BDNF and ARTEMIN are increased in drug-naïve non-depressed GAD patients: Preliminary data

References

• Alleva E, Petruzzi S, Cirulli F, Aloe L. 1996a. NGF regulatory role in stress and coping of rodents and humans. Pharmacol Biochem Behav 54:65–72.
   PubMed Web of Science ®Google Scholar
• Alleva E, Aloe L, Cirulli F, Della Seta D, Tirassa P. 1996b. Serum NGF levels increase during lactation and following maternal aggression in mice. Physiol Behav 59:461–466.
   PubMed Web of Science ®Google Scholar
• Aloe L, Bracci-Laudiero L, Alleva L, Lambiase E, Micera A, Tirassa P. 1994. Emotional stress induced by parachute jumping enhances blood nerve growth factor levels and the distribution of nerve growth factor receptors in lymphocytes. Proc Natl Acad Sci USA 91:10440–10444.
   PubMed Web of Science ®Google Scholar
• American Psychiatric Association (APA). 2000. Diagnostic and statistical manual of mental disorder IV Text Revised. American Psychiatric Publishing.
   Google Scholar
• American Psychiatric Association (APA). 2013. Diagnostic and statistical manual of mental disorder V. American Psychiatric Publishing.
   Google Scholar
• Arranz L, Guayerbas N, De la Fuente M. 2007. Impairment of several immune functions in anxious women. J Psychosom Res 62:1–8.
   PubMed Web of Science ®Google Scholar
• Baldwin DS, Allgulander C, Bandelow B, Ferre F, Pallanti S. 2012. An international survey of reported prescribing practice in the treatment of patients with generalized anxiety disorder. World. J Biol Psychiatry 13:510–516.
   PubMed Web of Science ®Google Scholar
• Ball S, Marangell L, Lipsius S, Russel J. 2013. Brain-derived neurotrophic factor in generalized anxiety disorder: results from a duloxetine clinical trial. Prog Neuropsychopharmacol Biol Psychiatry 43C:217–221.
   Google Scholar
• Barres BA. 2003. What is a glial cell?. Glia 43:4–5.
   PubMed Web of Science ®Google Scholar
• Berger W, Mehra A, Lenoci M, Metzler TJ, Otte C, Tarasovsky G, et al. 2010. Serum brain-derived neurotrophic factor predicts responses to escitalopram in chronic posttraumatic stress disorder. Prog Neuropsychopharmacol Biol Psychiatry 34: 1279–1284.
   PubMed Web of Science ®Google Scholar
• Böyum A. 1968. Separation of leukocytes from blood and bone marrow. Introduction. Scand J Clin Lab Invest Suppl 97:7.
   PubMedGoogle Scholar
• Bus BA, Molendijk ML, Penninx BJ, Buitelaar JK, Kenis G, Prickaerts J, et al. 2011. Determinants of serum brain-derived neurotrophic factor. Psychoneuroendocrinology 36:228–229.
   PubMed Web of Science ®Google Scholar
• Chaldakov GN, Fiore M, Tonchev AB, Dimitrov D, Pancheva R, Rancic G, et al. 2007. Homo obesus: a metabotrophin-deficient species. Pharmacology and Nutrition Insight. Curr Pharm Des 13:2176–2179.
   PubMed Web of Science ®Google Scholar
• Dell’Osso L, Carmassi C, Del Debbio A, Dell’Osso MC, Bianchi C, da Posso E, et al. 2009. Brain-derived neurotrophic factor plasma levels in patients suffering from post-traumatic stress disorder. Prog Neuropsychopharmacol Biol Psychiatry 33:899–902.
   PubMed Web of Science ®Google Scholar
• Di Cesare Mannelli L, Vivoli E, Salvicchi A, Schiavone N, Koverech A, Messano M, et al. 2011. Antidepressant-like effect of artemin in mice: a mechanism for acetyl-L-carnitine activity on depression. Psychopharmacology 218:347–356.
   PubMed Web of Science ®Google Scholar
• First MB, Spitzer RL, Gibbon M, Gibbon W, Janet BW. 2002a. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition With Psychotic Screen (SCID-I/P W/PSY SCREEN) New York: Biometrics Research, New York State Psychiatric Institute.
   Google Scholar
• First MB, Spitzer RL, Gibbon M, Gibbon W, Janet BW, et al. 2002b. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Non-patient Edition. (SCID-I/NP) New York: Biometrics Research, New York State Psychiatric Institute.
   Google Scholar
• Gill J, Vythilingam M, Page G. 2008. Low cortisol, high DHEA, and high levels of TNF-α and IL-6 in women with PTSD. J Traumatic Stress 21:530–539.
   PubMed Web of Science ®Google Scholar
• Gonul AS, Kitis O, Eker MC, Eker OD, Ozan E, Coburn K. 2011. Association of the brain-derived neurotrophic factor Val66Met polymorphism with hippocampus volumes in drug-free depressed patients. World J Biol Psychiatry 12:110–118.
   PubMed Web of Science ®Google Scholar
• Hadjiconstantinou M, McGuire L, Duchemin AM, Laskowski B, Klecolt-Glaser J, Glaser R. 2001. Changes in plasma nerve growth factor levels in older adults associated with chronic stress. J Neuroimmunol 116:102–106.
   Google Scholar
• Hamilton M. 1960. A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56–62.
   PubMed Web of Science ®Google Scholar
• Hoge EA, Brandstetter K, Moshier S, Pollack MH, Wong KK, Simon NM. 2009. Broad spectrum of cytokine abnormalities in panic disorder and ptsd. Depress Anxiety 26:447–455.
   PubMed Web of Science ®Google Scholar
• Johansson M, Jönsson M, Norrgård O, Forsgren S. 2008. New aspects concerning ulcerative colitis and colonic carcinoma: analysis of levels of neuropeptides, neurotrophins, and TNFalpha/TNF receptor in plasma and mucosa in parallel with histological evaluation of the intestine. Inflamm Bowel Dis. 14:1331–1340.
   PubMed Web of Science ®Google Scholar
• Kang J, Perry JK, Pandey V, Fielder GC, Mei B, Qian PX, et al. 2009. Artemin is oncogenic for human mammary carcinoma cells. Oncogene 28:2034–2045.
   PubMedGoogle Scholar
• Lee HY, Yong KK. 2008. Plasma Brain-derived neurotrophic factor as a peripheral marker of the action of antidepressants. Neuropsychobiology 57:194–199.
   Google Scholar
• Liu HT, Tyagi P, Chancellor MB, Kuo HC. 2009. Urinary nerve growth factor level is increased in patients with interstitial cystitis/bladder pain syndrome and decreased in responders to treatment. BJU Int 104:1476–1481.
   PubMed Web of Science ®Google Scholar
• Moffitt TE, Harrington H, Caspi A, Kim-Cohen J, Goldberg D, Gregory AM, et al. 2007. Cumulative and sequential comorbidity in a birth cohort followed prospectively to age 32 years. Arch Gen Psychiatry 64:651–660.
   PubMed Web of Science ®Google Scholar
• Molendijk ML, Bus BA, Spinhove P, Penninx BW, Prickaerts J, Oude V, et al. 2012. Gender specific associations of serum levels of brain-derived neurotrophic factor in anxiety. World J Biol Psychiatry 13:535–43.
   PubMed Web of Science ®Google Scholar
• Otsuki K, Uchida S, Watanuki T, Wakabayashi Y, Fujimoto M, Matsubara T, et al. 2008. Altered expression of neurotrophic factors in patients with major depression. J Psychiatr Res 42:1145–1153.
   PubMed Web of Science ®Google Scholar
• Ruan L, Lau BW, Wang J, Huang L, Zhuge Q, Wang B, et al. 2014. Neurogenesis in neurological and psychiatric diseases and brain injury: from bench to bedside. Prog Neurobiol 115:116–137.
   PubMed Web of Science ®Google Scholar
• Schwarz JM, Bilbo SD. 2012. Sex, glia and development: interactions in health and disease. Horm Behav 62:243–253.
   PubMed Web of Science ®Google Scholar
• Sen S, Duman R, Sanacora G. 2008. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta – analyses and implications. Biol Psychiatry 64:527–532.
   PubMed Web of Science ®Google Scholar
• Shieh KR, Yi CH, Liu TT, Tseng HL, Ho HC, Hsieh HT, Chen CL. 2010. Evidence for neurotrophic factors associating with TRPV1 gene expression in the inflamed human esophagus. Neurogastroenterol Motil 22:971–977.
   Google Scholar
• Spitzer RL, Kroenke K, Williams JB, Lowe B. 2006. A brief measure for assessing generalized anxiety disorder. Arch Intern Med 166:1092–1097.
   PubMed Web of Science ®Google Scholar
• Takebayashi M, Hisaoka K, Nishida A, Tsuchioka M, Miyoshi I, Kozuru T, et al. 2006. Decreased levels of whole blood glial cell line-derived neurotrophic factor (GDNF) in remitted patients with mood disorders. Int J Neuropychopharmacol 9:607–612.
   PubMed Web of Science ®Google Scholar
• Takkouche B, Regueira C, Gestal-Otero JJ. 2001. A cohort study of stress and the common cold. Epidemiology 12:345–349.
   PubMed Web of Science ®Google Scholar
• Vieira MM, Ferreira TB, Pacheco PA, Barros PO, Almeida CR, Araújo-Lima CF, et al. 2010. Enhanced Th17 phenotype in individuals with generalized anxiety disorder. J Neuroimm 229:212–218.
   PubMed Web of Science ®Google Scholar
• Von Boyen GB., Steinkamp M, Geerling I, Reinshagen M, Schäfer KH, Adler G, et al. 2006. Proinflammatory cytokines induce neurotrophic factor expression in enteric glia: a key to the regulation of epithelial apoptosis in Crohn's disease. Inflamm Bowel Dis 12:346–354.
   Google Scholar
• Zhang X, Zhang Z, Xie C, Xi G, Zhou H, Zhang Y, et al. 2008. Effect of treatment on serum glial cell line-derived neurotrophic factor in depressed patients. Prog Neuropsychopharmacol Biol Psychiatry 32:886–890.
   PubMed Web of Science ®Google Scholar