L, Stalder M, Tolnay M, Wiederhold K H, Abramowski D, Sturchler-Pierrat C, Sommer B, Staubenbiel M, Jucker M. Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid. Proc Natl Acad Sci USA 1999; 96: 14088–14093
   PubMed Web of Science ®Google Scholar
• Pappolla M A, Chyan Y J, Omar R A, Hsiao K, Perry G, Smith M A, Bozner P. Evidence of oxidative stress and in vivo, neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo. Am J Pathol 1998; 152: 871–877
   PubMed Web of Science ®Google Scholar
• Namba Y, Tomonaga M, Kawasaki H, Otomo E, Ikeda K. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and Kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res 1991; 541: 163–166
   PubMed Web of Science ®Google Scholar
• Uchida K, Kuroki K, Yoshino T, Yamaguchi R, Tateyama S. Immunohistochemical study of constituents other than p-protein in canine senile plaques and cerebral amyloid angiopathy. Acta Neuropathol 1997; 93: 277–284
   PubMed Web of Science ®Google Scholar
• Pitas R E, Boyles J K, Lee S H, Foss D, Mahley R W. Astrocytes synthesize apolipoprotein E and metabolize E-containing lipoproteins. Biochim Biophys Acta 1987; 917: 148–161
   PubMed Web of Science ®Google Scholar
• Beach T G, Walker R, McGree E. G. Patterns of gliosis in Alzheimer's disease and aging cerebrum. Glia 1989; 2: 420–436
   PubMed Web of Science ®Google Scholar
• Duffy P E, Rapport M, Graf L. Glial fibrillary acidic protein and Alzheimer-type senile dementia. Neurology 1980; 30: 778–782
   PubMed Web of Science ®Google Scholar
• Hansen L A, Armstrong D M, Terry R D. An im-munohistochemical quantification of fibrous astrocytes in the aging human cerebral cortex. Neurobiol Aging 1987; 8: 1–6
   PubMed Web of Science ®Google Scholar
• Mancardi G I, Liwnicz B H, Mandybur T T. Fibrous astrocytes in Alzheimer's disease and senile dementia of Alzheimer's type. Acta Neuropathol 1983; 61: 76–80
   PubMed Web of Science ®Google Scholar
• Schechter R, Yen S H, Terry R D. Fibrous astrocytes in senile dementia of the Alzheimer type. J Neuropathol Exp Neurol 1981; 40: 95–101
   PubMed Web of Science ®Google Scholar
• Adams I, Jones D G. Synaptic remodelling and astrocytic hypertrophy in rat cerebral cortex from early to late adulthood. Neurobiol Aging 1983; 3: 179–186
   Web of Science ®Google Scholar
• De la Roza C, Cano J, Reinoso-Suarez F. An electron microscopic study of astroglia and oligodendroglia in the lateral geniculate nucleus of aged rats. Mech Ageing Dev 1985; 29: 267–281
   PubMed Web of Science ®Google Scholar
• Geinisman Y, Bondareff W, Dodge J T. Hypertrophy of astroglial processes in the dentate gyrus of the senescent rat. Am JAnat 1978; 153: 537–544
   PubMedGoogle Scholar
• O'Kusky J, Colonnier M. Postnatal changes in the number of astrocytes oligodendrocytes and microglia in the visual cortex (area 17) of the macaque monkey: a stereologi-cal analysis in normal and monocularly deprived animals. Comp Neurol 1982; 210: 307–315
   PubMed Web of Science ®Google Scholar
• Shimada A, Kuwamura M, Awakura T, Umemura T, Itakura C. An Immunohistochemical and ultrastruc-tural study on age-related astrocytic gliosis in the central nervous system of dogs. J Vet Med Sci 1992; 54: 29–36
   PubMed Web of Science ®Google Scholar
• Borras D, Ferrer I, Pumarola M. Age-related changes in the brain of the dog. Vet Pathol 1999; 36: 202–211
   PubMed Web of Science ®Google Scholar
• Ando Y, Braennstroem T, Uchida K, Nyhlin N, Naesman B, Suhr O, Yamashita T, Olsson T, El Sahly M, Uchino M, Ando M. Histochemical detection of 4-hydroxynonenal protein in Alzheimer amyloid. J Neurol Sci 1998; 156: 172–176
   PubMed Web of Science ®Google Scholar
• Eisenhauer P B, Johnson R J, Wells J M, Davies T A, Fine R E. Toxicity of various amyloid beta peptide species in cultured human blood-brain barrier endothelial cells: increased toxicity of Dutch-type mutant. J Neurosci Res 2000; 60: 804–810
   PubMed Web of Science ®Google Scholar
• Linke R P. Highly sensitive diagnosis of amyloid and various amyloid syndromes using Congo red fluorescence. Virchows Arch 2000; 436: 439–448
   PubMed Web of Science ®Google Scholar
• Schultz C, Dehghani F, Hubbard G B, Thai D R, Struckhoff G, Braak E, Braak H. Filamentous tau pathology in nerve cells, astrocytes, and oligodendrocytes of aged baboons. J Neuropathol Exp Neurol 2000; 59: 39–52
   PubMed Web of Science ®Google Scholar
• Van de Kaa C A, Hoi P R, Huber J, Linke R P, Kooiker C J, Gruys E. Diagnosis 1of the type of amyloid in paraffin wax embedded tissue sections using antisera against human and animal amyloid proteins. Virchows Arch A Pathol Anat Histopathol 1986; 408: 649–664, 52
   PubMedGoogle Scholar
• Summers B A, Cummings J F, de Lahunta A. Neuropathology of ageing. Veterinary Neuropathology. Mosby-Year Book, St Louis 1995; 49–55
   Google Scholar
• Ferrer I, Pumarola M, Rivera R, Zujar M J, Cruz-Sanchez F, Vidal A. Primary central white matter degeneration in old doogs. Acta Neuropathol 1993; 86: 172–175
   PubMed Web of Science ®Google Scholar
• Jellinger K. Cerebrovascular amyloidosis with cerebral hemorrhage. J Neurol 1977; 214: 195–206
   PubMed Web of Science ®Google Scholar
• Lee S S, Stemmermann G N. Congophilic angiopathy and cerebral hemorrhage. Arch Pathol Med 1978; 102: 317–321
   PubMed Web of Science ®Google Scholar
• Vinters H V. Cerebral amyloid angiopathy: A critical review. Stroke 1987; 18: 311–324
   PubMed Web of Science ®Google Scholar
• Okazaki H, Reagan T J, Campbell R J. Clinicopatho-logical studies of primary cerebral amyloid angiopathy. Mayo Clin Prac 1979; 54: 22–31
   PubMed Web of Science ®Google Scholar
• Uchida K, Miyauchi Y, Nakayama H, Goto N. Amyloid angiopathy with cerebral hemorrhage and senile plaque in aged dogs. Jpn J Vet Sci 1960; 52: 605–611
   Google Scholar
• Wisniewski H M, Ghetti B, Terry R D. Neuritic (senile) plaques and filamentous changes in aged rhesus monkeys. J Neuropathol Exp Neurol 1973; 32: 566–584
   PubMed Web of Science ®Google Scholar
• Harada K, Krucke W, Mancardi J L, Mandybur T I. Alzheimer's tangles in sudanophilic leukodystrophy. Neurology 1988; 38: 55–59
   PubMed Web of Science ®Google Scholar
• Vinters H V, Fisher R S, Cornford M E, Mah V, Secor D L, De Rosa M J, Comair Y G, Peacock W J, Shields W D. Morphological substrates of infantile spasms: studies based on surgically resected cerebral tissue. Childs Nerv Syst 1992; 8: 8–17
   PubMed Web of Science ®Google Scholar
• Strittmatter W J, Saunders A M, Schmechel D, Periacak-Vance M, Enghild J, Salvesen G S, Roses A D. Apolipoprotein E: high-avidity binding to P-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer's disease. Proc Natl Acad Sci USA 1993; 90: 1977–1981
   PubMed Web of Science ®Google Scholar
• Ando Y, Nyhlin N, Suhr O, Holmgren G, Uchida K, El-Sahly M, Yamashita T, Terasaki H, Nakamura M, Uchino M, Ando M. Oxidative stress is found in amyloid deposits in systemic amyloidosis. Biochem Biophys Research Commun 1997; 232: 497–502
   PubMed Web of Science ®Google Scholar
• Uchida K, Szweda L I, Chae H Z, Stadtman E R. Immunohistochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes. Proc Natl Acad Sci 1993; 90: 8742–8746
   PubMed Web of Science ®Google Scholar
• Toyokuni S, Uchida K, Okamoto K, Hattori-Nakakuki Y, Hiai H, Stadtman E R. Formation of 4-hydroxy-2-nonenal modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate. Proc Natl Acad Sci 1994; 91: 2616–2620
   PubMed Web of Science ®Google Scholar
• Sayre L M, Zelasko D A, Harris P L, Perry G, Salomon R G, Smith M A. 4-Hydroxynonenal-derived advanced lipid peroxidation and products are increased in Alzheimer's disease. JNeurochem 1997; 68: 2092–2097
   PubMed Web of Science ®Google Scholar
• El-Agnaf O M, Bodies A M, Guthrie D J, Harriot P, Irvine G B. The N-terminal region of non-A beta component of Alzheimer's disease amyloid is responsible for its tendency to assume beta-sheet and aggregate to form fibrils. Eur J Biochem 1998; 258: 157–163
   PubMedGoogle Scholar
• Schubert D, Behl C, Lesley R, Brack A, Dargusch R, Sagara Y, Kimura H. Amyloid peptides are toxic via a common oxidative mechanism. Proc Natl Acad Sci 1995; 92: 1989–1993
   PubMed Web of Science ®Google Scholar
• McKee A C, Kosik K S, Kowall N W. Neuritic pathology and dementia in Alzheimer's disease. Ann Neurol 1991; 30: 156–165
   PubMed Web of Science ®Google Scholar
• Uchida K, Tani Y, Uetsuka K, Nakayama H, Goto N. Immunohistochemical studies on canine cerebral amyloid angiopathy and senile plaques. J Vet Med Sci 1992; 54: 659–667
   PubMed Web of Science ®Google Scholar