References
- World Cancer Report. International Agency for Research on Cancer, 2008. http://globocan.iarc.fr/factsheets/populations/factsheet.asp?uno = 900. Accessed 26.2.2011
- Breast cancer: prevention and control. World Health Organization. http://www.who.int/cancer/ detection/ breastcancer/en/index1.html
- Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women. JAMA 2002;288:321–33
- Million Women Study Collaborators. Breast cancer and hormone replacement therapy in the Million Women Study. Lancet 2003;362:419–27
- Fournier A, Berrino F, Clavel-Chapelon F. Unequal risks for breast cancer associated with different hormone replacement therapies: results from the E3N cohort study. Breast Cancer Res Treat 2008;107:103–11
- Fournier A, Mesrine S, Boutron-Ruault M-C, Clavel-Chapelon F. Estrogen-progestagen menopausal hormone therapy and breast cancer: does delay from menopause onset to treatment initiation influence risks?. J Clin Oncol 2009;27:5138–43
- The Women's Health Initiative Steering Committee. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy. JAMA 2004;291:1701–12
- Schoonen WGEJ, Joosten JWH, Kloosterboer HJ. Effects of two classes of progestins, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells. 1. MCF-7 cell lines.. J Steroid Biochem Mol Biol 1995;55:423–37
- Cappelletti V, Miodini P Fioravanti L, DiFronzo G. Effect of progestin treatment on estradiol- and growth factor-stimulated breast cancer cell lines. Anticancer Res 1995;15:2551–6
- Krämer EA, Seeger H, Krämer B, Wallwiener D, Mueck AO. The effect of progesterone, testosterone and synthetic progestins on growth factor- and estradiol-treated human cancerous and benign breast cells. Eur J Obstet Gynecol Reprod 2006;27:139–41
- Africander D, Verhoog N, Hapgood JP. Molecular mechanisms of steroid receptor-mediated actions of synthetic progestins used in HRT and contraception. Steroids 2011;76:636–52
- Neubauer H, Adam G, Seeger H, et al.Membrane-initiated effects of progesterone on proliferation and activation of VEGF in breast cancer cells. Climacteric 2009;3:230–9
- Neubauer H, Chen R, Schneck H. New insight on a possible mechanism of progestins in terms of breast cancer risk. Horm Mol Biol Clin Invest 2011;6:185–92
- Ruan X, Neubauer H, Yang Y, et al.Progestins and membrane-initiated effects on the proliferation of human breast cancer cells. Climacteric 2012;15:467–72
- Neubauer H, Yang Y, Seeger H. The presence of a membrane-bound progesterone receptor sensitizes the estradiol-induced effect on the proliferation of human breast cancer cells. Menopause 2011;8:845–50
- Ruan X, Schneck H, Schultz S, et al.Nomegestrol acetate sequentially or continuously combined to estradiol did not negatively affect membrane-receptor associated progestogenic effects in human breast cancer cells. Gynecol Endocrinol 2012; 28:863–6
- Stanczyk FZ. Can the increase in breast cancer observed in the estrogen/progestin arm of the WHI Trial be explained by PGRMC1?. Menopause 2011;18:833–4
- Cahill MA. Progesterone receptor membrane component 1: an integrative review. J Steroid Biochem Mol Biol 2007;105:16–36
- Meyer C, Schmid R, Scriba PC, Wehling M. Purification and partial sequencing of high-affinity progesterone-binding site(s) from porcine liver membranes. Eur J Biochem 1996;239:726–33
- Hughes AL, Powell DW, Bard M, et al.Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes. Cell Metab 2007; 5:143–9
- Intlekofer KA, Petersen SL. Distribution of mRNAs encoding classical progestin receptor, progesterone membrane components 1 and 2, serpine mRNA binding protein 1, and progestin and adipoQ receptor family members 7 and 8 in rat forebrain. Neuroscience 2011;172:55–62
- Krebs CJ, Jarvis ED, Chan J, Lydon JP, Ogawa S, Pfaff DW. A membrane-associated progesterone binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors. Proc Natl Acad Sci USA 2000;97: 12816–21
- Labombarda F, Gonzalez SL, Deniselle MC, et al.Effects of injury and progesterone treatment on progesterone receptor and progesterone binding protein 25-Dx expression in the rat spinal cord. J Neurochem 2003;87:902–13
- Correia JN, Conner SJ, Kirkman-Brown JC. Non-genomic steroid actions in human spermatozoa. “Persistent tickling from a laden environment.”. Semin Reprod Med 2007;25:208–19
- Peluso JJ, Liu X, Gawkowska A, Johnston-MacAnanny E. Progesterone activates a progesterone receptor membrane component 1-dependent mechanism that promotes human granulosa/luteal cell survival but not progesterone secretion. J Clin Endocrinol Metab 2009;94:2644–9
- Cai Z, Stocco C. Expression and regulation of progestin membrane receptors in the rat corpus luteum. Endocrinology 2005;146:5522–32
- Magdalena K. Kowalik, Jan Kotwica. Progesterone receptor membrane component 1 (PGRMC1) gene expression in corpus luteum during the estrous cycle in cows. Reprod Biol 2008; 8:291–7
- Neubauer H, Clare SE, Wozny W, et al.Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1. Breast Cancer Res 2008;10:R85
- Crudden G, Loesel R, Craven RJ. Overexpression of the cytochrome p450 activator hpr6 (heme-1 domain protein/human progesterone receptor) in tumors. Tumour Biol 2005;26:142–6
- Ji SF, Wu AG, Yang HF. Expression of progesterone receptor membrane component-1 is associated with the malignant phenotypes of breast cancer. Nan Fang Yi Ke Da Xue Xue Bao 2012;32:635–8
- Causey MW, Huston LJ, Harold DM, et al.Transcriptional analysis of novel hormone receptors PGRMC1 and PGRMC2 as potential biomarkers of breast adenocarcinoma staging. J Surg Res 2011;171:615–22
- Lundgren K, Holm C, Landberg G. Hypoxia and breast cancer: prognostic and therapeutic implications. Cell Mol Life Sci 2007,64:3233–47
- Peluso JJ, Gawkowska A, Liu X, Shioda T, Pru JK. Progesterone receptor membrane component-1 regulates the development and cisplatin sensitivity of human ovarian tumors in athymic nude mice. Endocrinology 2009;150:4846–54
- Swiatek-De Lange M, Stampfl A, Hauck SM, et al.Membrane-initiated effects of progesterone on calcium dependent signaling and activation of VEGF gene expression in retinal glial cells. Glia 2007;55:1061–73
- Liang Y, Besch-Williford C, Brekken RA, Hyder SM. Progestin dependent progression of human breast tumor xenografts: a novel model for evaluating antitumor therapeutics. Cancer Res 2007;67:9929–36
- Neubauer H, Schneck H, Seeger H, et al.Overexpression of progesterone receptor membrane component 1 – possible mechanism for increased breast cancer risk using norethisterone in hormone therapy. Menopause 2013;20:504–10
- Hand RA, Craven RJ. Hpr6.6 protein mediates cell death from oxidative damage in MCF-7 human breast cancer cells. J Cell Biochem 2003;90:534–47
- Olsen JV, Blagoev B, Gnad F, et al.Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell 2006;127:635–48
- Liu L, Wang J, Zhao L, et al.Progesterone increases rat neural progenitor cell cycle gene expression and proliferation via extracellularly regulated kinase and progesterone receptor membrane components 1 and 2. Endocrinology 2009;150: 3186–96
- Suchanek M, Radzikowska A, Thiele C. Photo-leucine and photo-methionine allow identification of protein–protein interactions in living cells. Nat Methods 2005;2:261–7
- Lee JN, Song B, DeBose-Boyd RA, Ye J. Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78. J Biol Chem 2006;281:39308–15
- Song BL, DeBose-Boyd RA. Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase. J Biol Chem 2004;279:28798–806
- Ahmed IS, Rohe HJ, Twist KE, Craven RJ. Pgrmc1 (progesterone receptor membrane component 1) associates with epidermal growth factor receptor and regulates erlotinib sensitivity. J Biol Chem 2010;285:24775–82
- Mir SU, Ahmed IS, Arnold S, Craven RJ. Elevated progesterone receptor membrane component 1/sigma-2 receptor levels in lung tumors and plasma from lung cancer patients. Int J Cancer 2012;131:E1–9