926
Views
15
CrossRef citations to date
0
Altmetric
Research Article

Immunomodulatory effects of damnacanthal isolated from roots of Morinda elliptica

, , , , &
Pages 446-452 | Received 04 Jul 2008, Accepted 04 Feb 2009, Published online: 24 Mar 2010

References

  • Adam JK, Odhav B, Bhoola KD (2003): Immune responses in cancer. Pharmacol Ther 99: 113–132.
  • Ali AM, Ismail N, Mackeen M, Yazan L, Mohamed S, Ho A, Lajis N (2000): Antiviral, cytotoxic and antimicrobial activities of antharaquinones isolated from the roots of Morinda elliptica. Pharm Biol 38: 3791–3801.
  • Aoki K, Parent A, Zhang J (2000): Mechanism of damnacanthal-induced [Ca(2+)] (i) elevation in human dermal fibroblasts. Eur J Pharm 387: 119–124.
  • Bryan DL, Forsyth KD, Gibson RA, Hawkes JS (2006): Interleukin-2 in human milk: A potential modulator of lymphocyte development in breastfed infant. Cytokine 33: 289–293.
  • Cerqueira F, Cordeiro-Da-Silva A, Gaspar-Marques C, Simoes F, Pinto MMM, Nascimento MSJ (2004): Effect of abietane diterpenes from Plectranthus grandidentatus on T- and B-lymphocytes proliferation. Bioorg Med Chem 12: 217–223.
  • Chandok MR, Farber DL (2004): Signalling control of memory T cell generation and function. Semin Immunol 16: 285–293.
  • Farag SS, Caliguiri MA (2006): Human natural killer cells development and biology. Blood Rev 20: 123–137.
  • Hiramatsu T, Imato M, Koyono T, Umezawa K (1993): Induction of normal phenotypes in Ras transformed cells by damnacanthal from Morinda citrifolia. Cancer Lett 73: 161–166.
  • Hirazumi A, Furusawa E, Chou SC, Hokama Y (1994): Anti-cancer activity of Morinda citrifolia on intraperitoneally implanted Lewis lung carcinoma in syngenic mice. Proc West Pharmacol Soc 37: 145–146.
  • Hirazumi A, Furusawa E, Chou SC, Hokama Y (1996): Immunomodulation contributes to the anti-cancer activity of Morinda citrifolia (noni) fruit juice. Proc West Pharmacol Soc 39: 7–9.
  • Hirazumi A, Furusawa E, Chou SC, Hokama Y (1999): Immunomodulatory polysaccharide-rich substances from the fruit juice of Morinda citrifolia (noni) with anti-tumor activity. Phytother Res 13: 380–387.
  • Hiwasa T, Arase Y, Chen Z, Kita K, Umezawa K, Ito H, Suzuki N (1999): Stimulation of ultraviolet-induced apoptosis of human fibroblast UV-1 cells by tyrosine kinase inhibitors. FEBS Lett 444: 173–176.
  • Ismail NH, Ali AM, Aimi N, Kitajima M, Takayama H, Lajis NH (1997): Anthraquinones from Morinda elliptica. Phytochemistry 45: 1723–1725.
  • Jasril K, Nordin HL, Lim YM, Abdullah MA, Sukari MA, Ali MA (2003): Antitumor promoting and antioxidant activities of anthraquinones isolated from the cell suspension culture of Morinda elliptica. Asia Pac J Mol Biol Biotechnol 11: 3–7.
  • Kwanjai K, Somdej K, Ruchanee P (2005): Biological activity of anthraquinones and triterpenoids from Prismatomeris fragrans. J Ethnopharmacol 100: 184–288.
  • Li J, Li Q, Feng T, Li K (2008): Aqueous extract of Solanum nigrum inhibit growth of cervical carcinoma (U14) via modulating immune response of tumor bearing mice and inducing apoptosis of tumor cells. Fitoterapia 79: 548–556.
  • Loken MR (1980): Simultaneous quantitation of Hoechst 33342 and immunofluorescence on viable cells using a fluorescence activated cell sorter. Cytometry 1: 136–142.
  • Manosroi A, Saraphanchotiwitthaya A, Manosroi J (2003): Immunomodulatory activities of Clausena excavata Burm. f. wood extracts. J. Ethnopharmacol 89: 155–160.
  • Manuele MG, Ferraro G, Barreiro Arcos ML, López P, Cremaschi G, Anesini C (2006): Comparative immunomodulatory effect of scopoletin on tumoral and normal lymphocytes. Life Sci 79: 2043–2048.
  • Masakazu K, Raymond PW, Dong SA, Jonathan PS, Robert D, Micheal EP, Jing H, Irvin, SYC (2006): Cell-based chemical genetic screen identifies damnacanthal inhibitor of HIV-Vpr induced cell death. Biochem Biophys Res Comm 384: 1101–1106.
  • Mosmann T (1983): Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxic assay. J Immunol Methods 65: 55–63.
  • Ong HC, Norzalina J (1999): Malay herbal medicine in Gemencheh, Negeri Sembilan, Malaysia. Fitoterapia 70:10–14.
  • Stanilove SA, Dobreva ZG, Slavov ES, Mitera LD (2005): C3 binding glycoprotein from Cuscuta europea induced different cytokine profile from human PBMC compared to other plant and bacteria immunomodulators. Int Immunopharmacol 5: 727–734.
  • Tosa H, Ilnuma M, Asai F, Tanaka T, Nozaki H, Fujimori S (1998): Anthraquinones from Neonauclea calycina and their inhibitory activity against DNA topoisomerase II. Biol Pharm Bull 21: 641–642.
  • Wang MY, Su C (2001): Cancer preventive effect of Morinda citrifolia (noni). Ann NY Acad Sci 952: 161–168.
  • Wang MY, West B, Jensen CJ, Nowicki D, Su C, Palu AK, Anderson G (2002): Morinda citrifolia (noni): A literature review and recent advances in noni research. Acta Pharmacol Sin 23: 1127–1141.
  • Zhao M, Yang B, Wang J, Liu Y, Yu L, Jiang Y (2007): Immunomodulatory and anticancer activities of flavonoids extracted from litchi (Litchi chinensis Sonn.) pericarp. Int Immunopharmacol 7: 162–177.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.