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Review Article

Potential clinical insights into microRNAs and their target genes in esophageal carcinoma

, &
Pages 629-636 | Received 21 May 2011, Accepted 22 Jul 2011, Published online: 29 Aug 2011

References

  • Banerjee HN, Verma M. (2009). Epigenetic mechanisms in cancer. Biomark Med 3:397–410.
  • Bohnsack MT, Czaplinski K, Gorlich D. (2004). Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. Rna 10:185–191.
  • Borchert GM, Lanier W, Davidson BL. (2006). RNA polymerase III transcribes human microRNAs. Nat Struct Mol Biol 13:1097–1101.
  • Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, Shiekhattar R. (2005). TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436:740–744.
  • Cho WC. (2010). MicroRNAs in cancer - from research to therapy. Biochim Biophys Acta 1805:209–217.
  • Dijckmeester WA, Wijnhoven BP, Watson DI, Leong MP, Michael MZ, Mayne GC, Bright T, Astill D, Hussey DJ. (2009). MicroRNA-143 and -205 expression in neosquamous esophageal epithelium following Argon plasma ablation of Barrett’s esophagus. j Gastrointest Surg 13:846–853.
  • Elmén J, Lindow M, Schütz S, Lawrence M, Petri A, Obad S, Lindholm M, Hedtjärn M, Hansen HF, Berger U, Gullans S, Kearney P, Sarnow P, Straarup EM, Kauppinen S. (2008). LNA-mediated microRNA silencing in non-human primates. Nature 452:896–899.
  • Esteller M. (2008). Epigenetics in cancer. n Engl j Med 358:1148–1159.
  • Fassan M, Mescoli C, Volinia S, Pizzi M, Palatini J, Baffa R, Clemente R, Rizzetto C, Croce C, Zaninotto G, Ancona E, Rugge M (2010) Micrornas are deregulated in Barrett’s carcinogenesis. Digestive and Liver Disease 42: S146
  • Feber A, Xi L, Luketich JD, Pennathur A, Landreneau RJ, Wu M, Swanson SJ, Godfrey TE, Litle VR. (2008). MicroRNA expression profiles of esophageal cancer. J Thorac Cardiovasc Surg 135:255–60. discussion 260.
  • Garofalo M, Croce CM. (2011). microRNAs: Master regulators as potential therapeutics in cancer. Annu Rev Pharmacol Toxicol 51:25–43.
  • Garzon R, Calin GA, Croce CM. (2009). MicroRNAs in Cancer. Annu Rev Med 60:167–179.
  • Garzon R, Marcucci G, Croce CM. (2010). Targeting microRNAs in cancer: rationale, strategies and challenges. Nat Rev Drug Discov 9:775–789.
  • Guo Y, Chen Z, Zhang L, Zhou F, Shi S, Feng X, Li B, Meng X, Ma X, Luo M, Shao K, Li N, Qiu B, Mitchelson K, Cheng J, He J. (2008). Distinctive microRNA profiles relating to patient survival in esophageal squamous cell carcinoma. Cancer Res 68:26–33.
  • Harata K, Ishiguro H, Kuwabara Y, Kimura M, Mitsui A, Ogawa R, Katada T, Tanaka T, Shiozaki M, Fujii Y. (2010). MicroRNA-34b has an oncogenic role in esophageal squamous cell carcinoma. Oncol Lett 1:685–689
  • Harris CC. (2010) Interweaving microRNA, inflammatory cytokine and p53 pathways in human cancer. EurJ Canc, Supplement 8:7–8
  • Hiyoshi Y, Kamohara H, Karashima R, Sato N, Imamura Y, Nagai Y, Yoshida N, Toyama E, Hayashi N, Watanabe M, Baba H. (2009). MicroRNA-21 regulates the proliferation and invasion in esophageal squamous cell carcinoma. Clin Cancer Res 15:1915–1922.
  • Hong L, Han Y, Zhang H, Li M, Gong T, Sun L, Wu K, Zhao Q, Fan D. (2010). The prognostic and chemotherapeutic value of miR-296 in esophageal squamous cell carcinoma. Ann Surg 251:1056–1063.
  • Hu Y, Correa AM, Hoque A, Guan B, Ye F, Huang J, Swisher SG, Wu TT, Ajani JA, Xu XC. (2011). Prognostic significance of differentially expressed miRNAs in esophageal cancer. Int j Cancer 128:132–143.
  • Hummel R, Hussey DJ, Michael MZ, Haier J, Bruewer M, Senninger N, Watson DI. (2011). MiRNAs and their association with locoregional staging and survival following surgery for esophageal carcinoma. Ann Surg Oncol 18:253–260.
  • Inoue N, Isomoto H, Matsushima K, Hayashi T, Kunizaki M, Hidaka S, Machida H, Mitsutake N, Nanashima A, Takeshima F, Nakayama T, Ohtsuru A, Nakashima M, Nagayasu T, Yamashita S, Nakao K, Kohno S. (2010) Down-regulation of microRNA 10a expression in esophageal squamous cell carcinoma cells. Oncol Lett 1:527–531
  • Kan T, Meltzer SJ. (2009). MicroRNAs in Barrett’s esophagus and esophageal adenocarcinoma. Curr Opin Pharmacol 9:727–732.
  • Kan T, Sato F, Ito T, Matsumura N, David S, Cheng Y, Agarwal R, Paun BC, Jin Z, Olaru AV, Selaru FM, Hamilton JP, Yang J, Abraham JM, Mori Y, Meltzer SJ. (2009). The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim. Gastroenterology 136:1689–1700.
  • Kano M, Seki N, Kikkawa N, Fujimura L, Hoshino I, Akutsu Y, Chiyomaru T, Enokida H, Nakagawa M, Matsubara H. (2010). miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma. Int j Cancer 127:2804–2814.
  • Kim VN. (2005). MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol 6:376–385.
  • Kim YK, Kim VN. (2007). Processing of intronic microRNAs. Embo J 26:775–783.
  • Kimura S, Naganuma S, Susuki D, Hirono Y, Yamaguchi A, Fujieda S, Sano K, Itoh H. (2010). Expression of microRNAs in squamous cell carcinoma of human head and neck and the esophagus: miR-205 and miR-21 are specific markers for HNSCC and ESCC. Oncol Rep 23:1625–1633.
  • Kitade Y, Akao Y. (2010). MicroRNAs and their therapeutic potential for human diseases: microRNAs, miR-143 and -145, function as anti-oncomirs and the application of chemically modified miR-143 as an anti-cancer drug. j Pharmacol Sci 114:276–280.
  • Kota J, Chivukula RR, O’Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, Mendell JT. (2009). Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137:1005–1017.
  • Lee KH, Goan YG, Hsiao M, Lee CH, Jian SH, Lin JT, Chen YL, Lu PJ. (2009). MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer. Exp Cell Res 315:2529–2538.
  • Lee Y, Kim M, Han J, Yeom KH, Lee S, Baek SH, Kim VN. (2004). MicroRNA genes are transcribed by RNA polymerase II. Embo J 23:4051–4060.
  • Luthra R, Singh RR, Luthra MG, Li YX, Hannah C, Romans AM, Barkoh BA, Chen SS, Ensor J, Maru DM, Broaddus RR, Rashid A, Albarracin CT. (2008). MicroRNA-196a targets annexin A1: a microRNA-mediated mechanism of annexin A1 downregulation in cancers. Oncogene 27:6667–6678.
  • Lv J, Cao XF, Zhu B, Ji L, Tao L, Wang DD. (2009). Effect of neoadjuvant chemoradiotherapy on prognosis and surgery for esophageal carcinoma. World j Gastroenterol 15:4962–4968.
  • Maru DM, Singh RR, Hannah C, Albarracin CT, Li YX, Abraham R, Romans AM, Yao H, Luthra MG, Anandasabapathy S, Swisher SG, Hofstetter WL, Rashid A, Luthra R. (2009). MicroRNA-196a is a potential marker of progression during Barrett’s metaplasia-dysplasia-invasive adenocarcinoma sequence in esophagus. Am j Pathol 174:1940–1948.
  • Mathé EA, Nguyen GH, Bowman ED, Zhao Y, Budhu A, Schetter AJ, Braun R, Reimers M, Kumamoto K, Hughes D, Altorki NK, Casson AG, Liu CG, Wang XW, Yanaihara N, Hagiwara N, Dannenberg AJ, Miyashita M, Croce CM, Harris CC. (2009). MicroRNA expression in squamous cell carcinoma and adenocarcinoma of the esophagus: associations with survival. Clin Cancer Res 15:6192–6200.
  • Matsushima K, Isomoto H, Inoue N, Nakayama T, Fukuda M, Akazawa Y, Yamaguchi N, Ohnita K, Takeshima F, Nakao K. (2010a) Involvement of micrornas in the invasion of esophageal cancer cells. AnnOncol 21: viii48
  • Matsushima K, Isomoto H, Kohno S, Nakao K. (2010b). MicroRNAs and esophageal squamous cell carcinoma. Digestion 82:138–144.
  • Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, Spizzo R, Fernandez AF, Davalos V, Villanueva A, Montoya G, Yamamoto H, Schwartz S Jr, Esteller M. (2010). A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. Cancer Cell 18:303–315.
  • Merritt WM, Bar-Eli M, Sood AK. (2010). The dicey role of Dicer: implications for RNAi therapy. Cancer Res 70:2571–2574.
  • Mori Y, Ishiguro H, Kuwabara Y, Kimura M, Mitsui A, Ogawa R, Katada T, Harata K, Tanaka T, Shiozaki M, Fujii Y. (2009). MicroRNA-21 induces cell proliferation and invasion in esophageal squamous cell carcinoma. Mol Med Report 2:235–239.
  • Nguyen GH, Schetter AJ, Chou DB, Bowman ED, Zhao R, Hawkes JE, Mathé EA, Kumamoto K, Zhao Y, Budhu A, Hagiwara N, Wang XW, Miyashita M, Casson AG, Harris CC. (2010). Inflammatory and microRNA gene expression as prognostic classifier of Barrett’s-associated esophageal adenocarcinoma. Clin Cancer Res 16:5824–5834.
  • Ogawa R, Ishiguro H, Kuwabara Y, Kimura M, Mitsui A, Katada T, Harata K, Tanaka T, Fujii Y. (2009). Expression profiling of micro-RNAs in human esophageal squamous cell carcinoma using RT-PCR. Med Mol Morphol 42:102–109.
  • Ohashi S, Kalman RA, Natsuizaka M, Grugan KD, Stairs DB, Kalabis J, Andl C, Yang Y, Rhoades B, Pear WS, Katz JP, Nakagawa H. (2009) Genetic Ablation of the notch signaling promotes TGF-(β)-induced epithelial-mesenchymal transition involving posttranscriptional regulation of ZEB1 and ZEB2 By MicroRNA-200 family members. Gastroenterol 136:A54
  • Ohta M, Mimori K, Fukuyoshi Y, Kita Y, Motoyama K, Yamashita K, Ishii H, Inoue H, Mori M. (2008). Clinical significance of the reduced expression of G protein gamma 7 (GNG7) in oesophageal cancer. Br j Cancer 98:410–417.
  • Petrocca F, Lieberman J. (2009). Micromanipulating cancer: microRNA-based therapeutics? rna Biol 6:335–340.
  • Sharma S, Kelly TK, Jones PA. (2010). Epigenetics in cancer. Carcinogenesis 31:27–36.
  • Smith CM, Watson DI, Michael MZ, Hussey DJ. (2010). MicroRNAs, development of Barrett’s esophagus, and progression to esophageal adenocarcinoma. World j Gastroenterol 16:531–537.
  • Takashima N, Ishiguro H, Kuwabara Y, Kimura M, Haruki N, Ando T, Kurehara H, Sugito N, Mori R, Fujii Y. (2006). Expression and prognostic roles of PABPC1 in esophageal cancer: correlation with tumor progression and postoperative survival. Oncol Rep 15:667–671.
  • Tian Y, Luo A, Cai Y, Su Q, Ding F, Chen H, Liu Z. (2010). MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines. j Biol Chem 285:7986–7994.
  • Tischoff I, Tannapfel A. (2008). Barrett’s esophagus: can biomarkers predict progression to malignancy? Expert Rev Gastroenterol Hepatol 2:653–663.
  • Tsuchiya S, Fujiwara T, Sato F, Shimada Y, Tanaka E, Sakai Y, Shimizu K, Tsujimoto G. (2011). MicroRNA-210 regulates cancer cell proliferation through targeting fibroblast growth factor receptor-like 1 (FGFRL1). j Biol Chem 286:420–428.
  • Van Baal J, Vleggaar FP, Siersema PD. (2009) Are MicroRNA-215 and 199a-5p potentially useful biomarkers in the development of Barrett’s esophagus and esophageal adenocarcinoma? Gastroenterol 136:A304
  • Wang J, Sui M, Fan W. (2010). Nanoparticles for tumor targeted therapies and their pharmacokinetics. Curr Drug Metab 11:129–141.
  • Wang V, Wu W. (2009). MicroRNA-based therapeutics for cancer. Biodrugs 23:15–23.
  • Wijnhoven BP, Hussey DJ, Watson DI, Tsykin A, Smith CM, Michael MZ; South Australian Oesophageal Research Group. (2010). MicroRNA profiling of Barrett’s oesophagus and oesophageal adenocarcinoma. Br j Surg 97:853–861.
  • Wu BL, Xu LY, Du ZP, Liao LD, Zhang HF, Huang Q, Fang GQ, Li EM. (2011). MiRNA profile in esophageal squamous cell carcinoma: downregulation of miR-143 and miR-145. World j Gastroenterol 17:79–88.
  • Wu W. (2011). Modulation of microRNAs for potential cancer therapeutics. Methods Mol Biol 676:59–70.
  • Yang H, Gu J, Wang KK, Zhang W, Xing J, Chen Z, Ajani JA, Wu X. (2009). MicroRNA expression signatures in Barrett’s esophagus and esophageal adenocarcinoma. Clin Cancer Res 15:5744–5752.
  • Ye Y, Wang KK, Gu J, Yang H, Lin J, Ajani JA, Wu X. (2008). Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. Cancer Prev Res (Phila) 1:460–469.
  • Yoshino M, Ishiwata T, Watanabe M, Matsunobu T, Komine O, Ono Y, Yamamoto T, Fujii T, Matsumoto K, Tokunaga A, Naito Z. (2007). Expression and roles of keratinocyte growth factor and its receptor in esophageal cancer cells. Int j Oncol 31:721–728.
  • Yuan Y, Gong DJ, Liu XH, Lu FL. (2010). MiR-203 inhibits proliferation and invasion of esophageal squamous cell carcinoma. Academic Journal of Second Military Medical University 31: 818–821.
  • Yuan Y, Zeng ZY, Liu XH, Gong DJ, Tao J, Cheng HZ, Huang SD. (2011). MicroRNA-203 inhibits cell proliferation by repressing ?Np63 expression in human esophageal squamous cell carcinoma. bmc Cancer 11:57.
  • Zhang H, Li M, Han Y, Hong L, Gong T, Sun L, Zheng X. (2010). Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma. Dig Dis Sci 55:2545–2551.

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