7
Views
4
CrossRef citations to date
0
Altmetric
Original Article

Prospects for therapy of HIV-associated neurologic diseases

&
Pages 89-101 | Received 26 Nov 1996, Accepted 02 Dec 1996, Published online: 10 Jul 2009

References

  • Acker M B. Relationships between test scores and everyday life functioning. Clinical Neuropsychology of Intervention, B P Uzzell, Y Gross. Martinus Nijhoff Publishing, Boston 1986; 85–117
  • Ad Hoc FDA Dementia Assessment Task Force. Antidementia Drug Assessment Symposium. Neurobiology of Aging 1991; 12: 379–382
  • Adamson D C, Wildemann B, Sasaki M, Glass J D, McArthur J C, Christov V I, Dawson T M, Dawson V L. Immunologic nitric oxide synthase: Elevation in severe AIDS dementia and induction by HIV‐1 coat protein, gp41. Science 1996; 274: 1917–1921
  • Albert S M, Marder K, Dooneief G, Bell K, Sano M, Todak G, Stern Y. Neuropsychologic impairment in early HIV infection. A risk factor for work disability. Arch Neurol 1995a; 52: 525–530
  • Albert S M, Todak G, Elkin E, Marder K, Dooneief G, Stern Y. Time allocation and disability in HIV infection: A correlational study. J Occup Sci 1995b; 1: 21–30
  • Bacellar H, Munoz A, Miller E N, Cohen B A, Besley D, Seines O A, Becker J T, McArthur J C. Temporal trends in the incidence of HIV‐1 related neurologic diseases: Multicenter AIDS Cohort Study, 1985–1992. Neurology 1994; 44: 1892–1900
  • Barker P B, Lee R R, McArthur J C. AIDS dementia complex: Evaluation with proton MR spectroscopic imaging. Radiology 1995; 195: 58–64
  • Belman A L, Diamond G, Dickson D, Horoupian D, Llena J, Lantos G, Rubinstein A. Pediatric acquired immunodeficiency syndrome. Neurologic syndromes ‘published erratum appears in Am J Dis Child 1988 May; 142(5):507’. Am J Dis Child 1988; 142: 29–35
  • Benos D J, Hahn B H, Bubien J K, Ghosh S K, Mashbum N A, Chaikin M A, Shaw G M, Benveniste E N. Envelope glycoprotein gp120 of human immunodeficiency virus type 1 alters ion transport in astrocytes: Implications for AIDS dementia complex. Proc Natl Acad Sci USA 1994; 91: 494–498
  • Bouwman F H, Skolasky R, Hes D, Seines O A, Glass J D, Nance‐Sproson T E, Royal W, Dal Pan G J, McArthur J C. Rapid progression of HIV‐associated dementia: Association with CNS immune activation. 1996, (Un Pub)
  • Burger D M, Kraayeveld C L, Meenhorst P L, Mulder J W, Hoetelmans R M W, Koks C H W, Beijnen J H. Study on didanosine concentrations in cerebrospinal fluid. Pharmacy World & Science 1995; 17: 218–221
  • Butler K M, Husson R N, Balis R M, Brouwers P, Eddy J, el‐Amin D, Gress J, Hawkins M, Jarosinki P, Moss H, Poplack D, Santacroce S, Venzon D, Wiener L, Wolters P, Pizzo P A. Dideoxyinosine in children with symptomatic human immunodeficiency virus infection. N Engl J Med 1991; 324: 137–144
  • Chiesi A, Vella S, Dally L G, Pedersen C, Danner S, Johnson A M, Schwander S, Goebel F D, Glauser M, Antunes F, Lundgren J D. Epidemiology of AIDS dementia complex in Europe. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 1996; 11: 39–44
  • Cinque P, Vago L, Brytting M, Castagna A, Accordini A, Sundqvist V ‐A, Zanchetta N, D'Arminio Monforte A, Wahren B, Lazzarin A, Linde A. Cytomegalovirus infection of the central nervous system in patients with AIDS: diagnosis by DNA amplification from cerebrospinal fluid. J Infect Dis 1992; 166: 1408–1411
  • Cinque P, Vago L, Dahl H, Brytting M, Terreni M R, Fornara C, Racca S, Castagna A, Monforte A D, Wahren B, Lazzarin A, Linde A. Polymerase chain reaction on cerebrospinal fluid for diagnosis of virus‐associated opportunistic diseases of the central nervous system in HIV‐infected patients. AIDS 1996; 10: 951–958
  • Cohen B A, McArthur J C, Grohman S, Patterson B, Glass J D. Neurologic prognosis in CMV polyradiculomyelopathy in AIDS. Neurology 1993; 43: 493–499
  • Cohen R A, O'Donnell B F, Meadows M E, Moonis M, Stone W F, Drachman D A. ERP indicies and neuropsychological performance as predictors of functional outcome in dementia. Journal of Geriatric Psychiatry & Neurology 1995; 8: 217–225
  • Dana Consortium for Treatment of HIV Dementia. Anti‐oxidant treatment in HIV dementia. Neuroscience of HIV Infection March 6–9, 1996, Paris
  • Davis K L, Thai L J, Gamzu E R, Davis C S, Woolson R F, Gracon S I, Drachman D A, Schneider L S, Whitehouse P J, Hoover T M, Morris J C, Kawas C H, Knopman D S, Earl N L, Kumar V, Doody RS and The Tacrine Collaborative Study Group. A double‐blind, placebo‐controlled multicenter study of tacrine for Alzheimer's disease. N Engl J Med 1992; 327: 1253–1259
  • Dewhurst S, Gelbard H A, Fine S M. Neuropathogenesis of AIDS (review). Molecular Medicine Today 1996; 2: 16–23
  • Dieterich D T, Poles M A, Lew E A, Mendez P A, Murphy R, Addessi A, Holbrook J T, Naughton K, Friedberg D N. Concurrent use of ganciclovir and foscarnet to treat cytomegalovirus infection in AIDS patients. J Infect Dis 1993; 167: 1184–1188
  • Fein G, Biggins C A, Mackay S. Delayed latency of the event‐related brain potential P3A component in HIV disease. Progressive effects with increasing cognitive impairment. Arch Neurol 1995; 52: 1109–1118
  • Fillet A M, Katlama C, Visse B, Camilleri S, Rogeaux O, Huraux J M. Human CMV infection of the CNS: concordance between PCR detection in CSF and pathological examination. AIDS 1993; 7: 1016–1017
  • Gallant J E, Moore R D, Richman D D, Keruly J, Chaisson R E, Zidovudine Epidemiology Study Group. Incidence and natural history of cytomegalovirus disease in patients with advanced human immunodeficiency virus disease treated with zidovudine. J Infect Dis 1992; 166: 1223–1227
  • Gelbard H A, Dzenko K A, DiLoreto D, del Cerro C, del Cerro M, Epstein L G. Neurotoxic effects of tumor necrosis factor alpha in primary human neuronal cultures are mediated by activation of the glutamate AMPA receptor subtype: Implications for AIDS neuropathogenesis. Dev Neurosci 1993; 15: 417–422
  • Gelbard H A, Nottet H S L M, Swindells S, Jett M, Dzenko K A, Genis P, White R, Wang L, Choi Y B, Zhang D X, Lipton S A, Tourtellotte W W, Epstein L G, Gendelman H E. Platelet activating factor. A candidate human immunodeficiency virus type 1‐induced neurotoxin. J Virol 1994; 68: 4628–4635
  • Glass J D, Fedor H, Wesselingh S L, McArthur J C. Immunocytochemical quantitation of HIV in the brain: Correlations with HIV‐associated dementia. Ann Neurol 1995; 38: 755–762
  • Gozlan J, Salord J M, Roullet E, Baudrimont M, Caburet F, Meyohas M C, Duvivier C, Jacomet C, Petit J C. Rapid detection of cytomegalovirus DNA in cerebrospinal fluid of AIDS patients with neurologic disorders. J Infect Dis 1992; 166: 1416–1421
  • Gozlan J, El Amrani M, Baudrimont M, Costagliola D, Salord J M, Duvivier C, Picard O, Meyohas M, Jacomet C, Schneider‐Fauveau V, Petit J ‐C, Roullet E. A prospective evaluation of clinical criteria and polymerase chain reaction assay of cerebrospinal fluid for the diagnosis of cytomegalovirus‐related neurological diseases during AIDS. AIDS 1995; 9: 253–260
  • Graham N M H, Hoover D R, Park L P, Stein D S, Phair J P, Mellors J W, Detels R, Saah A J, Taylor E, Margolick J B, Markham R, McArthur J, Farzadegan H, Armenian H, Chmeil J S, Cohen B, Wesch J, Wolinsky S, Visscher B R, Fahey J L, Giorgi J V, Dudley J, Lee M, Nishanian P, Rinaldo C R. Survival in HIV‐infected patients who have received zidovudine. Comparison of combination therapy with sequential monotherapy and continued zidovudine monotherapy. Ann Intern Med 1996; 124: 1031–1038
  • Griffin D E, Wesselingh S L, McArthur J C. Elevated central nervous system prostaglandins in HIV‐associated dementia. Ann Neurol 1994; 35: 592–597
  • Heaton R K, Chelune G J, Lehman R A. Using neuropsychological and personality tests to assess the likelihood of patient employment. J Nerv Ment Dis 1978; 166: 408–416
  • Heaton R K, Velin R A, McCutchan J A, Gulevich S J, Atkinson J H, Wallace M R, Godfrey H P D, Kirson D A, Grant I, The HNRC Group. Neuropsychological impairment in human immunodeficiency virus‐infection: Implications for employment. Psychosomatic Med 1994; 56: 8–17
  • Hill R D, Backman L, Fratiglioni L. Determinants of functional abilities in dementia. J Am Geriatrics Soc 1995; 43: 1092–1097
  • Huang S, Skolasky R, Dal Pan G J, Royal W, McArthur J C. Survival prolongation and sympton palliation in HIV seropositive patients with PML treated with alpha interferon. 1996, (Un Pub)
  • Janssen R S, Nwanyanwu O C, Selik R M, Stehr‐Green J K. Epidemiology of human immunodeficiency virus encephalopathy in the United States. Neurology 1992; 42: 1472–1476
  • Kerr D A, Chang C F, Gordon J, Bjornsti M A, Khalili K. Inhibition of human neurotropic virus (JCV) DNA replication in glial cells by camptothecin. Virology 1993; 196: 612–618
  • Koka P, Zack J A, Kitchen S, Peacock W, Fried I, Tran Y, Yashar S S, Merrill J E. Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor alpha and nitric oxide in glial cultures derived from fetal, neonatal, and adult human brain. J Exp Med 1995; 182: 941–951
  • Lipton S A, Gendelman H E. Dementia associated with the acquired immunodeficiency syndrome. N Engl J Med 1995; 332: 934–940
  • Magnuson D S K, Knudsen B E, Geiger J D, Brownstone R M, Nath A. Human immunodeficiency virus type 1 Tat activates non‐N‐methyl‐D‐aspartate excitatory amino acid receptors and causes neurotoxicity. Ann Neurol 1995; 37: 373–380
  • Maj M, Satz P, Janssen R, Zaudig M, Starace F, D'Elia L, Sughondhabirom B, Mussa M, Naber D, Ndetei D, Schulte G, Sartorius N. WHO Neuropsychiatry AIDS Study, Cross‐sectional Phase II. Neuropsychological and neurological findings. Arch Gen Psychiatry 1994; 51: 51–61
  • Manischewitz J F, Quinnan G V, Lane H C, Wittek A E. Synergistic effect of ganciclovir and foscarnet on cytomegalovirus replication in vitro. Antimicrob Agents Chemother 1990; 34: 373–375
  • McArthur J C, Seines O A, Dal Gan G J, Yost B, Oette D, Gelpke L, Clifford D, Price R W, Wesselingh S, Griffin D E. Phase I/II trial of pentoxifylline in HIV‐associated dementia and myelopathy. Neuroscience of HIV Infection: Basic and Clinical Frontiers Vancouver BC. Aug 2–5, 1994
  • McArthur J C, Grant I. HIV neurocognitive disorders. Neurological and Neuropsychiatric Manifestations of HIV‐1 Infection. 1996, (In Press)
  • McConnell J R, Swindells S, Ong C S, Gmeiner W H, Chu W K, Brown D K, Gendelman H E. Prospective utility of cerebral proton magnetic resonance spectroscopy in monitoring HIV infection and its associated neurological impairment. AIDS Res Hum Retroviruses 1994; 10: 977–982
  • McKinney R E, Jr, Maha M A, Connor E M, Feinberg J, Scott G B, Wulfsohn M, McIntosh K, Borkowsky W, Modlin J F, Weintrub P, O'Donnell K, Gelber R D, Knowlton Rogers G, Nusinoff Lehrman S, Wilfert C M, Protocol 043 Study Group. A multicenter trial of oral zidovudine in children with advanced human immunodeficiency virus disease. N Engl J Med 1991; 324: 1018–1025
  • Moore R D, Chaisson R E. Natural history of opportunistic disease in an HIV‐infected urban clinical cohort. Ann Intern Med 1996; 124: 633
  • Navia B A, Dafni U, Simpson D, Slasor P, McArthur J, Zaborski L, Lipton S A. A Phase I/II trial of nimodipine for the treatment of neurological manifestations associated with HIV infection, including AIDS dementia complex and peripheral neuropathy. 1996, (Un Pub)
  • Nordic Medical Research Councils HIV Therapy Group. Double blind dose‐response study of zidovudine in AIDS and advanced HIV infection. Br Med J 1992; 304: 13–17
  • Persidsky Y, Limoges J, McComb R, Bock P, Baldwin T, Tyor W, Patil A, Nottet H S L., Epstein L, Gelbard H, Flanagan E, Reinhard J, Pirruccello S J, Howard E, Gendelman H E. Human immunodeficiency virus encephalitis in SCID mice. Am J Pathol 1996; 149: 1027–1053
  • Philippon V, Vellutini C, Gambarelli D, Harkiss G, Arbuthnott G, Metzger D, Roubin R, Filippi P. The basic domain of the lentiviral Tat protein is responsible for damages in mouse brain: Involvement of cytokines. Virology 1994; 205: 519–529
  • Pizzo P A, Eddy J, Falloon J, Balis F M, Murphy R F, Moss H, Wolters P, Brouwers P, Jarosinski P, Rubin M. Effect of continuous intravenous infusion of zidovudine (AZT) in children with symptomatic HIV infection. N Engl J Med 1988; 319: 889–896
  • Portegies P, de Gans J, Lange J M, Derix M M, Speelman H, Bakker M, Danner S A, Goudsmit J. Declining incidence of AIDS dementia complex after introduction of zidovudine treatment ‘published erratum appears in BMJ 1989 Nov 4;299(6708):1141’. Br Med J 1989; 299: 819–821
  • Rao S M, Leo G J, Ellington L, Nauertz T, Bernardin L, Unverzagt F. Cognitive dysfunction in multiple sclerosis. II. Impact on employment and social functioning. Neurology 1991; 41: 692–696
  • Rothlind J C, Bylsma F W, Peyser C, Folstein S E, Brandt J. Cognitive and motor correlates of everyday functioning in early Huntington's disease. J Nerv Ment Dis 1993; 181: 194–199
  • Sardar A M, Bell J E, Reynolds G P. Increased concentrations of the neurotoxin 3‐hydroxykynurenine in the frontal cortex of HIV‐1 ‐positive patients. J Neurochem 1995; 64: 932–935
  • Sidtis J J, Gatsonis C, Price R W, Singer E J, Collier A C, Richman D D, Hirsch M S, Schaerf F W, Fischl M A, Kieburtz K, Simpson D, Koch M A, Feinberg J, Dafni R, AIDS Clinical Trials Group. Zidovudine treatment of the AIDS dementia complex: results of a placebo‐controlled trial. Ann Neurol 1993; 33: 343–349
  • Sidtis J J. Evaluation of the AIDS dementia complex in adults. HIV, AIDS and the Brain, R W Price, S W Perry. Raven Press, New York 1994; 273–287
  • Talley A K, Dewhurst S, Perry S, Dollard S C, Gummuluru S, Fine S M, New D, Epstein L G, Gendelman H E, Gelbard H A. Tumor necrosis factor alpha induces apoptosis in human neuronal cells: Protection by the antioxidant N‐acetylcysteine and the genes bcl‐2 and crm A. Mol Cell Biol 1995; 15: 2359–2366
  • The Dana Consortium on Therapy for HIV Dementia and Related Cognitive Disorders. Clinical confirmation of the American Academy of Neurology algorithm for HIV‐1 associated cognitive/motor disorder. Neurology 1996; 47: 1247–1253
  • Toggas S M, Masliah E, Rockenstein E M, Rail G F, Abraham C R, Mucke L. Central nervous system damage produced by expression of the HIV‐1 coat protein gp120 in transgenic mice. Nature 1994; 367: 188–193
  • Tozzi V, Narciso P, Galgani S, Sette P, Balestra P, Gerace C, Pau F M, Pigorini F, Volpini V, Camporiondo M P. Effects of zidovudine in 30 patients with mild to end‐stage AIDS dementia complex. AIDS 1993; 7: 683–692
  • Tross S, Price R W, Navia B, Thaler H T, Gold J, Sidtis J J. Neuropsychololgical characterization of the AIDS dementia complex: a preliminary report. AIDS 1988; 2: 81–88
  • Van Gorp W G, Hinkin C, Satz P, Miller E N, Weisman J, Holston S, Drebing C, Marcotte T D, Dixon W. Subtypes of HIV‐related neuropsychological functioning: a cluster analysis approach. Neuropsychology 1993; 7: 62–72
  • Volterra A, Trotti D, Racagni G. Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms. Mol Phar 1994; 46: 986–992
  • Weinberg D V, Murphy R, Naughton K. Combined daily therapy with intravenous ganciclovir and foscarnet for patients with recurrent cytomegalovirus retinitis. Am J Ophthalmol 1994; 117: 776–782
  • Weinshenker B G, Issa M, Baskerville J. Metaanalysis of the placebo‐treated groups in clinical trials of progressive MS. Neurology 1996; 46: 1613–1619
  • Wesselingh S L, Power C, Glass J, Tyor W R, McArthur J C, Farber J M, Griffin J W, Griffin D E. Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia. Ann Neurol 1993; 33: 576–582
  • Wolf D G, Spector S A. Diagnosis of human cytomegalovirus central nervous system disease in AIDS patients by DNA amplification from cerebrospinal fluid. J Infect Dis 1992; 166: 1412–1415
  • Yeung M C, Pulliam L, Lau A S. The HIV envelope protein gp120 is toxic to human brain‐cell cultures through the induction of interleukin‐6 and tumor necrosis factor‐a. AIDS 1995; 9: 137–143

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.