2,437
Views
50
CrossRef citations to date
0
Altmetric
Research Article

Ultra-low-dose estriol and lactobacilli in the local treatment of postmenopausal vaginal atrophy

, , , , &
Pages 347-355 | Received 05 Dec 2012, Accepted 19 Jan 2013, Published online: 04 Mar 2013

References

  • Redondo-Lopez V, Cook RL, Sobel JD. Emerging role of lactobacilli in the control and maintenance of the vaginal bacterial microflora. Rev Infect Dis 1990;12:856–72
  • McGroarty JA. Probiotic use of lactobacilli in the human female urogenital tract. FEMS Immunol Med Microbiol 1993;6: 251–64
  • Larsen B. Vaginal flora in health and disease. Clin Obstet Gynecol 1993;36:107–21
  • Stika CS. Atrophic vaginitis. Dermatol Ther 2010;23:514–22
  • Al-Baghdadi O, Ewies AA. Topical estrogen therapy in the management of postmenopausal vaginal atrophy: an up-to-date overview. Climacteric 2009;12:91–105
  • Simon JA. Vulvovaginal atrophy: new and upcoming approaches. Menopause 2009;16:5–7
  • Kanne B, Jenny J. [Local administration of low-dosed estriol and viable Lactobacillus acidophilus in the post-menopausal period]. Gynäkol Rundsch 1991;31:7–13
  • Cardozo L, Bachmann G, McClish D, Fonda D, Birgerson L. Meta-analysis of estrogen therapy in the management of urogenital atrophy in postmenopausal women: second report of the Hormones and Urogenital Therapy Committee. Obstet Gynecol 1998;92:722–7
  • Marx P, Schade G, Wilbourn S, Blank S, Moyer DL, Nett R. Low-dose (0.3 mg) synthetic conjugated estrogens A is effective for managing atrophic vaginitis. Maturitas 2004;47:47–54
  • Dessole S, Rubattu G, Ambrosini G, et al. Efficacy of low-dose intravaginal estriol on urogenital aging in postmenopausal women. Menopause 2004;11:49–56
  • Bottiglione F, Volpe A, Esposito G, Aloysio DD. Transvaginal estriol administration in postmenopausal women: a double blind comparative study of two different doses. Maturitas 1995; 22:227–32
  • Ekin M, Yasar L, Savan K, et al. The comparison of hyaluronic acid vaginal tablets with estradiol vaginal tablets in the treatment of atrophic vaginitis: a randomized controlled trial. Arch Gynecol Obstet 2011;283:539–43
  • Castelo-Branco C, Cancelo MJ, Villero J, Nohales F, Julia MD. Management of post-menopausal vaginal atrophy and atrophic vaginitis. Maturitas 2005;52(Suppl 1):S46–52
  • Vooijs GP, Geurts TBP. Review of the endometrial safety during intravaginal treatment with estriol. Eur J Obstet Gynecol 1995;62:101–6
  • Montoneri C, Zarbo G, Garofalo A, Giardinella S. Effects of estriol administration on human postmenopausal endometrium. Clin Exp Obstet Gynecol 1987;14:178–81
  • Weiderpass E, Baron JA, Adami HO, et al. Low-potency oestrogen and risk of endometrial cancer: a case-control study. Lancet 1999;353:1824–8
  • Head KA. Estriol: safety and efficacy. Altern Med Rev 1998;3: 101–13
  • Kaiser RR, Michael-Hepp J, Weber W, Graf F, Lauritzen C. Absorption of estriol from vaginal tablets after single and repeated application in healthy, postmenopausal women. Therapiewoche 2000;3:4–8
  • Ozkinay E, Terek MC, Yayci M, Kaiser R, Grob P, Tuncay G. The effectiveness of live lactobacilli in combination with low dose oestriol (Gynoflor) to restore the vaginal flora after treatment of vaginal infections. BJOG 2005;112:234–40
  • Lauritzen C, Graf F, Mucha M. [Restoration of the physiological vaginal environment with Doederlein bacteria and estriol]. Frauenarzt 1984;4:5–8
  • Feiks A, Grünberger W. [Treatment of atrophic vaginitis: does topical application allow a reduction in the oestrogen dose?]. Gynäkol Rundsch 1991;31(Suppl 2):268–71
  • Kanne B, Patz B, Wackerle L. [Local treatment of vaginal infections with Doederlein bacteria and estriol in climacterium and senium]. Frauenarzt 1986;3:35–40
  • Donders GG. Microscopy of the bacterial flora on fresh vaginal smears. Infect Dis Obstet Gynecol 1999;7:177–9
  • Genazzani AR, Inaudi P, la Rosa R, et al. Oestriol and the menopause: clinical and endocrinological results of vaginal administration. In Fioretti P, Martini L, Melis GB, Yen SSC, eds. The Menopause: Clinical, Endocrinological and Pathophysiological Aspects. London: Academic Press, 1982:539–50
  • Griesser H, Skonietzki S, Fischer T, Fielder K, Suesskind M. Low dose estriol pessaries for the treatment of vaginal atrophy: A double-blind placebo-controlled trial investigating the efficacy of pessaries containing 0.2mg and 0.03mg estriol. Maturitas 2012;71:360–8
  • Sturdee DW, Panay N. Recommendations for the management of postmenopausal vaginal atrophy. Climacteric 2010;13:509–22
  • Kanne B, Patz B, Wackerle L. Local treatment of vaginal infections with Doederlein bacteria and estriol in climacterium and senium. Frauenarzt 1986;3:35–40
  • Kanne B. Local administration of weakly dosed estriol and active Lactobacillus acidophilus in the postmenopausal period. Arch Gynecol Obstet 1989;246(Suppl):134
  • Kanne B, Jenny J. Local administration of low-dosed estriol and viable Lactobacillus acidophilus in the post-menopausal period. Gynäkol Rundsch 1991;31:1–8