Urinary mRNA expression of CCN2/CCN3 as a noninvasive marker for monitoring glomerular structure changes in nondiabetic chronic kidney disease

References

• Bramham K, Mistry HD, Poston L, Chappell LC, Thompson AJ. (2009). The non-invasive biopsy–will urinary proteomics make the renal tissue biopsy redundant? QJM 102:523–538.
   PubMed Web of Science ®Google Scholar
• Caglar K, Yilmaz MI, Sonmez A, Cakir E, Kaya A, Acikel C, Eyileten T, Yenicesu M, Oguz Y, Bilgi C, Oktenli C, Vural A, Zoccali C. (2006). ADMA, proteinuria, and insulin resistance in non-diabetic stage I chronic kidney disease. Kidney Int 70:781–787.
   PubMed Web of Science ®Google Scholar
• Cicha I, Goppelt-Struebe M. (2009). Connective tissue growth factor: context-dependent functions and mechanisms of regulation. Biofactors 35:200–208.
   PubMed Web of Science ®Google Scholar
• Colburn WA. (2003). Biomarkers in drug discovery and development: from target identification through drug marketing. J Clin Pharmacol 43:329–341.
   PubMed Web of Science ®Google Scholar
• Colucci G, Floege J, Schena FP. (2006). The urinary sediment beyond light microscopical examination. Nephrol Dial Transplant 21:1482–1485.
   PubMed Web of Science ®Google Scholar
• Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, Van Lente F, Levey AS. (2007). Prevalence of chronic kidney disease in the United States. JAMA 298:2038–2047.
   PubMed Web of Science ®Google Scholar
• de Jong PE, Gansevoort RT. (2010). Albuminuria in non-primary renal disease: risk marker rather than risk factor. Nephrol Dial Transplant 25:656–658.
   PubMed Web of Science ®Google Scholar
• Dendooven A, Gerritsen KG, Nguyen TQ, Kok RJ, Goldschmeding R. (2011). Connective tissue growth factor (CTGF/CCN2) ELISA: a novel tool for monitoring fibrosis. Biomarkers 16:289–301.
   PubMed Web of Science ®Google Scholar
• El Nahas AM, Bello AK. (2005). Chronic kidney disease: the global challenge. Lancet 365:331–340.
   PubMed Web of Science ®Google Scholar
• Goumenos DS, Tsakas S, El Nahas AM, Alexandri S, Oldroyd S, Kalliakmani P, Vlachojannis JG. (2002). Transforming growth factor-beta(1) in the kidney and urine of patients with glomerular disease and proteinuria. Nephrol Dial Transplant 17:2145–2152.
   PubMed Web of Science ®Google Scholar
• Gupta S, Clarkson MR, Duggan J, Brady HR. (2000). Connective tissue growth factor: potential role in glomerulosclerosis and tubulointerstitial fibrosis. Kidney Int 58:1389–1399.
   PubMed Web of Science ®Google Scholar
• Huang Y, Border WA, Yu L, Zhang J, Lawrence DA, Noble NA. (2008). A PAI-1 mutant, PAI-1R, slows progression of diabetic nephropathy. J Am Soc Nephrol 19:329–338.
   PubMed Web of Science ®Google Scholar
• Leask A. (2012). CCN3: a novel anti-fibrotic treatment in end-stage renal disease? J Cell Commun Signal 6:115–116.
   PubMed Web of Science ®Google Scholar
• Li B, Hartono C, Ding R, Sharma VK, Ramaswamy R, Qian B, Serur D, Mouradian J, Schwartz JE, Suthanthiran M. (2001). Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine. N Engl J Med 344:947–954.
   PubMed Web of Science ®Google Scholar
• Liu BC, Huang HQ, Luo DD, Ma KL, Liu DG, Liu H. (2006). Connective tissue growth factor is associated with the early renal hypertrophy in uninephrectomized diabetic rats. Chin Med J 119:1010–1016.
   PubMed Web of Science ®Google Scholar
• Ma YC, Zuo L, Chen JH, Luo Q, Yu XQ, Li Y, Xu JS, Huang SM, Wang LN, Huang W, Wang M, Xu GB, Wang HY. (2006). Modified glomerular filtration rate estimating equation for Chinese patients with chronic kidney disease. J Am Soc Nephrol 17:2937–2944.
   PubMed Web of Science ®Google Scholar
• Macisaac RJ, Jerums G. (2011). Diabetic kidney disease with and without albuminuria. Curr Opin Nephrol Hypertens 20:246–257.
   PubMed Web of Science ®Google Scholar
• Riser BL, Cortes P, DeNichilo M, Deshmukh PV, Chahal PS, Mohammed AK, Yee J, Kahkonen D. (2003). Urinary CCN2 (CTGF) as a possible predictor of diabetic nephropathy: preliminary report. Kidney Int 64:451–458.
   PubMed Web of Science ®Google Scholar
• Riser BL, Najmabadi F, Perbal B, Peterson DR, Rambow JA, Riser ML, Sukowski E, Yeger H, Riser SC. (2009). CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease. Am J Pathol 174:1725–1734.
   PubMed Web of Science ®Google Scholar
• Sato Y, Wharram BL, Lee SK, Wickman L, Goyal M, Venkatareddy M, Chang JW, Wiggins JE, Lienczewski C, Kretzler M, Wiggins RC. (2009). Urine podocyte mRNAs mark progression of renal disease. J Am Soc Nephrol 20:1041–1052.
   PubMed Web of Science ®Google Scholar
• Scheckner B, Peyser A, Rube J, Tarapore F, Frank R, Vento S, Hoffman C, Valderrama E, Charney D, Goilav B, Trachtman H. (2009). Diagnostic yield of renal biopsies: a retrospective single center review. BMC Nephrol 10:11.
   PubMed Web of Science ®Google Scholar
• Szeto CC, Chan RW, Lai KB, Szeto CY, Chow KM, Li PK, Lai FM. (2005a). Messenger RNA expression of target genes in the urinary sediment of patients with chronic kidney diseases. Nephrol Dial Transplant 20:105–113.
   PubMed Web of Science ®Google Scholar
• Szeto CC, Lai KB, Chow KM, Szeto CY, Yip TW, Woo KS, Li PK, Lai FM. (2005b). Messenger RNA expression of glomerular podocyte markers in the urinary sediment of acquired proteinuric diseases. Clin Chim Acta 361:182–190.
   PubMed Web of Science ®Google Scholar
• Szeto CC, Chow KM, Lai KB, Szeto CY, Chan RW, Kwan BC, Chung KY, Li PK, Lai FM. (2006). mRNA expression of target genes in the urinary sediment as a noninvasive prognostic indicator of CKD. Am J Kidney Dis 47:578–586.
   PubMed Web of Science ®Google Scholar
• Urbschat A, Obermüller N, Haferkamp A. (2011). Biomarkers of kidney injury. Biomarkers 16 Suppl 1:S22–S30.
   PubMed Web of Science ®Google Scholar
• van Roeyen CR, Eitner F, Scholl T, Boor P, Kunter U, Planque N, Gröne HJ, Bleau AM, Perbal B, Ostendorf T, Floege J. (2008). CCN3 is a novel endogenous PDGF-regulated inhibitor of glomerular cell proliferation. Kidney Int 73:86–94.
   PubMed Web of Science ®Google Scholar
• Zhang L, Wang F, Wang L, Wang W, Liu B, Liu J, Chen M, He Q, Liao Y, Yu X, Chen N, Zhang JE, Hu Z, Liu F, Hong D, Ma L, Liu H, Zhou X, Chen J, Pan L, Chen W, Wang W, Li X, Wang H. (2012). Prevalence of chronic kidney disease in China: a cross-sectional survey. Lancet 379:815–822.
   PubMed Web of Science ®Google Scholar
• Zheng M, Lv LL, Ni J, Ni HF, Li Q, Ma KL, Liu BC. (2011). Urinary podocyte-associated mRNA profile in various stages of diabetic nephropathy. PLoS ONE 6:e20431.
   PubMed Web of Science ®Google Scholar
• Zheng M, Lv LL, Cao YH, Zhang JD, Wu M, Ma KL, Phillips AO, Liu BC. (2012). Urinary mRNA markers of epithelial-mesenchymal transition correlate with progression of diabetic nephropathy. Clin Endocrinol (Oxf) 76:657–664.
   PubMed Web of Science ®Google Scholar