269
Views
9
CrossRef citations to date
0
Altmetric
Research Article

Serum autotaxin levels correlate with hepatic dysfunction and severity in postoperative biliary atresia

, , , , &
Pages 89-94 | Received 26 Sep 2014, Accepted 01 Dec 2014, Published online: 24 Dec 2014

References

  • A-Kader HH, Abdel-Hameed A, Al-Shabrawi M, et al. (2003). Is biliary atresia an autoimmune disease? Eur J Gastroenterol Hepatol 15:447.
  • Davenport M. (2012). Biliary atresia: clinical aspects. Semin Pediatr Surg 21:175–84
  • Fotopoulou S, Oikonomou N, Grigorieva E, et al. (2010). ATX expression and LPA signalling are vital for the development of the nervous system. Dev Biol 339:451–64
  • Gressner AM, Weiskirchen R. (2006). Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets. J Cell Mol Med 10:76–99
  • Hartley JL, Davenport M, Kelly DA. (2009). Biliary atresia. Lancet 374:1704–13
  • Ikeda H, Yatomi Y, Yanase M, et al. (1998). Effects of lysophosphatidic acid on proliferation of stellate cells and hepatocytes in culture. Biochem Biophys Res Commun 248:436–40
  • Iwasawa Y, Fujii T, Nagamatsu T, et al. (2009). Expression of autotaxin, an ectoenzyme that produces lysophosphatidic acid, in human placenta. Am J Reprod Immunol 62:90–5
  • Jansen S, Andries M, Vekemans K, et al. (2009). Rapid clearance of the circulating metastatic factor autotaxin by the scavenger receptors of liver sinusoidal endothelial cells. Cancer Lett 284:216–21
  • Muro H, Shirasawa H, Kosugi I, Nakamura S. (1993). Defect of Fc receptors and phenotypical changes in sinusoidal endothelial cells in human liver cirrhosis. Am J Pathol 143:105–20
  • Nakagawa H, Ikeda H, Nakamura K, et al. (2011). Autotaxin as a novel serum marker of liver fibrosis. Clin Chim Acta 412:1201–6
  • Nakasaki T, Tanaka T, Okudaira S, et al. (2008). Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions. Am J Pathol 173:1566–76
  • Pleli T, Martin D, Kronenberger B, et al. (2014). Serum autotaxin is a parameter for the severity of liver cirrhosis and overall survival in patients with liver cirrhosis – a prospective cohort study. PLoS One 9:e103532
  • Stefan C, Gijsbers R, Stalmans W, Bollen M. (1999). Differential regulation of the expression of nucleotide pyrophosphatases/phosphodiesterases in rat liver. Biochim Biophys Acta 1450:45–52
  • Stracke ML, Krutzsch HC, Unsworth EJ, et al. (1992). Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein. J Biol Chem 267:2524–9
  • Stracke ML, Clair T, Liotta LA. (1997). Autotaxin, tumor motility-stimulating exophosphodiesterase. Adv Enzyme Regul 37:135–44
  • Tanaka M, Okudaira S, Kishi Y, et al. (2006). Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid. J Biol Chem 281:25822–30
  • Tokumura A, Majima E, Kariya Y, et al. (2002). Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase. J Biol Chem 277:39436–42
  • van Meeteren LA, Ruurs P, Stortelers C, et al. (2006). Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Mol Cell Biol 26:5015–22
  • Wai CT, Greenson JK, Fontana RJ, et al. (2003). A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 38:518–26
  • Wallace K, Burt AD, Wright MC. (2008). Liver fibrosis. Biochem J 411:1–18
  • Watanabe N, Ikeda H, Nakamura K, et al. (2007a). Both plasma lysophosphatidic acid and serum autotaxin levels are increased in chronic hepatitis C. J Clin Gastroenterol 41:616–23
  • Watanabe N, Ikeda H, Nakamura K, et al. (2007b). Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity. Life Sci 81:1009–15
  • Wu JM, Xu Y, Skill NJ, et al. (2010). Autotaxin expression and its connection with the TNF-alpha-NF-kappaB axis in human hepatocellular carcinoma. Mol Cancer 31:9:71
  • Yamaoka K, Nouchi T, Marumo F, Satoc C. (1993). Alpha-smooth-muscle actin expression in normal and fibrotic human livers. Dig Dis Sci 38:1473–9
  • Yuelling LM, Fuss B. (2008). Autotaxin (ATX): a multi-functional and multi-modular protein possessing enzymatic lysoPLD activity and matricellular properties. Biochim Biophys Acta 1781:525–30

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.