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Research Article

ADRB3 and PPARγ2 gene polymorphisms and their association with cardiovascular disease risk in postmenopausal women

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Pages 473-478 | Received 30 Apr 2012, Accepted 28 Sep 2012, Published online: 01 Nov 2012

References

  • Beljic-Zivkovic T, Vuksanovic M, Andjelic Jelic M, et al. Obesity and metabolic syndrome during the menopause transition in Serbian women. Climacteric 2011; 14:643–8
  • Marti A, Martinez-González MA, Martinez JA. Interaction between genes and lifestyle factors on obesity. Proc Nutr Soc 2008; 67:1–8
  • Razquin C, Marti A, Martinez JA. Evidences on three relevant obesogenes: MC4R, FTO and PPARγ. Approaches for personalized nutrition. Mol Nutr Food Res 2011; 55:136–49
  • Walley AJ, Asher JE, Froguel P. The genetic contribution to non-syndromic human obesity. Nature Rev/Genetics 2009; 10: 431–42
  • Ordovas JM. Genetic influences on blood lipids and cardiovascular disease risk: tools for primary prevention. Am J Clin Nutr 2009; 89:1509–17S
  • Miyaki K, Sutani S, Kikuchi H, et al. Increased risk of obesity resulting from interaction between high energy intake and the Trp64Arg polymorphism of the beta3-adrenergic receptor gene in healthy Japanese men. J Epidemiol 2005; 15:203–10
  • Duarte SF, Francischetti EA, Genelhu VA, et al. LEPR p.Q223R p.W64R and LEP c.-2548G> A gene variants in obese Brazilian subjects. Genet Mol Res 2007; 6:1035–43
  • Ochoa MC, Marti A, Martinez JA. Obesity studies in candidate genes. Med Clin 2004; 122:542–51
  • Ochoa MC, Moreno-Aliaga MJ, Martínez-González MA, et al. TV watching modifies obesity risk linked to the 27Glu polymorphism of the ADRB2 gene in girls. Int J Pediatr Obes 2006; 1:83–8
  • Kilpeläinen TO, Lakka TA, Laaksonen DE, et al. Interaction of single nucleotide polymorphisms in ADRB2, ADRB3,TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study. Metabolism 2008; 57:428–36
  • Cecil JE, Palmer CN, Fisher B, et al. Variants of the peroxisome proliferator-activated receptor gamma- and beta-adrenergic receptor genes are associated with measures of compensatory eating behaviors in young children. Am J Clin Nutr 2007; 86:167–73
  • Dedoussis GV, Theodoraki EV, Manios Y, et al. The Pro12Ala polymorphism in PPARgamma2 gene affects lipid parameters in Greek primary school children: A case of gene-to-gender interaction. Am J Med Sci 2007; 333:10–15
  • Ochoa MC, Marti A, Azcona C, et al. Gene–gene interaction between PPARγ2 and ADRβ3 increases obesity risk in children and adolescents. Int J Obes 2004; 28:537–41
  • Garaulet M, Smith CE, Hernández-González T, et al. PPARγ Pro12Ala interacts with fat intake for obesity and weight loss in a behavioral treatment based on the Mediterranean diet. Mol Nutr Food Res 2011; 55:1771–9
  • Kurokawa N, Young EH, Oka Y, et al. The ADRB3 Trp64Arg variant and BMI: a meta-analysis of 44 833 individuals. Int J Obes 2008; 32:1240–9
  • Kilpeläinen TO, Lakka TA, Laaksonen DE, et al. SNPs in PPARG associate with type 2 diabetes and interact with physical activity. Med Sci Sports Exerc 2008; 40:25–33
  • Kurokawa N. Association of BMI with the beta3 adrenergic receptor gene mutation: a meta-analysis. Nihon Eiseigaku Zasshi 2011; 66:42–6
  • Milewicz A, Tworowska-Bardzińska U, Dunajska K, et al. Relationship of PPARγ2 polymorphism with obesity and metabolic syndrome in postmenopausal Polish women. Exp Clin Endocrinol Diabetes 2009; 117:628–32
  • Matsushita Y, Yokoyama T, Yoshiike N, et al. The Trp64Arg polymorphism of the β3-adrenergic receptor gene is not associated with body weight or body mass index in Japanese: a longitudinal analysis. J Clin Endocrinol Metab 2003; 88:5914–20
  • Shiwaku K, Nogi A, Anuurad E, et al. Difficulty in losing weight by behavioral intervention for women with Trp64Arg polymorphism of the β3-adrenergic receptor gene. Int J Obes Relat Metab Disord 2003; 27:1028–36
  • Vogels N, Mariman EC, Bouwman FG, et al. Relation of weight maintenance and dietary restraint to peroxisome proliferator activated receptor γ2, glucocorticoid receptor, and ciliary neurotrophic factor polymorphisms. Am J Clin Nutr 2005; 82:740–6
  • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin Chem 1972; 18:499–502
  • Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and b-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28:412–19
  • Karelis AD, Messier V, Brochu M, et al. Metabolically healthy but obese women: effect of an energy-restricted diet. Diabetologia 2008; 51:1752–4
  • Daniels RS, Morrison JA, Sprecher DL, et al. Association of body fat distribution and cardiovascular risk factors in children and adolescents. Circulation 1999; 99:541–5
  • Balagopal PB, de Ferranti SD, Cook S, et al. Nontraditional risk factors and biomarkers for cardiovascular disease: mechanistic, research, and clinical considerations for youth: a scientific statement from the American Heart Association. Circulation 2011; 123:2749–69
  • Lee YS. The role of genes in the current obesity epidemic. Ann Acad Med Singapore 2009; 38:45–7
  • Kang SM, Yoon JW, Ahn HY, et al. Android fat depot is more closely associated with metabolic syndrome than abdominal visceral fat in elderly people. PLoS One 2011; 6:e27694
  • Bays HE, González-Campoy JM, Bray GA, et al. Pathogenic potential of adipose tissue and metabolic consequences of adipocyte hypertrophy and increased visceral adiposity. Expert Rev Cardiovasc Ther 2008; 6:343–68
  • Bays HE. Adiposopathy is ‘sick fat’ a cardiovascular disease?J Am Coll Cardiol 2011; 57:2461–73

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