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Research Article

Protective effect of Clerodendron glandulosum extract against experimentally induced metabolic syndrome in rats

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Pages 1312-1319 | Received 07 Aug 2009, Accepted 27 Feb 2010, Published online: 15 Sep 2010

References

  • Ahren B, Pacini G (2004): Importance of quantifying insulin secretion in relation to insulin sensitivity to accurately assess beta cell function in clinical studies. Euro J Endocrinol 150: 97–104.
  • Amos S, Akah PA, Binda L, Enwerem NM, Ogundaini A, Wambebe C, Hussaini IM, Gamaniel KS (2003): Hypotensive activity of the ethanol extract of Pavetta crassipes leaves. Biol Pharm Bull 26: 1674–1680.
  • Ansarullah Thounaojam, M, Jadeja R, Devkar R, Ramachandran AV (2009): Oreocnide integrifolia (Gaud.) Miq. exhibits hypoglycemic and hypolipidemic potentials on streptozotocin diabetic rats: A preliminary dose and duration dependent study. EXCLI J 8: 97–106.
  • Attele AS, Zhou YP, Xie JT, Wu JA, Zhang L, Dey L, Pugh W, Rue PA, Polonsky KS, Yuan CS (2002): Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component. Diabetes 51: 1851–1858.
  • Bakris G, Sowers J, Epstein M, Williams M (2000): Hypertension in patients with diabetes. Why is aggressive treatment essential? Postgrad Med J 107: 53–61.
  • Balaraman R, Dangwal S, Mohan M (2006): Antihypertensive effect of Trigonella foenum-greacum seeds in experimentally induced hypertension in rats. Pharm Biol 44: 568–575.
  • Basciano H, Federico L, Adeli K (2005): Fructose, insulin resistance, and metabolic dyslipidemia. Nutrition & Metabolism 2: 5.
  • Calixto JB (2000): Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents). Braz J Med Biol Res 33:179–189.
  • Catena C, Giacchetti G, Novello M, Colussi G, Cavarape A, Sechi LA (2003): Cellular mechanisms of insulin resistance in rats with fructose-induced hypertension. Am J Hypertens: 16: 973–978.
  • Cox KL, Burke V, Morton AR, Beilin LJ, Puddey IB (2004): Independent and additive effects of energy restriction and exercise on glucose and insulin concentrations in sedentary overweight men. Am J Clin Nutr 80: 308–316.
  • Cummings LE (1988): Commercial foodservice considerations in providing consumer-driven nutrition program elements. Part I. Consumer health objectives and associated employee education needs. Catering & Health 1: 51–71.
  • Dai S, McNeill JH (1995): Fructose-induced hypertension in rats is concentration- and duration-dependent. J Pharmacol Toxicol Meth 33: 101–107.
  • Deb S, Arunachalam A, Das AK (2009): Indigenous knowledge of Nyishi tribes on traditional agroforestry systems. Indian J Trad Knowledge 8: 41–46.
  • Duncan MH, Singh BM, Wise PH, Carter G, Alaghband-Zadeh J (1995): A simple measure of insulin resistance. Lancet 346: 120–121.
  • Dunstan DW, Zimmet PZ, Welborn TA, De Courten MP, Cameron AJ, Sicree RA, Dwyer T, Colagiuri S, Jolley D, Knuiman M, Atkins R, Shaw JE (2002): The rising prevalence of diabetes and impaired glucose tolerance. The Australian Diabetes, Obesity and Lifestyle Study. Diabetes Care 25: 829–834.
  • Edwards KL, Talmud PJ, Newman B, Krauss RM, Austin MA (2001): Lipoprotein candidate genes for multivariate factors of the insulin resistance syndrome: A sib-pair linkage analysis in women twins. Twin Res 4: 41–47.
  • Fineberg SE (1999): The treatment of hypertension and dyslipidemia in diabetes mellitus. Prim Care 26: 951–964.
  • Friedewald WT, Levy RI, Fredrickson DS (1972): Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18: 499–502.
  • Granberry MC, Hawkins JB, Franks AM (2007): Thiazolidinediones in patients with type 2 diabetes mellitus and heart failure. Am J Health Syst Pharm 64: 931–936.
  • Grundy SM, Brewer Jr HB, Cleeman JI, Smith Jr SC (2004): Definition of metabolic syndrome report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition. Circulation 109: 433–438.
  • Grundy SM (2006): Atherogenic dyslipidemia associated with metabolic syndrome and insulin resistance. Clinical Cornerstone 8: 21–27.
  • Hwang IS, Ho H, Hoffman BB, Reaven GM (1987): Fructose-induced insulin resistance and hypertension in rats. Hypertension 10: 512–516.
  • IDF (2006): Diabetes atlas, third edition. Brussels, Belgium: International Diabetes Federation.
  • Isomaa B, Almgren P, Tuomi T, Forsén B, Lahti K, Nissén M, Taskinen MR, Groop L (2001): Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 24: 683–689.
  • Itaya K, Ui M (1965): Colorimetric determination of free fatty acids in biological fluids. J Lipid Res 6: 16–20.
  • Jadeja R, Thounaojam M, Ansarullah Ramachandran, AV, Devkar R (2009a): Phytochemical constituents and free radical scavenging activity of Clerodendron glandulosum Coleb methanolic extract. J Compl Integr Med 1: 19.
  • Jadeja RN, Thounaojam MC, Ansarullah Devkar, RV, Ramachandran AV (2009b): A preliminary study on hypolipidemic effect of aqueous leaf extractof Clerodendron glandulosum Coleb. Int J Green Pharm 3: 285–289.
  • Kala CP (2005): Ethnomedicinal botany of the Apatani in the eastern Himalayan region of India. J Ethnobiol Ethnomed 1: 11.
  • Karpe F, Tan GD (2005): Adipose tissue functions in the insulin-resistance syndrome. Biochem Soc Trans 33: 1045–1048.
  • Le KA, Tappy L (2006): Metabolic effects of fructose. Curr Opin Clin Nutr Metab Care 9: 469–475.
  • Liou SS, Liu IM, Hsu JH, Wu YC, Hsu SF, Chen JT (2002): Release of acetylcholine by Die-Huang-Wan to enhance insulin secretion for lowering plasma glucose in Wistar rats. Auton Neurosci 100: 21–26.
  • Mayes GL, Allan G, Azhar S (2004): High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation. Endocrinology 145: 548–555.
  • Mayes PA (1993): Intermediary metabolism of fructose. Am J Clin Nutr 58:754–765.
  • Ramin A, Willliam J, Pisit P (1996): Antiobesity effect of diazoxide in obese Zucker rats. Metabolism 45: 334–341.
  • Reaven GM (1988): Role of insulin resistance in human disease. Diabetes 37: 1595–1607.
  • Rosen P, Ohly P, Gleichmann H (1997): Experimental benefit of moxonidine on glucose metabolism and insulin secretion in the fructose-fed rat. J Hypertens 15: 31–38.
  • Stern M, Williams K, Gonzalez-Villalpando C (2004): Does the metabolic syndrome improve identification of individuals at risk of type 2 diabetes and/or cardiovascular disease? Diabetes Care 27: 2676–2681.
  • Thounaojam M, Jadeja R, Ansarullah Devkar, R, Ramachandran AV (2009): Dysregulation of lipid and cholesterol metabolism in high fat diet fed hyperlipidemic rats: Protective effect of Sida rhomboidea Roxb leaf extract. J Health Sci 55: 413–420.
  • Valiathian MS (1998): Healing plants. Cur Sci 75: 1122–1126.
  • WHO (2002): Launches the first global strategy on traditional and alternative medicine. WHO press release 38, p. 2. Geneva, World Health Organization.
  • Willett WC (2002): Dietary fat plays a major role in obesity. Obesity Reviews 3: 59–68.
  • Yokozawa T, Kim HJ, Yamabe N, Okamoto T, Cho EJ (2007): The protective role of Kangen-karyu against fructose-induced metabolic syndrome in a rat model. J Pharm Pharmacol 59: 1271–1278.
  • Zammit VA, Waterman IJ, Topping D, McKay G (2001): Insulin stimulation of hepatic triacylglycerol secretion and the etiology of insulin resistance. J Nutr 131: 2074–2077.
  • Zavaroni I, Chen YD, Reaven GM (1982): Studies of the mechanism of fructose-induced hypertriglyceridemia in the rat. Metabolism 31: 1077–1083.

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