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Archives of Physiology and Biochemistry
The Journal of Metabolic Diseases
Volume 118, 2012 - Issue 5
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Original Article

Effect of carnosine on erythrocyte deformability in diabetic rats

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Pages 265-272 | Received 17 Apr 2012, Accepted 18 Jul 2012, Published online: 05 Sep 2012

References

  • Aguirre F, Martin I, Grinspon D, Ruiz M, Hager A, De Paoli T, Ihlo J, Forach A, Poole CP Jr (1998). Oxidative damage, plasma antioxidant capacity, and glucemic control in elderly NIDDM patients. Free Radic Biol Med 24 (4): 580–5.
  • Ahmet AM. (2002). History of diabetes mellitus. Saudi Med J 23:373–8.
  • Alaghband–Zadeh J, Mehdizadeh S, Khan NS, O’Farrel A. (2001). The natural substrate for nitric oxide synthase activity. Cell Biochem 19:277–80.
  • Allen H, Allen JC, Boyd LC, Alston-Mills BP, Fenner GP. (2006). Determination of membrane lipid differences in insulin resistant diabetes mellitus type 2 in whites and blacks. Nutrition 22:1096–1102.
  • Arto K, Sandra T. (1996). The calcium dependent nitric oxide production of human vascular endothelial cell in preeclampsia. Am J Obstet Gynecol 174:1056–60.
  • Aydin A, Orhan H, Sayal A, Ozata M, Sahin G, Işimer A. (2001). Oxidative stress and nitric oxide related paremeters in type II diabetes mellitus: effects of glycemic control. Clin Biochem34:65–70.
  • Aydogan S, Yapislar H, Artis S. (2008). Impaired erythrocyte deformability in H2O2 induced oxidative stress: protective effect of carnosine. Clin Hemorheol Microcirc 39:93–8.
  • Bitar MS, Wahid S, Mustafa S, Saleh E, Dhaunsi G, Mulla F. (2005). Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes. Eur J Pharmacol 511:53–64.
  • Brown C, Ghali H, Zhao Z, Thomas L, Friedman E. (2005). Association of reduced red blood cell deformability with diabeti nephropathy. Kidney Int 67:295–300.
  • Ceriello A, Bortolotti N, Crescentini A, Motz E, Lizzio S, Russo A, Ezsol Z, Tonutti L, Taboga C (1998). Anti-oxidant defences are reduced during the oral glucose tolerance test in normal and non-insulin-dependent diabetic subjects. Eur J Clin Invest 28:323–33.
  • Chiarelli F, Cipollone F, Romano F, Tumini S, Constantini F, di Ricco L, Pomilio M, Pierdomenico SD, Marini M, Cuccurullo F et al. (2000). Increased circulating nitric oxide in young patients with type I diabetes and persistant microalbuminuria, relation to glomerular hyperfiltration. Diabetes 49:1258–63.
  • Chien S. (1970). Shear dependence of effective cell volume as a determinant of blood viscosity. Science 168:977–9.
  • Chiu DTY, Lubin B, Shohet SB. (1982). Peroxidative reactions in red cell biology. Free Radicals in Biology. New York: Academic Press, 115–60.
  • Cosentino F, Hishikawa K, Katusic ZS, Luscher TF. (1997). High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cell. Circulation 96:25–8.
  • Craven PA, DeRubertis FR. (1989). Protein kinase C is activated in glomeruli from streptozotocin diabetic rats. Possible mediation by glucose. J Clin Invest 83:1667–75.
  • Garnier M, Attali JR, Valensi P. Delatour Hanns E. (1990). Erythrocyte deformability in diabetes and erythrocyte membrane lipid composition. Metabolism 38:794.
  • Giugliano D, Ceriello A, Paolisso G. (1996). Oxidative stress and diabetic vascular complications. Diabetes Care 39:257–267.
  • Godin DV, Wohaieb SA, Garnett ME, Goumenlouk AD. (1988). Anti–oxidant enzyme alterations in experimental and clinical diabetes. Mol Cell Biochem 84:223–31.
  • Gupta S, Sussman I, McArthur CS, Tornheim K, Cohen RA, Ruderman NB, (1992). Endothelium dependent inhibition of Na/K ATPase activity in rabbit aorta by hyperglycemia. Possible role of endothelium derived nitric oxide. J Clin Invest 90:727–32.
  • Hink U, Li H, Mollnau H, Oelze M, Matheis E, Hartmann M, Skatchov M, Thaiss F, Stahl RA, Warnholtz A, et al. (2001). Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res 88:14–22.
  • Hogg N, Kalyanaraman B. (1999). Nitric oxide and lipid peroxidation. Biochim Biophys Acta 1411:378–84.
  • Inouye M, Mio T, Sumino K. (1999). Glycated hemoglobin and lipid peroxidation in erythrocytes of diabetic patients. Metabolism 48:205–9.
  • Jain SJ, Levine SN, Duett J, Hallier B. (1990). Elevated lipid peroxidation levels in red blood cells of streptozotocin treated diabetic rats. Metabolism 39:971–5.
  • Kaneto H, Kajimoto T, Matsuzawa Y, Yamasaki Y, Hori M. (1999). Benefical effects of anti-oxidants in diabetes. Diabetes 48:2398–406.
  • Kanner J, Harel S, Granit R. (1991). Nitric oxide as an anti-oxidant. Arch Biochem Biophys 289:130–36.
  • Kedziora-Kornatowska KA, Luciak M, Blaszczyk Pawlak W. (1998). Lipid peroxidation and activities of anti-oxidant enzymes in erythrocytes of patients with non-insulin depedent diabetes mellitus with of without nephropathy. Nephrol Dial Transplant 13:2829–32.
  • Kekow J, Ulrichs K, Müller-Ruchholtzw W, Gross WL. (1988). Measurement of rat insulin: enzyme-linked immunosorbent assay with increased sensitivity, high accuracy, and greater practicability than established radioimmunoassay. Diabetes 37:321–6.
  • Kiechle F, Malinski T. (1993). Nitric oxide: Biochemistry, pathophysiology and detection. Clin Chem 100:567–75.
  • Khoschsorur GA, Winklhofer BM, Rabl H, Auer T, Peng Z, Schaur J. (2000). Evaluation of a sensitive HPLC method for the determination of Malondialdehyde, and application of the method to different biological materials. Chromatographia 52:1612–1112.
  • Korobov VN, Maurisio RB, Mukalov IO, Stvolinski SL. (2000). Carnosine stabilization of the normal erythrocyte membranes and in experimental diabetes. Patol Fiziol Eksp Ter 2:13–15.
  • Kurealla EG, Maltseva VV, Seslavina LS, Stvolinskii SL. (1991). Stimulating action of carnosine on hematopoietic stem cells. Bull Exp Biol Med 112:966–8.
  • Küçükatay MB, Wenby RB, Meiselman HJ, Baskurt OK. (2003). Effects of nitric oxide on red blood cell deformability. Am J Physiol Heart Circ Physiol 284:1577–84.
  • Kuboki K, Jiang ZY, Takahara N, Ha SW, Igarashi M, Yamauchi T, Feener EP, Herbert TP, Rhodes CJ, King GL. (2000). Regulation of endothelial constitutive nitric oxidde synthase gene expresion in endothelial cells and in vivo: a specific vascular action of insulin. Circulation 101:676–681.
  • Lo HC, Lin SC, Wayn YM. (2004). The relationship among serum cytokines, chemokine, nitric oxide and leptin in children with type 1 diabetes mellitus. Clin Biochem 37:666–72.
  • Lubin B, Chiu DTY. (1982). Properties of vitamin E-deficient erythrocytes following peroxidant injury. Pediatr Res 16:928–32.
  • Maritim AC, Sanders RA, Watkins III JB. (2003). Diabetes, oxidative stress and anti–oxidants, review. J Biochem Mol Toxicol 17:4–38.
  • Marjani A. (2010). Lipid peroxidation alterations in type 2 diabetic patients. Pak J Biol Sci 13:723–730
  • Martinez M, Veya A, Server R, Santaolaria M, Aznar J. (1998). Erythrocyte elongation index measured on a Rheodyn SSD laser diffractometer. Influence of the hematocrit. Clin Hemorheol Microcirc 19:255–7.
  • Maxwell SRJ, Thomason H, Sandler D, Baxter MA, LeGuen C, Baxter MA, Thorpe GL, Jones AF, Barnett AH (1997). Poor glycaemic control is associated with reduced serum free radical scavenging (antioxidant) activity in NIDDM. Ann Clin Biochem 34:638–644.
  • Mazzanti L, Faloia E, Rabini RA, Staffolani R, Kantar A, Fiorini R, Swoboda B, De Pirro R, Bertoli El. (1992). Diabetes mellitus induces red blood cell plasma membrane alterations possibly affecting the aging process. Clin Biochem 25:41–46.
  • Mohan A, Srinivasan V, Deepa R, Mohan V. (2001). Lipoprotein (a): role in diabetes and its vascular complications. J Assoc Physicians India 49:1100–105.
  • Mokken FH, Kaderia M, Henny CP, Haredeman MR, Gelb AW. (1992). The clinical importance of erythrocyte deformability, a hemorheological parameter. Ann Hematol 64:113–22.
  • Mol MJ, Rijke YB, Demecker PN, Stalenhoef AF. (1997). Plasma levels of lipid and cholesterol oxidation products and cytokines in diabetes mellitus and cigarette smoking: effects of vitamin E treatment. Atherosclerosis 129:169–76.
  • Paolisso G, D’Amore A, Balbi V, Volpe C, Galzerano D, Giugliano D, Sgambato S, Varricchio M, D’Onofrio F. (1994). Plasma vitamin C affects glucose homeostasis in healthy subjects and in NIDDM. Am J Physiol 266:261–268.
  • Prokopieva VD, Bohan NA, Johnson P, Abe H, Boldyrev AA. (2000). Effects of carnosine and related compounds on the stability and morphology of erythrocytes from alcoholics. Alcohol Alcoholism 35:44–8.
  • Quinn PJ, Boldyrev AA, Formazuyk VE. (1992). Carnosine: its properties, function and potential therapeutic applications. Mol Aspects Med 13:379–444.
  • Rabini RA, Fumelli P, Staffolani R, Mazzanti L, Pugnaloni A, Biagini G, Faloia F, De Pirro R. (1993). Effect of diabetes mellitus on structural and functional properties of erythrocyte membranes. Membr Biochem 10:71–79.
  • Rubbo H, Batthyhany C, Radi R. (2000). Nitric oxide-oxygen radicals interactions in atherosclerosis. Biol Res 33:167–75.
  • Ruiz C, Alegria A, Barbera R, Farre R, Lagarda MJ. (1999). Lipid peroxidation and anti-oxidant enzyme activities in patients with type I diabetes mellitus. Scand J Clin Lab Invest 59:99–105.
  • Schemetterer L, Findl O, Fasching P, Ferber W, Strenn K, Breiteneder H, Adam H, Eichler HG, Wolzt M. (1997). Nitric oxide and ocular blood flow in patients with IDDM. Diabetes 46:653–8.
  • Shin S, Ku YH, Suh JS, Singh M. (2008). Rheological characteristics of erythrocytes incubated in glucose media. Clin Hemorh and Microcirc 38:153–61.
  • Singh VP, Jam NK, Kulkarni SK. (2003). Fluoxetine suppresses morphine tolerance and dependence: Modulation of NO-cGMP/DA/serotoninergic pathways. Methods Find Exp Clin Pharmacol 25:273–80.
  • Smits P, Hersbach FMRJ, Jansen TLTA, Thien J, Lutterman JA. (1993). Impaired vasodilator response to atrial natriuretic factor in IDDM. Diabetes 42:1454–61.
  • Szkudelski T. (2001). The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res 50:536–46.
  • Sun MF, Wen YR, Kua PL, Liu CF. (2005). Elevated nitric oxide levels inhibit malondialdehyde production in patients with diabetes mellitus in Taiwan. Nutr Met Car Dis 15:452–3.
  • Takahashi S, Nakashima Y, Toda K. (2009). Carnosine facilitates nitric oxide production in endothelial f-2 cells. Biol Pharm Bull 32:1836–9.
  • Tavazzi B, Pierro D, Amorini AM, Fezzina G, Tuttobene M, Giardina B. (2000). Energy metabolism and lipid peroxidation of human erythrocytes as a function of increased oxidative stress. Eur J Biochem 267:684–9.
  • Testa I, Mantrini S, Gregorio A, Refe A, Bonfigli AR, Testa R, Piantanelli L. ((2003)). Red blood cell deformability in diabetic retinopahty. Biorheology 32:389.
  • Tomonaga S, Tachibana T, Takahashi H, Sato M, Denbow DM, Furuse M. ((2005)). Nitric oxide involves in carnosine induced hyperactivity in chicks. Eur J Pharmacol 524:84–88.
  • Vague P, Dufayet D, Lamotte M, Mouchot C, Raccah D. (1992). Genetic factors, Na+/K+-ATPase activity in the red cell membrane, a potential marker of the predisposition to diabetic neuropathy. Diabetes Metab 18:236–41.
  • Vanizor B, Orem A, Karahan SC, Kiran E, Erem C, Aliyazicioglu R, Uydu HA. (2001). Decreased nitric oxide and products and its relationship with high density lipoprotein and oxidative stress in people with type 2 diabetes without complications. Diabetes Res Clin Prac 54:33–9.
  • van Dam B, Demirci C, Reitsma HJ, van Lambalgen AA, van den Bos GC, Tangelder GJ, Stehouwer CD. (2002). Arteriolar changes in nitric oxide activity and sensitivity during the course of streptozotocin-induced diabetes. Eur J Pharmacol 455:43–51.
  • Varvarovska J, Racek J, Stozicky F, Soucek L, Trefil R. (2003). Parameters of oxidative stress in children with type I diabetes mellitus and their relatives. J Diabetes Complications 17:7–10.
  • Vijayalingam S, Parthiban A, Shanmugasundaram KR, Mohan V. (1996). Abnormal anti-oxidant status in impaired glucose tolerance and non-insulin-dependent diabetes mellitus. Diabetic Med 13:715–19.
  • Weed RI. (1970). The importance of erythrocyte deformability. Am Jour Med 49:147–50.
  • Wolff SP, Dean RT. (1987). Glucose autoxidation and protein modification. The potential role of autoxidative glycosylation in diabetes. Biochem J 245:245–50.
  • Yang ZC, Xia K, Wang L, Jia SJ, Li D, Zhang Z, Deng S, Zhang XH, Deng HW, Li YJ. (2007). Asymmetric dimethylarginine reduced erythrocyte deformability in streotozotocin–induced diabetic rats. Microvasc Res 73:131–136.
  • Yapislar H, Aydogan S, Borlu M, Ascioglu O. (2007). Decreased nitric oxide and increased platelet aggregation levels in patients with Behçet’s disease. Thromb Res 119:461–465.

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