Vitamin E: A potential therapy for gastric mucosal injury

References

• Ainsah O, Nabishah BM, Osman CB, Khalid BAK. (2000). Naloxone but not glycyrrhizic acid modify stress induced changes in brain serotonin levels. Asia Pac J Pharmacol 14:1–7
   Google Scholar
• al-Moutairy AR, Tariq M. (1996). Effect of vitamin E and selenium on hypothermic restraint stress and chemically-induced ulcers. Dig Dis Sci 41:1165–71
   PubMed Web of Science ®Google Scholar
• Baburao Jain A, Anand Jain V. (2012). Vitamin E, its beneficial role in diabetes mellitus (DM) and its complications. J Clin Diagn Res 6:1624–8
   PubMedGoogle Scholar
• Bardhan J, Chakraborty R, Raychaudburi U. (2011). The 21st century form of vitamin E – Tocotrienol. Curr Pharm Des 17: 2196–205
   PubMed Web of Science ®Google Scholar
• Behery FA, Akl MR, Ananthula S, et al. (2013). Optimization of tocotrienols as antiproliferative and antimigratory leads. Eur J Med Chem 59:329–41
   PubMed Web of Science ®Google Scholar
• Brzozowski T, Konturek PC, Sliwowski Z, et al. (2008). Gastroprotective action of orexin-A against stress-induced gastric damage is mediated by endogenous prostaglandins, sensory afferent neuropeptides and nitric oxide. Regul Pept 148:6–20
   PubMedGoogle Scholar
• Brzozowski T, Konturek PC, Konturek SJ, et al. (1999). Role of prostaglandins generated by cyclooxygenase-1 and cyclooxygenase-2 in healing of ischemia–reperfusion-induced gastric lesions. Eur J Pharmacol 385:47–61
   PubMed Web of Science ®Google Scholar
• Castro GA, Carvalho JE, Tinti SV, et al. (2010). Anti-ulcerogenic effect of a whey protein isolate and collagen hydrolysates against ethanol ulcerative lesions on oral administration to rats. J Med Food 13:83–90
   PubMed Web of Science ®Google Scholar
• Catalán U, Fernández-Castillejo S, Pons L, et al. (2012). alpha-Tocopherol and BAY 11-7082 reduce vascular cell adhesion molecule in human aortic endothelial cells. J Vasc Res 49:319–28
   PubMed Web of Science ®Google Scholar
• Charmandari E, Tsigos C, Chrousos G. (2005). Endrocrinology of the stress response. Ann Rev Physiol 67:259–84
   PubMed Web of Science ®Google Scholar
• Cohn CA, Borda MJ, Schoonen MA. (2004). RNA decomposition by pyrite-induced radicals and possible role of lipids during the emergence of life. Earth Planet Sci Lett 225:271–8
   Web of Science ®Google Scholar
• Cuevas VM, Calzado YR, Guerra YP, et al. (2011). Effects of grape seed extract, vitamin C, and vitamin E on ethanol- and aspirin-induced ulcers. Adv Pharmacol Sci 2011:740687 (1–6)
   Google Scholar
• D'Adamo E, Marcovecchio ML, Giannini C, et al. (2013). Improved oxidative stress and cardio-metabolic status in obese prepubertal children with liver steatosis treated with lifestyle combined with vitamin E. Free Radic Res 47:146–53
   PubMed Web of Science ®Google Scholar
• Fesharaki M, Nasimi A, Mokhtari S, et al. (2006). Reactive oxygen metabolites and anti-oxidative defenses in aspirin-induced gastric damage in rats: Gastroprotection by vitamin E. Pathophysiology 13:237–43
   PubMedGoogle Scholar
• Grabowska AM, Watson SA. (2007). Role of gastrin peptides in carcinogenesis. Cancer Lett 257:1–15
   PubMed Web of Science ®Google Scholar
• Hodul PJ, Dong Y, Husain K, et al. (2013). Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism. PLoS One 8:e52526
   PubMed Web of Science ®Google Scholar
• Ibrahim AAI, Kamisah Y, Nafeeza MI, NurAzlina MF. (2012). The effects of palm vitamin E on stress hormone levels and gastric lesions in stress induced rats. Arch Med Sci 8:22–9
   PubMed Web of Science ®Google Scholar
• Ibrahim AAI, Kamisah Y, Nafeeza MI, NurAzlina MF. (2011). Modulation of gastric motility and gastric lesion formation in stressed rats given enteral supplementation of palm vitamin E and α-tocopherol. Int Med J 18:47–52
   Google Scholar
• Ibrahim IAA, Yusof K, Ismail NM, Mohd Fahami NA. (2008). Protective effect of palm vitamin E and α-tocopherol against gastric lesions induced by water immersion restraint stress in Sprague–Dawley rats. Indian J Pharmacol 42:73–7
   Google Scholar
• Ishihara M, Kojima R, Ito M. (2008). Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol. Eur J Pharmacol 601:143–7
   PubMed Web of Science ®Google Scholar
• Jaarin K, Gapor MT, Nafeeza MI, Fauzee AM. (2002). Effect of various doses of palm vitamin E and tocopherol on aspirin-induced gastric lesions in rats. Int J Exp Pathol 83:295–302
   PubMed Web of Science ®Google Scholar
• Jaarin K, Renuvathani M, Nafeeza MI, Gapor MT. (1999). Comparative effect of palm vitamin E and ranitidine on the healing of ethanol-induced gastric lesions in rats. Int J Exp Pathol 80:259–63
   PubMed Web of Science ®Google Scholar
• Jaarin K, Renuvathani M, Nafeeza MI, Gapor MT. (2000). Effect of palm vitamin E on the healing of ethanol-induced gastric injury in rats. Int J Food Sci Nutr 51:S31–41
   PubMed Web of Science ®Google Scholar
• Jiang Q, Moreland M, Ames BN, Yin X. (2009). A combination of aspirin and gamma-tocopherol is superior to that of aspirin and alpha-tocopherol in anti-inflammatory action and attenuation of aspirin-induced adverse effects. J Nutr Biochem 20:894–900
   PubMed Web of Science ®Google Scholar
• Kamisah Y, Ibrahim AAI, Nafeeza MI, Nur Azlina MF. (2011). Palm tocotrienol rich fraction supplementation suppressed stress-induced gastric oxidative stress in rats. J Appl Pharm Sci 1:118–22
   Google Scholar
• Kamisah Y, MY Norhayati, B Zakri, AY Asmadi. (2009). The effects of palmvitee on δ-aminolevulinic acid-induced hyperbilirubinaemia in suckling rats. Arch Med Sci 5:329–34
   Web of Science ®Google Scholar
• Kim YH, Lee JH, Lee SS, et al. (2002). Long-term stress and Helicobacter pylori infection independently induce gastric mucosal lesions in C57BL/6 mice. Scand J Gastroenterol 37:1259–64
   PubMed Web of Science ®Google Scholar
• Klebanoff SJ. (2005). Myeloperoxidase: Friend and foe. J Leukoc Biol 77:598–625
   PubMed Web of Science ®Google Scholar
• Konturek PC, Brzozowski T, Burnat G, et al. (2010). Gastric ulcer healing and stresslesion preventive properties of pioglitazone are attenuated in diabetic rats. J Physiol Pharmacol 61:429–36
   PubMed Web of Science ®Google Scholar
• Kurose I, Fukumura D, Miura S, et al. (1993). Fluorographic study on the oxidative stress in the process of gastric mucosal injury: Attenuating effect of vitamin E. J Gastroenterol Hepatol 8:254–8
   PubMed Web of Science ®Google Scholar
• Kwichien S, Brzozowski T, Konturek SJ. (2002). Effects of reactive oxygen species action on gastric mucosa in various models of mucosal injury. J Physiol Pharmacol 53:39–50
   PubMed Web of Science ®Google Scholar
• Laloo D, Prasad SK, Krishnamurthy S, Hemalatha S. (2013). Gastroprotective activity of ethanolic root extract of Potentilla fulgens Wall. Ex Hook. J Ethnopharmacol 146:505–14
   PubMed Web of Science ®Google Scholar
• Liu L, Cui J, Song CJ, et al. (2012). H(2)S-releasing aspirin protects against aspirin-induced gastric injury via reducing oxidative stress. PLoS One 7:e46301
   PubMed Web of Science ®Google Scholar
• Mates JM, Christina PG, Ignacio NDC. (1999). Antioxidant enzymes and human diseases. Clin Biochem 32:595–603
   PubMed Web of Science ®Google Scholar
• McCord JM. (1985). Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med 312:159–63
   PubMed Web of Science ®Google Scholar
• Mohd Fahami NA, Ibrahim IA, Kamisah Y, Ismail NM. (2012). Palm vitamin E reduces catecholamines, xanthine oxidase activity and gastric lesions in rats exposed to water-immersion restraint stress. BMC Gastroenterol 12:54
   PubMed Web of Science ®Google Scholar
• Nafeeza MI, Fauzee AM, Kamsiah J, Gapor MT. (2002). Comparative effects of a tocotrienol-rich fraction and tocopherol in aspirin-induced gastric lesions in rats. Asia Pac J Clin Nutr 11:309–13
   PubMed Web of Science ®Google Scholar
• Nafeeza MI, Kang TT. (2005). Synergistic effects of tocopherol, tocotrienol, and ubiquinone in indomethacin-induced experimental gastric lesions. Int J Vitam Nutr Res 75:149–55
   PubMed Web of Science ®Google Scholar
• Norsidah KZ, Yasmadi A, Azizi A, et al. (2013). Palm tocotrienol-rich fraction improves vascular proatherosclerotic changes in hyperhomocysteinemic rats. Evid Based Complement Altern Med 2013:976967 (1–10)
   Web of Science ®Google Scholar
• Nur Azlina MF, Kamisah Y, Chua KH, Qodriyah HMS. (2013). Tocotrienol attenuates stress-induced gastric lesions via activation of prostaglandin and upregulation of COX-1 mRNA. Evid Based Complement Altern Med 2013:804796 (1–8)
   Web of Science ®Google Scholar
• Nur Azlina MF, Nafeeza MI. (2008). Tocotrienol and a-tocopherol reduce corticosterone and noradrenalin levels in rats exposed to restraint stress. Pharmazie 63: 890–2
   PubMed Web of Science ®Google Scholar
• Nur Azlina MF, Rubaizah K, Siti Muliana M, Nafeeza MI. (2009). Modulation of restraint induced gastric oxidative changes in rats by tocotrienol and tocopherol. Int J Pharmacol 5:58–64
   Google Scholar
• Nur Azlina MF, Nafeeza MI, Khalid BAK. (2005). A comparison between tocopherol and tocotrienol effects on gastric parameters in rats exposed to stress. Asia Pac J Clin Nutr 14:358–65
   PubMed Web of Science ®Google Scholar
• Odabasoglu F, Halici Z, Cakir A, et al. (2008). Beneficial effects of vegetable oils (corn, oilive and sunflower oils) and α-tocopherol on anti-inflammatory and gastrointestinal profiles of indomethacin in rats. Eur J Pharmacol 591:300–6
   PubMed Web of Science ®Google Scholar
• Oh TY, Yeo M, Han SU, et al. (2005). Synergism of Helicobacter pylori infection and stress on the augmentation of gastric mucosal damage and its prevention with alpha-tocopherol. Free Radic Biol Med 38:1447–57
   PubMed Web of Science ®Google Scholar
• Ohta Y, Kaida S, Chiba S, et al. (2009). Involvement of oxidative stress in increases in the serum levels of various enzymes and components in rats with water-immersion restraint stress. J Clin Biochem Nutr 45:347–54
   PubMed Web of Science ®Google Scholar
• Ohta Y, Kobayashi T, Imai Y, et al. (2006). Effect of oral vitamin E administration on acute gastric mucosal progression in rats treated with compound 48/80, a mast cell degranulator. Biol Pharm Bull 29:675–83
   PubMed Web of Science ®Google Scholar
• Ohta Y, Nishida K. (2003). Protective effect of coadministered superoxide dismutase and catalase against stress-induced gastric mucosal lesions. Clin Exp Pharmacol Physiol 30:545–50
   PubMed Web of Science ®Google Scholar
• Park HA, Kubicki N, Gnyawali S, et al. (2011). Natural vitamin E α-tocotrienol protects against ischemic stroke by induction of multidrug resistance-associated protein 1. Stroke 42:2308–14
   PubMed Web of Science ®Google Scholar
• Parks DA, Granger DN. (1986). Xanthine oxidase: Biochemistry, distribution and physiology. Acta Physiol Scand 548:87–99
   Google Scholar
• Puppo A, Halliwell B. (1988). Formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Is haemoglobin a biological Fenton reagent? Biochem J 249:185–90
   PubMed Web of Science ®Google Scholar
• Qodriyah HMS, Normadiah MK, Gapor MT, Nafeeza MI. (2002). Tocotrienol-rich fraction and its effects on parameters affecting gastric mucosal integrity after a single exposure to indomethacin. Pak J Nutr 1:89–92
   Google Scholar
• Repetto MG, Llesuy SF. (2002). Antioxidant properties of natural compounds used in popular medicine for gastric ulcers. Braz J Med Biol Res 35:523–34
   PubMed Web of Science ®Google Scholar
• Senol A, Isler M, Karahan AG, et al. (2011). Preventive effect of probiotics and α-tocopherol on ethanol-induced gastric mucosal injury in rats. J Med Food 14:173–9
   PubMed Web of Science ®Google Scholar
• Siriussawakul A, Zaky A, Lang JD. (2010). Role of nitric oxide in hepatic ischemia–reperfusion injury. World J Gastroenterol 16:6079–86
   PubMed Web of Science ®Google Scholar
• Sugimoto N, Yoshida N, Nakamura Y, et al. (2006). Influence of vitamin E on gastric mucosal injury induced by Helicobacter pylori infection. Biofactors 28:9–19
   PubMed Web of Science ®Google Scholar
• Suzuki Y, Ishihara M, Segami T, Ito M. (1998). Anti-ulcer effects of antioxidants, quercetin, α-tocoherol, nifedipine and tetracycline in rats. Jpn J Pharmacol 78:435–41
   PubMedGoogle Scholar
• Szabo B, Hedler L, Lichtwald K, Starke K. (1987). ACTH increases noradrenaline release in pithed rabbits with electrically stimulated sympathetic outflow. Eur J Pharmacol 136:391–9
   PubMed Web of Science ®Google Scholar
• Takeuchi K. (2012). Pathogenesis of NSAID-induced gastric damage: Importance of cyclooxygenase inhibition and gastric hypermotility. World J Gastroenterol 18:2147–60
   PubMed Web of Science ®Google Scholar
• Takeuchi K, Ohtsuki H, Okabe S. (1986). Pathogenesis of compound 48/80-induced gastric lesions in rats. Dig Dis Sci 31:392–400
   PubMed Web of Science ®Google Scholar
• Tariq M. (1988). Gastric anti-ulcer and cytoprotective effect of vitamin E in rats. Res Commun Chem Pathol Pharmacol 60:87–96
   PubMedGoogle Scholar
• Tsukimi Y, Okabe S. (2001). Recent advances in gastrointestinal pathophysiology: Role of heat shock protein in mucosal defense and ulcer healing. Biol Pharm Bull 24:1–9
   PubMed Web of Science ®Google Scholar
• Wada K, Kamisaki Y, Kitano M, et al. (1997). Effects of sucralfate on acute gastric mucosal injury and gastric ulcer induced by ischemia–reperfusion in rats. Pharmacology 54:57–63
   PubMed Web of Science ®Google Scholar
• Wong RS, Radhakrishnan AK. (2012). Tocotrienol research: Past into present. Nutr Rev 70:483–90
   PubMed Web of Science ®Google Scholar