5,087
Views
79
CrossRef citations to date
0
Altmetric
Research Article

Antioxidant capacity of hesperidin from Citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines

&
Pages 276-282 | Received 20 Jan 2010, Accepted 15 Jul 2010, Published online: 16 Feb 2011

References

  • Amirhosein A, Sayel GH, Fashad N, Ebrahim H, Mehran G. (2008). Chemoprotective effects of hespridin against genotoxicity induced by cyclophosphamide in mice. Arch Pharm Res, 31, 794–797.
  • Bae EA, Han MJ, Kim DH. (2000). In vitro inhibitory effect of some flavonoids on rotavirus. Biol Pharm Bull, 23, 1122–1124.
  • Balbaa SI, Hilal SH, Zaki AY. (1976). Medicinal plants constituents, second edition. Egypt: Central Agency for University and School Books.
  • Brand-Williams W, Cuvelier ME, Berest C. (1995). Use of a free radical method to evaluate antioxidant activity. Lebensmittel-Wiss und-Technology, 28, 25–30.
  • Cirico TL, Omaye ST. (2006). Additive or synergetic effects of phenolic compounds on human low density lipoprotein oxidation. Food Chem Toxicol, 44, 510–516.
  • Emim JADS, Oliveira AB, Lapa AJ. (1994). Pharmacological evaluation of the anti-inflammatory activity of a citrus bioflavonoid, hesperidin and the isoflavonoids duartin and claussequinone, in rats and mice. J Pharm Pharmacol, 46, 118–122.
  • Etcheverry SB, Ferrer EG, Naso L, Rivadeneira J, Salinas V, Williams PAM. (2008). Antioxidant effects of the VO (IV) hesperidin complex and its role in cancer chemopreventive. J Biol Inorg Chem, 13, 435–447.
  • Finotti E, Majo D. (2003). Influence of solvents on the antioxidant property of flavonoids. Nahran /Food, 47, 168–187.
  • Foti M, Ruberto G. (2001). Kinetic solvent effects on phenolic antioxidants determined by spectrophotometric measurements. J Agric Food Chem, 49, 342–348.
  • Franke AA, Cooney RV, Custer LJ, Mordan LJ, Tanaka Y. (1998). Inhibition of neoplastic transformation and bioavailability of dietary flavonoid agents. Adv Exp Med Biol, 439, 237–248.
  • Gardner PT, White TA, McPhail DB, Duthie GG. (2000). The relative contribution of vitamin C, carotenoids and phenolics to the antioxidant potential of fruit juices. Food Chem, 68, 471–474.
  • Garg A, Garg S, Zaneveld LJD, Singla AK. (2001). Chemistry and pharmacology of the citrus bioflavonoid hesperidin. Phytother Res, 15, 655–609.
  • Gil MI, Tomas-Barberan FA, Hess-Pierce B, Holcroft DM, Kader AA. (2000). Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agric Food Chem, 48, 4581–4589.
  • Kim DH, Song MJ, Bae EA. (2000). Inhibitory effect of herbal medicines on rotavirus infectivity. Biol Pharm Bull, 23, 2183–2188.
  • Kim J, Jung K, Choi J, Chung H. (2004). Hesperetin: A potent antioxidant against peroxynitrite. Free Radic Res, 38, 761–769.
  • Korthuis RJ, Gute DC. (1999). Adhesion molecule expression in post ischemic microvascular dysfunction: activity of a micronised purified flavonoid fraction. J Vasc Res, 36, 15–23.
  • Koyuncu H, Berkarda B, Baykut F, Soybir G, Alati C, Gul H, Altun M. (1999). Preventive effect of hesperidin against inflammation in CD-1 mouse skin caused by tumor promoter. Anticancer Res, 19, 3237–3241.
  • Lee J, Kang Y, Kang J. (2002). Free radical scavenging of flavonoids and their effects on erythrocyte naleak, platelet aggregation and TBARS production. Nutr Sci, 5, 197–202.
  • Lin HC, Chin YG. (2006). Induction of cell apoptosis in 3T3-L1 pre-adipocytes by flavonoids is associated with their antioxidant activity. Molecular Nutr Food Res, 50, 1072–1079.
  • Mabry TJ, Markham KR, Thomas MB. (1970). The systematic identification of flavonoids. New York, USA: Springer Verlag.
  • Manthey JA, Grohman K. (1996). Flavonoids in citrus processing byproducts. J Agric Food Chem, 44, 811–814.
  • McKay DL, Blumberg JB. (2007). A review of the bioactivity of South African herbal teas, (Aspalarhus linearis) and honey bush (Cyclopia intermedia). Phytother Res, 21, 1–16.
  • Monforte MT, Trovato A, Kirjavainen S, Forestieri AM, Lo-Curto RB. (1995). Biological effects of hesperidin, a citrus flavonoid, part 2: Hypolipidemic activity on experimental hypercholesterolemia in the rat. Farmaco, 50, 595–599.
  • Nilsson S, Persson O. (1977). Fungi of Northern Europe 1: Larger fungi (excluding gill fungi). Penguin Books.
  • Palma S, D’Aquino S, Agabbio M, Schirru S. (2005). Changes in flavonoids, ascorbic acid, polyphenol content and antioxidant activity in cold-stored fortune mandarin. Acta Horti, 682, 617–622.
  • Park H, Kim M, Ha E, Chung J. (2003). Apoptotic effect of hesperidin through caspase3 activation in human colon cancer cells SUN-C4. Phytomedicine, 15, 147–151.
  • Pedrielli P, Peduli GF, Skibsted LH. (2001). Antioxidant mechanism of flavonoids, solvent effect on rate constant for chain-breaking reaction of quercetin and epicatechin in autoxidation of methyl linoleate. J Agric Food Chem, 49, 3034–3040.
  • Skehan P, Storen R, Scudiero D, Monks A, McMahon J, Vistic D, Warren JT, Boekesch H, Kenney S, Boyd MR. (1990). New colorimetric cytotoxic assay for anticancer-drug screening. J Natl Cancer Inst, 82, 1107–1112.
  • Tanaka T, Makita H, Kawabata K, Mori H, Kakumoto M. (1997b). Modulation of N-methyl-N-amylnitrosamine induced tumorigenesis by dietary feeding of diosomin and hesperidin, alone and in combination. Cacinogenesis, 18, 761–769.
  • Tanaka T, Makita H, Kawabata K, Mori H. (1997a). Chemoprevention of azoxymethane-induced rat colon carcinogenesis by the naturally occurring flavonoids, diosmin and hesperdin. Carcinogenesis, 18, 957–965.
  • Timoshin AA, Dorkina EG, Paukova EO, Vanin AF. (2005). Quercetin and hesperidin decrease the formation of nitric oxide radicals in rat liver and heart under the conditions of hepatosis. Biofizika, 50, 1145–1149.
  • Venugopal P, Menona AB. (2007). Effect of hespridin on matrix metalloproteinases and antioxidant status during nicotine-induced toxicity. J Toxcol, 238, 90–980
  • Wang H, Cao G, Prior RL. (1996). Total antioxidant capacity of fruits. J Agric Food Chem, 4, 701–7405.
  • Yao YJ, Spooner BM. (1995). Notes on British taxa referred to Aleuria. Mycological Res, 99, 1515–1518.
  • Yoo K, Lee K, Park J, Lee H, Hwang I. (2004). Variation in major antioxidant and total antioxidant activity of yuzu (Citrus junos Sieb ex Tanaka) during maturation and between cultivars. J Agric & Food Chem, 52, 5907–5913.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.