References
- Chen AY, Chou R, Shih SJ, Lau D, Gandara D (2004): Enhancement of radiotherapy with DNA topoisomerase 1-targeted drugs. Crit Rev Oncol Hematol 50: 111–119.
- Ferguson LR (1994): Antimutagens as cancer chemopreventive agents in the diet. Mutat Res 307: 395–410.
- Ganguly A, Das B, Roy A, Sen N, Dasgupta SB, Mukhopadhayay S, Majumder HK (2007): Betulinic acid, a catalytic inhibitor of topoisomerase 1, inhibits reactive oxygen species-mediated apoptotic topoisomerase 1-DNA cleavable complex formation in prostate cancer cells but does not affect the process of cell death. Cancer Res 67: 11848–11858.
- Goodsell DS (2002): The molecular perspective: DNA topoisomerases. Oncologist 7: 381–382.
- Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ (1993): Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75: 241–251.
- Hong WK, Lippman SM, Itri LM, Karp DD, Lee JS, Byers RM, Schantz SP, Kramer AM, Lotan R, Peters LJ (1990): Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck. N Eng J Med 323: 795–801.
- Hsu JD, Chou FP, Lee MJ, Chiang HC, Lin YL, Shiow SJ, Wang CJ (1999): Suppression of the TPA-induced expression of nuclear-protooncogenes in mouse epidermis by crocetin via antioxidant activity. Anticancer Res 19: 4221–4227.
- Juang SH, Pan WY, Kuo CC, Liou JP, Hung YM, Chen LT, Hsieh HP, Chang JY (2004): A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells. Biochem Pharmacol 68: 293–303.
- Kaufmann SH (1998): Cell death induced by topoisomerase-targeted drugs: More questions than answers. Biochim Biophys Acta 1400: 195–211.
- Lee IA, Lee JH, Baek NI, Kim DH (2005): Antihyperlipidemic effect of crocin isolated from the fructus of Gardenia jasminoides and its metabolite Crocetin. Biol Pharm Bull 28: 2106–2110.
- Lee SJ, Oh PS, Lim KT (2006): Hepatoprotective and hypolipidaemic effects of glycoprotein isolated from Gardenia jasminoides in mice. Clin Exp Pharmacol Physiol 33: 925–933.
- Machida K, Oyama K, Ishii M, Kakuda R, Yaoita Y, Kikuchi M (2000): Studies of the constituents of Gardenia species. II. Terpenoids from Gardeniae fructus. Chem Pharm Bull (Tokyo) 48: 746–748.
- Mathews-Roth MM (1982): Effect of crocetin on experimental skin tumors in hairless mice. Oncology 39: 362–364.
- Mosmann T (1983): Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55–63.
- Myers JN, Greenberg JS, Mo V, Roberts D (2001): Extracapsular spread. A significant predictor of treatment failure in patients with squamous cell carcinoma of the tongue. Cancer 92: 3030–3036.
- Nguyen DM, Hussain M (2007): The role of the mitochondria in mediating cytotoxicity of anti-cancer therapies. J Bioenerg Biomembr 39: 13–21.
- Ozaki A, Kitano M, Furusawa N, Yamaguchi H, Kuroda K, Endo G (2002): Genotoxicity of Gardenia yellow and its components. Food Chem Toxicol 40: 1603–1610.
- Park EH, Joo MH, Kim SH, Lim CJ (2003): Antiangiogenic activity of Gardenia jasminoides fruit. Phytother Res 17: 961–962.
- Peng CH, Huang CN, Wang CJ (2005): The anti-tumor effect and mechanisms of action of penta-acetyl geniposide. Curr Cancer Drug Targets 5: 299–305.
- Ratan RR, Murphy TH, Baraban JM (1994): Oxidative stress induces apoptosis in embryonic cortical neurons. J Neurochem 62: 376–379.
- Sandur SK, Pandey MK, Sung B, Ahn KS, Murakami A, Sethi G, Limtrakul P, Badmaev V, Aggarwal BB (2007): Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. Carcinogenesis 28: 1765–1773.
- Shimizu T, Pommier Y (1997): Camptothecin-induced apoptosis in p53-null human leukemia HL60 cells and their isolated nuclei: Effects of the protease inhibitors Z-VAD-fmk and dichloroisocoumarin suggest an involvement of both caspases and serine proteases. Leukemia 11: 1238–1244.
- Stavric B (1994): Role of chemopreventers in human diet. Clin Biochem 27: 319–332.
- Stravopodis DJ, Karkoulis PK, Konstantakou EG, Melachroinou S, Lampidonis AD, Anastasiou D, Kachrilas S, Messini-Nikolaki N, Papassideri IS, Aravantinos G, Margaritis LH, Voutsinas GE (2009): Grade-dependent effects on cell cycle progression and apoptosis in response to doxorubicin in human bladder cancer cell lines. Int J Oncol 34: 137–160.
- Tahir SK, Han EK, Credo B, Jae HS, Pietenpol JA, Scatena CD, Wu-Wong JR, Frost D, Sham H, Rosenberg SH, Ng SC (2001): A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors. Cancer Res 61: 5480–5485.
- Tseng TH, Chu CY, Huang JM, Shiow SJ, Wang CJ (1995): Crocetin protects against oxidative damage in rat primary hepatocytes. Cancer Lett 97: 61–67.