Gene expression in the brain during reovirus encephalitis

References

• Beckham JD, Goody RJ, Clarke P, Bonny C, Tyler KL. (2007). Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase. J Virol 81:6984–6992.
   Google Scholar
• Beckham JD, Tuttle K, Tyler KL. (2009). Reovirus activates transforming growth factor beta and bone morphogenetic protein signaling pathways in the central nervous system that contribute to neuronal survival following infection. J. Virol 83:5035–5045.
   Google Scholar
• Bigger CB, Guerra B, Brasky KM, Hubbard G, Beard MR, Luxon BA, Lemon SM, Lanford RE. (2004). Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees. J. Virol 78:13779–13792.
   PubMed Web of Science ®Google Scholar
• Bordignon J, Probst CM, Mosimann AL, Pavoni DP, Stella V, Buck GA, Satproedprai N, Fawcett P, Zanata SM, de Noronha L, Krieger MA, Duarte Dos Santos CN. (2008). Expression profile of interferon stimulated genes in central nervous system of mice infected with dengue virus type-1. Virology 377:319–329.
   Google Scholar
• Bourne N, Scholle F, Silva MC, Rossi SL, Dewsbury N, Judy B, De Aguiar JB, Leon MA, Estes DM, Fayzulin R, Mason PW. (2007). Early production of type I interferon during West Nile virus infection: role for lymphoid tissues in IRF3-independent interferon production. J. Virol 81:9100–9108.
   Google Scholar
• Clarke P, Beckham JD, Leser JS, Hoyt CC, Tyler KL. (2009). Fas-mediated apoptotic signaling in the mouse brain following reovirus infection. J. Virol 83:6161–6170.
   Google Scholar
• Clarke P, DeBiasi RL, Meintzer SM, Robinson BA, Tyler KL. (2005). Inhibition of NF-kappa B activity and cFLIP expression contribute to viral-induced apoptosis. Apoptosis 10:513–524.
   Google Scholar
• Clarke P, Meintzer SM, Moffitt LA, Tyler KL. (2003). Two distinct phases of virus-induced nuclear factor kappa B regulation enhance tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in virus-infected cells. J. Biol. Chem 278:18092–18100.
   Google Scholar
• Clarke P, Meintzer SM, Wang Y, Moffitt LA, Richadson-Burns SM, Johnson GL, Tyler KL. (2004). JNK regulates the release of proapoptotic mitochondrial factors in reovirus-infected cells. J. Virol 78:13132–13138.
   PubMed Web of Science ®Google Scholar
• Clarke P, Meintzer SM, Widmann C, Johnson GL, Tyler KL. (2001). Reovirus infection activates JNK and the JNK-dependent transcription factor c-Jun. J. Virol 75:11275–11283.
   Google Scholar
• Connolly JL, Rodgers SE, Clarke P, Ballard DW, Kerr LD, Tyler KL, Dermody TS. (2000). Reovirus-induced apoptosis requires activation of transcription factor NF-kappaB. J. Virol 74:2981–2989.
   PubMed Web of Science ®Google Scholar
• D'Souza S, Xin H, Walter S, Choubey D. (2001). The gene encoding p202, an interferon-inducible negative regulator of the p53 tumor suppressor, is a target of p53-mediated transcriptional repression. J. Biol. Chem 276:298–305.
   PubMedGoogle Scholar
• Danthi P, Coffey CM, Parker JS, Abel TW, Dermody TS. (2008). Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domain. PLoS. Pathog 4:e1000248.
   Google Scholar
• DeBiasi RL, Clarke P, Meintzer SM, Jotte R, Kleinschmidt-Demasters BK, Johnson GL, Tyler KL. (2003). Reovirus-induced alteration in expression of apoptosis and DNA repair genes with potential roles in viral pathogenesis. J. Virol 77:8934–8947.
   Google Scholar
• Delhaye S, Paul S, Blakqori G, Minet M, Weber F, Staeheli P, Michiels T. (2006). Neurons produce type I interferon during viral encephalitis. Proc. Natl. Acad. Sci. U. S. A 103:7835–7840.
   PubMedGoogle Scholar
• Flames N, Hobert O. (2009). Gene regulatory logic of dopamine neuron differentiation. Nature, 458:885–889.
   Google Scholar
• Gentleman: RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini MJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J. (2004). Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5: R80.
   PubMed Web of Science ®Google Scholar
• Goody RJ, Beckham JD, Rubtsova K, Tyler KL. (2007). JAK-STAT signaling pathways are activated in the brain following reovirus infection. J. NeuroVirol 13:373–383.
   PubMed Web of Science ®Google Scholar
• Ho Sui SJ, Mortimer JR, Arenillas DJ, Brumm J, Walsh CJ, Kennedy BP, Wasserman WW. (2005). oPOSSUM: identification of over-represented transcription factor binding sites in co-expressed genes. Nucleic Acids Res 33, 3154–3164.
   PubMedGoogle Scholar
• Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, Speed TP. (2003). Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4:249–264.
   PubMed Web of Science ®Google Scholar
• Johansson C, Wetzel JD, He J, Mikacenic C, Dermody TS, Kelsall BL. (2007). Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus. J. Exp. Med 204:1349–1358.
   Web of Science ®Google Scholar
• Johnston C, Jiang W, Chu T, Levine B. (2001). Identification of genes involved in the host response to neurovirulent alphavirus infection. J. Virol 75:10431–10445.
   Google Scholar
• Kajaste-Rudnitski A, Mashimo T, Frenkiel MP, Guenet JL, Lucas M, Despres P. (2006). The 2′,5′-oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells. J. Biol. Chem 281:4624–4637.
   Google Scholar
• Knapp S, Yee LJ, Frodsham AJ, Hennig BJ, Hellier S, Zhang L, Wright M, Chiaramonte M, Graves M, Thomas HC, Hill AV, Thursz MR. (2003). Polymorphisms in interferon-induced genes and the outcome of hepatitis C virus infection: roles of MxA, OAS-1 and PKR. Genes Immun 4:411–419.
   PubMed Web of Science ®Google Scholar
• Kominsky DJ, Bickel RJ, Tyler KL. (2002). Reovirus-induced apoptosis requires both death receptor- and mitochondrial-mediated caspase-dependent pathways of cell death. Cell Death. Differ 9:926–933.
   Google Scholar
• Koterski J, Twenhafel N, Porter A, Reed DS, Martino-Catt S, Sobral B, Crasta O, Downey T, DaSilva L. (2007). Gene expression profiling of nonhuman primates exposed to aerosolized Venezuelan equine encephalitis virus. FEMS Immunol. Med. Microbiol 51:462–472.
   Google Scholar
• Malathi K, Dong B, Gale M Jr, Silverman RH. (2007). Small self-RNA generated by RNase L amplifies antiviral innate immunity. Nature, 448:816–819.
   PubMed Web of Science ®Google Scholar
• Muller U, Steinhoff U, Reis LF, Hemmi S, Pavlovic J, Zinkernagel RM, Aguet M. (1994). Functional role of type I and type II interferons in antiviral defense. Science 264:1918–1921.
   PubMed Web of Science ®Google Scholar
• O'Donnell SM, Hansberger MW, Connolly JL, Chappell JD, Watson MJ, Pierce JM, Wetzel JD, Han W, Barton ES, Forrest JC, Valyi-Nagy T, Yull FE, Blackwell TS, Rottman JN, Sherry B, Dermody TS. (2005). Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease. J. Clin. Invest 115:2341–2350.
   PubMedGoogle Scholar
• O'Donnell SM, Holm GH, Pierce JM, Tian B, Watson MJ, Chari RS, Ballard DW, Brasier AR, Dermody TS. (2006). Identification of an NF-kappaB-dependent gene network in cells infected by mammalian reovirus. J. Virol 80:1077–1086.
   PubMed Web of Science ®Google Scholar
• Oberhaus SM, Smith RL, Clayton GH, Dermody TS, Tyler KL. (1997). Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis. J. Virol 71:2100–2106.
   Google Scholar
• Poggioli GJ, DeBiasi RL, Bickel R, Jotte R, Spalding A, Johnson GL, Tyler KL. (2002). Reovirus-induced alterations in gene expression related to cell cycle regulation. J. Virol 76:2585–2594.
   Google Scholar
• Randall RE, Goodbourn S. (2008). Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. J. Gen. Virol 89:1–47.
   PubMed Web of Science ®Google Scholar
• Richardson-Burns SM, Kominsky DJ, Tyler KL. (2002). Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors. J. NeuroVirol 8:365–380.
   PubMed Web of Science ®Google Scholar
• Ryman KD, Klimstra WB, Nguyen KB, Biron CA, Johnston RE. (2000). Alpha/beta interferon protects adult mice from fatal Sindbis virus infection and is an important determinant of cell and tissue tropism. J. Virol 74:3366–3378.
   Google Scholar
• Sariol CA, Munoz-Jordan JL, Abel K, Rosado LC, Pantoja P, Giavedoni L, Rodriguez IV, White LJ, Martinez M, Arana T, Kraiselburd EN. (2007). Transcriptional activation of interferon-stimulated genes but not of cytokine genes after primary infection of rhesus macaques with dengue virus type 1. Clin. Vaccine Immunol 14:756–766.
   PubMedGoogle Scholar
• Sharma A, Bhattacharya B, Puri RK, Maheshwari RK. (2008). Venezuelan equine encephalitis virus infection causes modulation of inflammatory and immune response genes in mouse brain. BMC Genomics 9: 289.
   PubMed Web of Science ®Google Scholar
• Smith JA, Schmechel SC, Raghavan A, Abelson M, Reilly C, Katze MG, Kaufman RJ, Bohjanen PR, Schiff LA. (2006). Reovirus induces and benefits from an integrated cellular stress response. J. Virol 80:2019–2033.
   PubMed Web of Science ®Google Scholar
• Sui Y, Potula R, Pinson D, Adany I, Li Z, Day J, Buch E, Segebrecht J, Villinger F, Liu Z, Huang M, Narayan O, Buch S. (2003). Microarray analysis of cytokine and chemokine genes in the brains of macaques with SHIV-encephalitis. J. Med. Primatol 32:229–239.
   Google Scholar
• Tumpey TM, Szretter KJ, Van Hoeven N, Katz JM, Kochs G, Haller O, Garcia-Sastre A, Staeheli P. (2007). The Mx1 gene protects mice against the pandemic 1918 and highly lethal human H5N1 influenza viruses. J. Virol 81:10818–10821.
   PubMed Web of Science ®Google Scholar
• Venter M, Myers TG, Wilson MA, Kindt TJ, Paweska JT, Burt FJ, Leman PA, Swanepoel R. (2005). Gene expression in mice infected with West Nile virus strains of different neurovirulence. Virology 342:119–140.
   Google Scholar
• Wacher C, Muller M, Hofer MJ, Getts DR, Zabaras R, Ousman SS, Terenzi F, Sen GC, King NJ, Campbell IL. (2007). Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses. J. Virol 81: 860–871.
   PubMed Web of Science ®Google Scholar
• Wang J, Campbell IL. (2005). Innate STAT1-dependent genomic response of neurons to the antiviral cytokine alpha interferon. J. Virol 79:8295–8302.
   Google Scholar
• Warke RV, Xhaja K, Martin KJ, Fournier MF, Shaw SK, Brizuela N, de Bosch N, Lapointe D, Ennis FA, Rothman AL, Bosch I. (2003). Dengue virus induces novel changes in gene expression of human umbilical vein endothelial cells. J. Virol 77:11822–11832.
   PubMed Web of Science ®Google Scholar
• Xin H, D'Souza S, Jorgensen TN, Vaughan AT, Lengyel P, Kotzin BL, Choubey D. (2006). Increased expression of Ifi202, an IFN-activatable gene, in B6.Nba2 lupus susceptible mice inhibits p53-mediated apoptosis. J. Immunol 176:5863–5870.
   Google Scholar
• Zurney J, Kobayashi T, Holm GH, Dermody TS, Sherry B. (2009). Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9. J. Virol 83:2178–2187.
   Google Scholar