1,478
Views
14
CrossRef citations to date
0
Altmetric
Research Article

Antidiabetic potential of triterpenoid saponin isolated from Primula denticulate

, , , , , & show all
Pages 750-755 | Received 11 Jun 2013, Accepted 17 Nov 2013, Published online: 12 Mar 2014

References

  • Ahmad VU, Saqib QN, Usmanghani K, Pridentigenin E. (1980). A triterpenoid sapogenin from Primula denticulate. Phytochemistry 19:1875–6
  • Ahmad VU, Sultana V, Arif S, Saqib QN. (1988). Saponins from Primula denticulate. Phytochemistry 27:304–6
  • Ahmad VU, Sultana V, Saqib QN. (1990). Triterpenoid saponins from Primula denticulate. Planta Med 56:94–7
  • Anderberg AA, El-Ghazaly G. (2000). Pollen morphology in Primula sect. Carolinella (Primulaceae) and its taxonomic implications. Nord J Bot 20:5–14
  • Bhat JA, Kumar M, Bussmann RW. (2013). Ecological status and traditional knowledge of medicinal plants in Kedarnath Wild life Sanctuary of Garhwal Himalaya, India. J Ethnobiol Ethnomed 9:1
  • Chattopadhyay S, Ramanathan M, Das J, Bhattacharya SK. (1997). Animal model in experimental diabetes mellitus. Indian J Exp Biol 35:1141–5
  • de Melo CL, Queiroz MGR, Fonseca SGC, et al. (2010). Oleanolic acid, a natural triterpenoid improves blood glucose tolerance in normal mice and ameliorates visceral obesity in mice fed a high-fat diet. Chem Biol Interact 185:59–65
  • Evans WC. (2009). Pharmacognosy. 16th ed. New Delhi: ELBS Publication, 138–8
  • Gandhi GR, Sasikumar P. (2012). Antidiabetic effect of Merremia emarginata Burm. F. in streptozotocin induced diabetic rats. Asian Pac J Trop Biomed 2:281–6
  • Gang H, Chi-Ming H, Naam-Sook L. (2002). Circumscriptions and phylogenetic relationships of Primula sects. Augantus and Ranunculoides: Evidence from nrDNA ITS sequences. Acta Bot Sin 44:72–5
  • Gaur R, Raiwani S. (1995). A preliminary report on the threatened arborescent taxa of Garhwal Himalaya. J Indian Bot Soc 74:283–92
  • Jones E, Hughes RE. (1983). Foliar ascorbic acid in some angiosperms. Phytochemistry 22:2493–9
  • Kannan VR, Rajashekhar GS, Rajesh P, et al. (2012). Anti-diabetic activity on ethanol extracts of fruits of Terminalia chebula Retz. Alloxan induced diabetic rats. Am J Drug Disc Dev 2:135–42
  • Kazmi I, Rahman M, Afzal M, et al. (2012). Anti-diabetic potential of ursolic acid stearoyl glucoside: A new triterpenic gycosidic ester from Lantana camara. Fitoterapia 83:142–6
  • Kelso S. (1991). Taxonomy and phytogeography of Primula sect. Cuneifolia in North America. Madrano 38:37–44
  • Matsuda H, Li Y, Yamahara J, Yoshikawa M. (1999). Inhibition of gastric emptying by triterpene saponin, momordin Ic, in mice: Roles of blood glucose, capsaicin-sensitive sensory nerves, and central nervous system. J Pharmacol Exp Therap 289:729–34
  • OECD. (2011). OECD Guideline for Testing of Chemical (420). Adopted 17 December 2001
  • Petit PR, Sauvaire Y, Ponsin G, et al. (1993). Effects of a fenugreek seed extract on feeding behaviour in the rat: Metabolic-endocrine correlates. Pharmacol Biochem Behav 45:369–74
  • Ramirez-Espinosa JJ, Rios MY, Lopez-Martinez S, et al. (2011). Anti-diabetic activity of some pentacyclic acid triterpenoids, role of PTP-1B: In vitro, in silico, and in vivo approaches. Eur J Med Chem 46:2243–51
  • Richards AJ. (2003). Primula, revised edition. Portland: Timber Press
  • Sarabu R, Tilley J. (2005). Recent advances in therapeutic approaches to type 2 diabetes. In: Doherty AM, ed. Annual Reports in Medicinal Chemistry. Vol. 40. Elsevier: Academic Press, 167–81
  • Sridhar M, Thirupathi K, Chaitanya G, et al. (2011). Antidiabetic effect of leaves of Muntingia calabura L., in normal and alloxan-induced diabetic rats. Pharmacologyonline 2:626–32
  • Tokalov SV, Kind B, Wollenweber E, Gutzeit HO. (2004). Biological effects of epicuticular flavonoids from Primula denticulate on human leukemia cells. J Agric Food Chem 52:239–45
  • Vogel GH. (2002). Drug Discovery and Evaluation: Pharmacological Assay, 2nd ed., Berlin, Heidelberg, New York: Springer-Verlag, 947–51
  • Woldemichael GM, Wink MA. (2001). Identification and biological activities of triterpenoid saponins from Chenopodium quinoa. Agric Food Chem 49:2327–32
  • Wollenweber E, Iinuma M, Tanaka T, Mizuno M. (1990). 5-Hydroxy-6,2′-dimethoxyflavone from Primula denticulate. Phytochemistry 29:633–7
  • Yan HF, He CH, Peng C, et al. (2010). Circumscription of Primula subgenus auganthus (Primulaceae) based on chloroplast DNA sequences. J Syst Evol 48:123–32

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.