Histoplasma capsulatum and Caenorhabditis elegans: a simple nematode model for an innate immune response to fungal infection

References

• Woods JP, Heinecke EL, Luecke JW, . Pathogenesis of Histoplasma capsulatum. Semin Respir Infect. 2001; 16:91–101.
   PubMedGoogle Scholar
• Kauffman CA. Endemic mycoses: blastomycosis, histoplasmosis, and sporotrichosis. Inf Dis Clin North Amer. 2006; 20:645–62.vii.
   PubMed Web of Science ®Google Scholar
• Eissenberg LG, Goldman WE. Histoplasma variation and adaptive strategies for parasitism: new perspectives on histoplasmosis. Clin Microbiol Rev 1991; 4:411–421.
   PubMed Web of Science ®Google Scholar
• Ampel NM. Emerging disease issues and fungal pathogens associated with HIV infection. Emerg Infect Dis 1996; 2:109–116.
   PubMed Web of Science ®Google Scholar
• Kauffman CA. Diagnosis of histoplasmosis in immunosuppressed patients. Curr Opin Inf Dis 2008; 21:421–425.
   PubMedGoogle Scholar
• Deepe GS Jr. Immune response to early and late Histoplasma capsulatum infections. Curr Opin Microbiol 2000; 3:359–362.
   Google Scholar
• Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392:245–252.
   PubMed Web of Science ®Google Scholar
• Huffnagle GB, Deepe GS. Innate and adaptive determinants of host susceptibility to medically important fungi. Curr Opin Microbiol 2003; 6:344–350.
   PubMed Web of Science ®Google Scholar
• Cole GT, Xue JM, Okeke CN, . A vaccine against coccidioidomycosis is justified and attainable. Med Mycol 2004; 42:189–216.
   PubMed Web of Science ®Google Scholar
• Nosanchuk JD. Protective antibodies and endemic dimorphic fungi. Curr Mol Med 2005; 5:435–442.
   PubMed Web of Science ®Google Scholar
• Cutler JE, Deepe GS Jr, Klein BS. Advances in combating fungal diseases: vaccines on the threshold. Nat Rev Microbiol 2007; 5:13–28.
   PubMed Web of Science ®Google Scholar
• Chamilos G, Lionakis MS, Lewis RE, Kontoyiannis DP. Role of mini-host models in the study of medically important fungi. Lancet-Inf Dis 2007; 7:42–55.
   PubMed Web of Science ®Google Scholar
• Steenbergen JN, Nosanchuk JD, Malliaris SD, Casadevall A. Interaction of Blastomyces dermatitidis, Sporothrix schenckii, and Histoplasma capsulatum with Acanthamoeba castellanii. Inf Immun 2004; 72:3478–3488.
   PubMedGoogle Scholar
• Alegado RA, Campbell MC, Chen WC, Slutz SS, Tan MW. Characterization of mediators of microbial virulence and innate immunity using the Caenorhabditis elegans host-pathogen model. Cell Microbiol 2003; 5:435–444.
   PubMed Web of Science ®Google Scholar
• Kauffman CA. Fungal infections. Clin Ger Med 1992; 8:777–791.
   PubMedGoogle Scholar
• Mylonakis E, Ausubel FM, Perfect JR, Heitman J, Calderwood SB. Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. Proc Nat Acad Sci USA 2002; 99:15675–15680.
   PubMed Web of Science ®Google Scholar
• Kasuga T, White TJ, Koenig G, . Phylogeography of the fungal pathogen Histoplasma capsulatum. Mol Ecol 2003; 12:3383–3401.
   PubMed Web of Science ®Google Scholar
• Kugler S, Young B, Miller VL, Goldman WE. Monitoring phase-specific gene expression in Histoplasma capsulatum with telomeric GFP fusion plasmids. Cell Microbiol 2000; 2:537–547.
   PubMedGoogle Scholar
• Worsham PL, Goldman WE. Quantitative plating of Histoplasma capsulatum without addition of conditioned medium or siderophores. J Med Vet Mycol 1988; 26:137–143.
   PubMedGoogle Scholar
• Woods JP, Retallack DM, Heinecke EL, Goldman WE. Rare homologous gene targeting in Histoplasma capsulatum: disruption of the URA5Hc gene by allelic replacement. J Bacteriol 1998; 180:5135–5143.
   PubMedGoogle Scholar
• Ayyadevara S, Dandapat A, Singh SP, . Lifespan extension in hypomorphic daf-2 mutants of Caenorhabditis elegans is partially mediated by glutathione transferase CeGSTP2-2. Aging cell 2005; 4:299–307.
   PubMed Web of Science ®Google Scholar
• Breger J, Fuchs BB, Aperis G, . Antifungal chemical compounds identified using a C. elegans pathogenicity assay. PLoS Path 2007; 3:e18–
   PubMed Web of Science ®Google Scholar
• Ayyadevara S, Dandapat A, Singh SP, . Life span and stress resistance of Caenorhabditis elegans are differentially affected by glutathione transferases metabolizing 4-hydroxynon-2-enal. Mech Aging Develop 2007; 128:196–205.
   PubMed Web of Science ®Google Scholar
• Janeway CA, Jr. How the immune system protects the host from infection. Microbes Inf/ Institut Pasteur 2001; 3:1167–1171.
   PubMed Web of Science ®Google Scholar
• Janeway CA, Jr. A trip through my life with an immunological theme. Ann Rev Immunol 2002; 20:1–28.
   PubMed Web of Science ®Google Scholar
• Fuchs BB, Mylonakis E. Using non-mammalian hosts to study fungal virulence and host defense. Curr Opin Mocrobiol 2006; 9:346–351.
   PubMed Web of Science ®Google Scholar