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Research Article

Bioavailability of caffeic acid in rats and its absorption properties in the Caco-2 cell model

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Pages 1150-1157 | Received 04 Jun 2013, Accepted 30 Dec 2013, Published online: 17 Mar 2014

References

  • Azuma K, Ippoushi K, Nakayama M, et al. (2000). Absorption of chlorogenic acid and caffeic acid in rats after oral administration. J Agric Food Chem 48:5496–500
  • Cartea ME, Franciso M, Soengas P, Velasco P. (2011). Phenolic compounds in Brassica vegetables. Molecules 16:251–80
  • D’Archivio M, Filesi C, Di Benedetto R, et al. (2007). Polyphenols, dietary sources and bioavailability. Ann Ist Super Sanita 43:348–61
  • EI-Seedi HR, EI-Said AMA, Khalifa SA, et al. (2012). Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids. J Agric Food Chem 60:10877–95
  • Fernandez MA, Garcia MD, Saenz MT. (1996). Antibacterial activity of the phenolic acids fractions of Scrophularia frutescens and Scrophularia sambucifolia. J Ethnopharmacol 53:11–14
  • Jaqanathan SK. (2012). Growth inhibition by caffeic acid, one of the phenolic constituents of honey, in HCT 15 colon cancer cells. Sci World J 2012:1–8
  • Kang NJ, Lee KW, Shin BJ, et al. (2009). Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression. Carcinogenesis 30:321–30
  • Larsson SC, Wolk A. (2007). Coffee consumption and risk of liver cancer: A meta-analysis. Gastroenterology 132:1740–5
  • Liu F, Xiao DH. (2011). Compound caffeic acid tablet combined with prednisone and azathioprine in the treatment of chronic refractory refractory idiopathic thrombocytoprnic purpura: A clinical observation. J Huaihai Med 29:377–8
  • Manach C, Scalbert A, Morand C, et al. (2004). Polyphenols: Food sources and bioavailability. Am J Clin Nutr 79:727–47
  • Manach C, Williamson G, Morand C, et al. (2005). Bioavailability and bioefficacy of polphenols in humans. I. Review of 97 bioavailabity studies. Am J Nutr 81:230–42S
  • Mo LL, Wang SJ, Yang BK. (2012). Permeability of ferulic acid in Caco-2 cell model and its absorption properties in rats in vivo. Chin Trad Herbal Drugs 43:947–51
  • Pang KS, Cherry WF, Ulm EH. (1985). Disposition of enalapril in the perfused rat intestine-live preparation: Absorption, metabolism and first-pass effect. J Pharmacol Exp Ther 233:788–95
  • Perrercorn MA, Goldman P. (1972). Caffeic acid metabolism by gnotobiotic rats and their intestinal bacteria. Proc Natl Acad Sci USA 69:1413–15
  • Uang YS, Hsu KY. (1997). A dose-dependent pharmacokinetic study on caffeic acid in rabbits after intravenous administration. Biopharm Drug Dispos 18:727–36
  • Wang SJ, Mo LL, Yang BK, et al. (2012). Optimization of in situ perfused rat intestine-live model. Chin J Clin Pharmacol Ther 17:361–6
  • Yang BK, Wang SJ, Mo LL, et al. (2013). Studies on the absolute bioavailability of cinnamic acid in rats and its absorption properties. Pharm J Chin PLA 29:185–8
  • Yee S. (1997). In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man-fact or myth. Pharm Res 14:763–6
  • Zhang R, Zeng Q, Deng Y, et al. (2013). Phenolic profiles and antioxidant activity of litchi pulp of different cultivars cultivated in Southern China. Food Chem 136:1169–76

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