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Original Article

Testosterone treatment of HSDD in naturally menopausal women: the ADORE study

, , , , , , , , , & show all
Pages 121-131 | Received 15 Jan 2010, Accepted 03 Feb 2010, Published online: 19 Feb 2010

References

  • Shifren JL, Braunstein GD, Simon JA, et al Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. N Engl J Med 2000;343:682–8
  • Braunstein GD, Sundwall DA, Katz M, et al Safety and efficacy of a testosterone patch for treatment of hypoactive sexual desire disorder in surgically menopausal women: a randomized placebo controlled trial. Arch Intern Med 2005;165:1582–9
  • Davis SR, van der Mooren MJ, van Lunsen RH, et al Efficacy and safety of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: a randomized placebo controlled trial. Menopause 2006;13:387–96
  • Simon J, Braunstein G, Nachtigall L, et al Testosterone patch increases sexual activity and desire in surgically menopausal women with hypoactive sexual desire disorder. J Clin Endocrinol Metab 2005;90:5226–33
  • Buster J, Kingsberg SA, Aguirre O, et al Testosterone patch for low sexual desire in surgically menopausal women: a randomized trial. Obstet Gynecol 2005;105:944–52
  • Shifren JL, Davis SR, Moreau M, et al Testosterone patch for the treatment of hypoactive sexual desire disorder in naturally menopausal women: results from the INTIMATE NM1 study. Menopause 2006;13:1–10
  • Liu JH, Kingsberg K, Aguirre O, et al Treatment of naturally menopausal women with hypoactive sexual desire disorder: effect of transdermal testosterone patch in the NM2 trial. Abstract presented at the ISSWSH Meeting, 2008
  • Davis SR, Moreau M, Kroll R, et al Testosterone for low libido in postmenopausal women not taking estrogen. N Engl J Med 2008;359:2005–17
  • Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR, 4th edn. Arlington, VA: American Psychiatric Association, 2000
  • Bachmann G, Bancroft J, Braunstein G, et al Female androgen insufficiency: the Princeton consensus statement on definition, classification, and assessment. Fertil Steril 2002;77:660–5
  • Basson R, Berman J, Burnett A, et al Report of the International Consensus Development Conference on Female Sexual Dysfunction: definitions and classifications. J Urol 2000;163:888–93
  • McHorney CA, Rust J, Golombok S, et al Profile of Female Sexual Function: a patient based, international, psychometric instrument for the assessment of hypoactive sexual desire disorder. Menopause 2004;11:474–83
  • Derogatis L, Rust J, Golombok S, et al Validation of the Profile of Female Sexual Function (PFSF) in surgically and naturally menopausal women. J Sex Marital Ther 2004;30:25–36
  • Derogatis L, Rust J, Golombok S, et al A patient base diary to measure sexual activity in menopausal women with HSDD. Abstract presented at ISSWSH Meeting, 28–31, October 2004, Atlanta
  • Derogatis L, Rust J, Golombok S, et al A patient generated multinational inventory to measure distress associated with low desire. Abstract presented at ISSWSH Meeting, October 28–31, 2004, Atlanta.
  • Lorenzo EM. Familial study of hirsutism. J Clin Endocrinol 1970;31:556–64
  • Palatsi R, Hirvensalo E, Liukko P, et al Serum total and unbound testosterone and sex hormone binding globulin (SHBG) in female acne patients treated with two different oral contraceptives. Acta Derm Vernereol (Stockh) 1984;64:517–23
  • Kingsberg S, Shifren J, Derogatis L, et al Evaluation of the clinical relevance of benefits associated with transdermal testosterone treatment in post menopausal women with hypoactive sexual desire disorder. J Sex Med 2007;4:1001–8
  • Derogatis L, Graziottin A, Bitzer J, et al Clinically relevant changes in sexual desire, satisfying sexual activity and personal distress as measured by the PFSF, SAL & PDS in postmenopausal women with HSDD. J Sex Med 2009;6:175–83
  • Symonds T, Spino C, Sisson M, et al Methods to determine the minimum important difference for a sexual event diary used by postmenopausal women with hypoactive sexual desire disorder. J Sex Med 2007;4:1328–35
  • Dennerstein L, Koochaki PE, Barton IP, Graziottin A. Hypoactive sexual desire disorder in menopausal women: A survey of western European women. J Sex Med 2006;3:212–22
  • Biddle AK, West SL, D'Aloisio AA, et al Hypoactive sexual desire disorder in post menopausal women: quality of life and health burden. Value Health 2009; Jan 12. [E-pub ahead of print}
  • Leiblum SR, Koochaki PE, Rodenberg CA, Barton IP, Rosen RC. Hypoactive sexual desire disorder in post menopausal women: US results from the Women's International Study of Health and Sexuality (WISHeS). Menopause 2006;13:46–56
  • West SL, D'Aloisio AA, Agans RP, et al Prevalance of low sexual desire and hypoactive sexual desire disorder in a nationally representative sample of US women. Arch Intern Med 2008;168:1441–9
  • Hofling M, Linden Hirschberg A, Skoog L, Tani E, Hagerstrom T, von Schoultz B. Testosterone inhibits estrogen/progestogen-induced breast cell proliferation in postmenopausal women. Menopause 2007;14:1–8
  • Braunstein GD. Safety of testosterone treatment in postmenopausal women. Fertil Steril 2007;88:1–17
  • Hubayter Z, Simon JA. Testosterone therapy for sexual dysfunction. Climacteric 2008;11:181–91

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