40
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Expression of activation and cytotoxic molecules by peripheral blood lymphocytes of patients with paracoccidioidomycosis

, , , &
Pages 843-852 | Received 23 Jul 2009, Accepted 24 Dec 2009, Published online: 18 Feb 2010

References

  • Franco M, Peracoli MT, Soares A, . Host-parasite relationship in paracoccidioidomycosis. Curr Top Med Mycol 1993;5:115–149.
  • Franco M, Montenegro MR, Mendes RP, . Paracoccidioidomycosis: a recently proposed classification of its clinical forms. Rev Soc Bras Med Trap 1987;20:129–132.
  • Franco M. Host-parasite relationships in paracoccidioidomycosis. J Med Vet Mycol 1987;25:5–18.
  • Cano LE, Singer-Vermes LM, Costa TA, . Depletion of CD8(+) T cells in vivo impairs host defense of mice resistant and susceptible to pulmonary paracoccidioidomycosis. Infect Immun 2000;68:352–359.
  • Fornazim MC, Balthazar A, Quagliato R Jr., . Evaluation of bronchoalveolar cells in pulmonary paracoccidioidomycosis. Eur Respir J 2003;22:895–899.
  • Pagliari C, Pereira NV, Kanashiro L, . Characterization of cytotoxic immune response in skin and mucosal lesions of paracoccidioidomycosis. J Cutan Pathol 2009.
  • Vankayalapati R, Klucar P, Wizel B, . NK cells regulate CD8+ T cell effector function in response to an intracellular pathogen. J Immunol 2004;172:130–137.
  • Okada S, Li Q, Whitin JC, Clayberger C, Krensky AM. Intracellular mediators of granulysin-induced cell death. J Immunol 2003;171:2556–2562.
  • Canaday DH, Wilkinson RJ, Li Q, . CD4(+) and CD8(+) T cells kill intracellular Mycobacterium tuberculosis by a perforin and Fas/ Fas ligand-independent mechanism. J Immunol 2001;167:2734–2742.
  • Krensky AM, Clayberger C. Granulysin: a novel host defense molecule. Am J Transplant 2005;5:1789–1792.
  • Ma LL, Spurrell JC, Wang JF, . CD8 T cell-mediated killing of Cryptococcus neoformans requires granulysin and is dependent on CD4 T cells and IL-15. J Immunol 2002;169:5787–5795.
  • Zheng CF, Ma LL, Jones GJ, . Cytotoxic CD4+ T cells use granulysin to kill Cryptococcus neoformans, and activation of this pathway is defective in HIV patients. Blood 2007;109:2049–2057.
  • Wargnier A, Sasportes M, Lagrange PH. [Granulysin: antimicrobial molecule of innate and acquired immunity in human tuberculosis]. Pathol Biol (Paris) 2005;53:516–521.
  • Ogawa K, Takamori Y, Suzuki K, . Granulysin in human serum as a marker of cell-mediated immunity. Eur J Immunol 2003;33:1925–1933.
  • Tran P, Ahmad R, Xu J, Ahmad A, Menezes J. Host's innate immune response to fungal and bacterial agents in vitro: up-regulation of interleukin-15 gene expression resulting in enhanced natural killer cell activity. Immunology 2003;109:263–270.
  • Berard M, Brandt K, Bulfone-Paus S, Tough DF. IL-15 promotes the survival of naive and memory phenotype CD8+ T cells. J Immunol 2003;170:5018–5026.
  • Kennedy MK, Glaccum M, Brown SN, . Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 2000;191:771–780.
  • Judge AD, Zhang X, Fujii H, Surh CD, Sprent J. Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells. J Exp Med 2002;196:935–946.
  • Lodolce JP, Boone DL, Chai S, . IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998;9:669–676.
  • Saito K, Yajima T, Kumabe S, . Impaired protection against Myco-bacterium bovis bacillus Calmette-Guerin infection in IL-15-deficient mice. J Immunol 2006;176:2496–2504.
  • Mody CH, Spurrell JC, Wood CJ. Interleukin-15 induces antimicrobial activity after release by Cryptococcus neoformans-stimulated monocytes. J Infect Dis 1998;178:803–814.
  • Kim HS, Choi EH, Khan J, . Expression of genes encoding innate host defense molecules in normal human monocytes in response to Candida albicans. Infect Immun 2005;73:3714–3724.
  • Oliveira SJ, Mamoni RL, Musatti CC, Papaiordanou PM, Blotta MH. Cytokines and lymphocyte proliferation in juvenile and adult forms of paracoccidioidomycosis: comparison with infected and non-infected controls. Microbes Infect 2002;4:139–144.
  • Saraiva EC, Altemani A, Franco MF, Unterkircher CS. Camargo ZP Paracoccidioides brasiliensis-gp43 used as paracoccidioidin. J Med Vet Mycol 1996;34:155–161.
  • Cano LE, Singer-Vermes LM, Vaz CA, Russo M, Calich VL. Pulmonary paracoccidioidomycosis in resistant and susceptible mice: relationship among progression of infection, bronchoalveolar cell activation, cellular immune response, and specific isotype patterns. Infect Immun 1995;63:1777–1783.
  • Singer-Vermes LM, Burger E, Franco MF, . Evaluation of the pathogenicity and immunogenicity of seven Paracoccidioides brasiliensis isolates in susceptible inbred mice. J Med Vet Mycol 1989;27:71–82.
  • Mamoni RL B-SL, Blotta MHSL. The role of CD8+ cells in human paracoccidioidomycosis. Biomedica 2008;28:68.
  • Fehniger TA, Caligiuri MA. Interleukin 15: biology and relevance to human disease. Blood 2001;97:14–32.
  • Liu K, Catalfamo M, Li Y, Henkart PA, Weng NP. IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells. Proc Natl Acad Sci USA 2002;99:6192–6197.
  • Rausch A, Hessmann M, Holscher A, . Interleukin-15 mediates protection against experimental tuberculosis: a role for NKG2D-dependent effector mechanisms of CD8+ T cells. Eur J Immunol 2006;36:1156–1167.
  • Serbina NV, Liu CC, Scanga CA, Flynn JL. CD8+ CTL from lungs of Mycobacterium tuberculosis-infected mice express perforin in vivo and lyse infected macrophages. J Immunol 2000;165:353–363.
  • Vazquez N, Walsh TJ, Friedman D, Chanock SJ, Lyman CA. Interleukin-15 augments superoxide production and microbicidal activity of human monocytes against Candida albicans. Infect Immun 1998;66:145–150.
  • Tavian EG, Dias-Melicio LA, Acorci MJ, . Interleukin-15 increases Paracoccidioides brasiliensis killing by human neutrophils. Cytokine 2008;41:48–53.
  • Chiarella AP, Arruda C, Pina A, . The relative importance of CD4+ and CD8+T cells in immunity to pulmonary paracoccidioidomycosis. Microbes Infect 2007;9:1078–1088.
  • Hahn S, Stalder T, Wernli M, . Down-modulation of CD4+ T helper type 2 and type 0 cells by T helper type 1 cells via Fas/ Fas-ligand interaction. Eur J Immunol 1995;25:2679–2685.
  • Hahn S, Gehri R, Erb P. Mechanism and biological significance of CD4-mediated cytotoxicity. Immunol Rev 1995;146:57–79.
  • Faber LM, van Luxemburg-Heijs SA, Veenhof WF, Willemze R, Falkenburg JH. Generation of CD4+ cytotoxic T-lymphocyte clones from a patient with severe graft-versus-host disease after allogeneic bone marrow transplantation: implications for graft-versus-leukemia reactivity. Blood 1995;86:2821–2828.
  • Vergelli M, Hemmer B, Muraro PA, . Human autoreactive CD4+ T cell clones use perforin- or Fas/Fas ligand-mediated pathways for target cell lysis. J Immunol 1997;158:2756–2761.
  • Williams NS, Engelhard VH. Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism. J Immunol 1996;156:153–159.
  • Winn RM, Gil-Lamaignere C, Roilides E, . Selective effects of interleukin (IL)-15 on antifungal activity and IL-8 release by polymorphonuclear leukocytes in response to hyphae of Aspergillus species. J Infect Dis 2003;188:585–590.
  • Winn RM, Gil-Lamaignere C, Roilides E, . Effects of interleukin-15 on antifungal responses of human polymorphonuclear leukocytes against Fusarium spp. and Scedosporium spp. Cytokine 2005;31:1–8.
  • Bergamaschi C, Rosati M, Jalah R, . Intracellular interaction of IL-15 with its receptor alpha during production leads to mutual stabilization and increased bioactivity. J Biol Chem 2008; 283: 4189–4199
  • Sato N, Patel HJ, Waldmann TA, . The IL-15/IL-15 Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells. Proc Natl Acad Sci USA 2007;104:588–593.
  • Ochoa MT, Stenger S, Sieling PA, . T-cell release of granulysin contributes to host defense in leprosy. Nat Med 2001;7:174–179.
  • Sahiratmadja E, Alisjahbana B, Buccheri S, . Plasma granulysin levels and cellular interferon-gamma production correlate with curative host responses in tuberculosis, while plasma interferon-gamma levels correlate with tuberculosis disease activity in adults. Tuberculosis (Edinb) 2007;87:312–321.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.