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Research Article

Tegillarca granosa extract Haishengsu inhibits the expression of p-glycoprotein and induces apoptosis in drug-resistant K562/ADM cells

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Pages 529-533 | Received 12 Sep 2008, Accepted 12 Feb 2009, Published online: 17 Mar 2010

References

  • Boatright KM, Salvesen GS (2003): Mechanisms of caspase activation. Curr Opin Cell Biol 15: 725–731.
  • Cohen GM (1997): Caspases: The executioners of apoptosis. Biochem J 326: 1–16.
  • Ford JP, Hoggard G, Owen A, Khoo SH, Back DJ (2003): A simplified approach to determining p-glycoprotein expression in peripheral blood mononuclear cell subsets. J Immunol Methods 274: 129–137.
  • Gupta S, Afaq F, Mukhtar H (2002): Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells. Oncogene 21: 3727–3738.
  • Higgins CF (1992): ABC transporters: From microorganisms to man. Annu Rev Cell Biol 8: 67–113.
  • Klein E, Ben-Bassat H, Neumann H, Ralph P, Zeuthen J, Polliack A, Vanky F (1976): Properties of the K562 cell line, derived from a patient with chronic myeloid leukemia. Int J Cancer 18: 421–431.
  • Jung WK, Jo HY, Qian ZJ, Jeong YJ, Park SG, Choi IW, Kim SK (2007): A novel anticoagulant protein with high affinity to blood coagulation factor Va from Tegillarca granosa. J Biochem Molecular Biol 40: 832–838.
  • Kantarjian HM, Talpaz M, Giles F, O’Brien S, Cortes J (2006): New insights into the pathophysiology of chronic myeloid leukemia and imatinib resistance. Anna Intern Med 145: 913–923.
  • Li GY, Liu JZ, Yu XM, Chen SF, Zhang B, Zhang WF, Wang LX (2008): Effect of a seashell protein haishengsu on cell growth and expression of apoptosis genes in leukemia K562 Cells. Clin Invest Med 31: E218–E221.
  • Li GY, Yu XM, Zhang HW, Zhang B, Wang CB, Xin YC, Yang CZ, Zhou RX, Wang LX (2008): Haishengsu as an adjunct therapy to conventional chemotherapy in patients with non-small cell lung cancer: A pilot randomized and placebo-controlled clinical trial. Complement Ther Med 2009; 17: 51–55.
  • Liu ZX, Zhan SM, Yao RY, Fang LH, Yang X, Wang CB (2004): An experimental study on anti-tumor effect of Haishengsu injection. Chin J Mar Drugs 23: 35–37.
  • Tsuruo T, Iida-Saito H, Kawabata H, Oh-hara T, Hamada H, Utakoji T (1986): Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones. Jpn J Cancer Res 77: 682–692.
  • Wang ZL, Chu X, Yang X, Chen SQ, Wang CB (2006): Antitumor effects of extractive from Arca granosa Linnaeus. Shandong Med J 46: 69–73.
  • Yang CZ, Luan FJ, Xiong DS, Liu BR, Xu YF, Gu KS (1995): Multidrug resistance in leukemic cell line K562/A02 induced by doxorubicin. Acta Pharmacol Sin 16: 333–337.
  • Yao RY, Chu X, Zhang YJ, Yang X, Liu XR, Wang CB (2005): Anti-tumor effect of Haishengsu extracted from Tegillarca granosa in vitro and in vivo. Chin J Mar Drugs 24: 33–36.
  • Zhang CX, Li GY, Han CS, Ye XQ, Chen HY, Zhou HJ, Chen SG (2005): Effect of Haishengsu preparation extracted from Tegillarca granosa in treatment of intermediate and late non-small-cell lung cancer (NSCLC) and late renal cancer. Chin J Mar Drugs 24: 55–58.

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