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Research Article

Antidiabetic effect of Dodonaea viscosa aerial parts in high fat diet and low dose streptozotocin-induced type 2 diabetic rats: A mechanistic approach

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Pages 1137-1148 | Received 30 Apr 2009, Accepted 03 Dec 2009, Published online: 03 Sep 2010

References

  • Aswal BS, Bhakuni DS, Goel AK, Kar K, Mehrotra BN (1984): Screening of Indian plants for biological activity- Part XI. Ind J Exp Biol 22: 487–504.
  • Basciano H, Federico L, Adeli K (2005): Fructose, insulin resistance and metabolic dyslipidemia. Nutr Metab 2: 1–5.
  • Berger J, Bailey P (1996): Thiazolidinediones produce conformational changes in peroxisome proliferator activated receptor gamma: Binding and activation correlate with antidiabetic actions in db/db mice. Endocrinology 137: 4189–4195.
  • Friedewald WT, Levy RI, Fredrickson DS (1972): Estimation of low-density lipoprotein cholesterol in plasma, without use of the preparative centrifuge. Clin Chem 18: 499–501.
  • Gelvan D, Saltman P (1990): Different cellular targets of Cu- and Fe-catalyzed oxidation observed using a Cu-compatible thiobarbiturate acid assay. Biochim Biophys Acta 1035: 353–360.
  • Getie M, Gebre-Mariam T, Rietz R, Hohne C, Huschka C, Schmidtke M, Abate A, Neubert RH (2003): Evaluation of the anti-microbial and anti-inflammatory activities of the medicinal plants Dodonaea viscosa, Rumex nervosus and Rumex abyssinicus. Fitoterapia 74: 139–143.
  • Ghosh R, Sharatchandra KH, Rita S, Thokchom IS (2004): Hypoglycemic activity of Ficus hispida (bark) in normal and diabetic rats. Ind J Pharmacol 36: 222–225.
  • Hevener A, Reichart D, Janez A, Olefsky J (2002): Female rats do not exhibit free fatty acid-induced insulin resistance. Diabetes 51: 1907–1912.
  • Ji-Hu Z, Chung TDY, Oldenburg KR (1999): A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 4: 67–73.
  • Joshi SD, Badiger AM, Ashok K, Veerapur VP, Shastry CS (2003): Wound healing activity of Dodonaea viscosa leaves. Ind Drugs 40: 549–552.
  • Kirtikar KR, Basu BD (1993): Indian Medicinal Plants, second edition. Vol. I. Dehradun, India, International Book Publisher.
  • Korcsmaros T, Szalay MS, Böde C, Kovács IA, Csermely P (2007): How to design multi-target drugs: Target search options in cellular networks. Expert Opinion Drug Discov 2: 1–10.
  • Laville M, Auboeuf D, Khalfallah Y, Vega N, Riou JP, Vidal H (1996): Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, GLUT 4, and lipoprotein lipase mRNA levels in human muscle. J Clin Invest 98: 43–49.
  • Lowry OH, Rosenhrough NJ, Farr AL, Randall RJ (1951): Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265–275.
  • Mahesh T, Venugopal PM (2004): Quercetin alleviates oxidative stress in streptozotocin-induced diabetic rats. Phytother Res 18: 123–127.
  • Markham KR (1982): Techniques of Flavonoid Identification. London, Academic Press.
  • Perry LM, Metzger J (1980): Medicinal Plants of East Southeast Asia. Cambridge, MA and London, MIT Press.
  • Petersen KF, Krssak M, Inzucchi S, Cline GW, Dufour S, Shulman GI (2000): Mechanism of troglitazone action in type 2 diabetes. Diabetes 49: 827–831.
  • Prabhakar KR, Veerapur VP, Parihar KV, Priyadarsini KI, RAO BS, Unnikrishnan MK (2006): Evaluation and optimization of radioprotective activity of Coronopus didymus Linn. in gamma-irradiated mice. Int J Rad Biol 82: 525–536.
  • Rajas A, Cruz S, Ponce-Monter H, Mata R (1996): Smooth muscle relaxing compounds from Dodonaea viscosa. Planta Med 62: 154–159.
  • Rajasekar P, Kaviarasan S, Anuradha CV (2005): l-Carnitine administration prevents oxidative stress in high fructose-fed insulin resistant rats. Diabetologica Croatica 34: 21–28.
  • Shafrir E (2003): Diabetes in animals: Contribution to the understanding of diabetes by study of its etiopathology in animal models, in: Porte D, Sherwin RS, Baron A, ed., Diabetes Mellitus. New York, McGraw-Hill, 231–255.
  • Shimizu S, Ugi S, Maegawa H, Egawa K, Nishio Y, Yoshizaki T, Shi K, Nagai Y, Morino K, Nemoto K (2003): Protein-tyrosine phosphatase 1B as new activator for hepatic lipogenesis via sterol regulatory element-binding protein-1 gene expression. J Biol Chem 278: 43095–43101.
  • Srinivasan K, Patole PS, Kaul CL, Ramarao P (2004): Reversal of glucose intolerance by pioglitazone in high-fat diet fed rats. Methods Find Exp Clin Pharmacol 26: 327–333.
  • Srinivasan K, Viswanad B, Asrat L, Kaul CL, Ramarao P (2005): Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: A model for type 2 diabetes and pharmacological screening. Pharmacol Res 52: 313–320.
  • Taylor SI (1999): Deconstructing type 2 diabetes. Cell 97: 9–12.
  • Veerapur VP, Badiger AM, Joshi SD, Nayak VP, Shastry CS (2004): Antiulcerogenic activity of various extracts of Dodonaea viscosa (L) Jacq. Leaves. Ind J Pharm Sci 66: 407–411.
  • Veerapur VP, Prabhakar KR, Parihar VK, Bansal P, Kandadi MR, Srinivasan KK, Priyadarsini KI, Unnikrishnan MK (2009): Antidiabetic, hypolipidaemic and antioxidant activity of Dodonaea viscosa aerial parts in streptozotocin-induced diabetic rats. J Herb Pharmacother, in press.
  • Vessal M, Hemmati M, Vasei M (2003): Antidiabetic effects of quercetin in streptozocin-induced diabetic rats. Comp Biochem Physiol C Toxicol Pharmacol 135C: 357–364.
  • Zang ZY, Lee SY (2003): PTP-1B inhibitors as potential therapeutics in treatment of type 2 diabetes. Exp Opin Investig Drugs 12: 223–233.
  • Zimmermann GR, Lehár J, Keith CT (2007): Multi-target therapeutics: When the whole is greater than the sum of the parts. Drug Discov Today 12: 34–42.

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