1,788
Views
21
CrossRef citations to date
0
Altmetric
Original Article

Effects of a triplex mixture of Peganum harmala, Rhus coriaria, and Urtica dioica aqueous extracts on metabolic and histological parameters in diabetic rats

, , , , , & show all
Pages 1104-1109 | Received 04 May 2014, Accepted 28 Aug 2014, Published online: 23 Jan 2015

References

  • Ahangarpour A, Mohammadian M, Dianat M. (2012). Antidiabetic effect of hydroalcholic Urtica dioica leaf extract in male rats with fructose-induced insulin resistance. Iran J Med Sci 37:181–6
  • Anwer T, Sharma M, Pillai KK, et al. (2012). Antihyperglycemic, antidyslipidemic and antioxidant activity of Rhus coriaria in STZ-induced type 2 diabetic rats. Afr J Pharm Pharmacol 6:2851–5
  • Asghari G, Lockwood GB. (2002). Stereospecific biotransformation of (±) phenylethyl propionate by cell cultures of Peganum harmala L. Iran Biomed J 6:43–6
  • Astulla A, Zaima K, Matsuno Y, et al. (2008). Alkaloids from the seeds of Peganum harmala showing antiplasmodial and vasorelaxant activities. J Nat Med 62:470–2
  • Bnouham M, Merhfour FZ, Ziyyat A, et al. (2003). Antihyperglycemic activity of the aqueous extract of Urtica dioica. Fitoterapia 74:677–81
  • Brunzell JD, Davidson M, Furberg CD, et al. (2008). Lipoprotein management in patients with cardiometabolic risk. J Am Coll Cardiol 51:1512–24
  • Clevenger JF. (1928). Apparatus for the determination of volatile oil. J Am Pharm Assoc 17:345–9
  • Fakir H, Korkmaz M, Güller B. (2009). Medicinal plant diversity of western Mediterranean region in Turkey. J Appl Biol Sci 3:30–40
  • Farzami B, Ahmadvand D, Vardasbi S, et al. (2003). Induction of insulin secretion by a component of Urtica dioica leave extract in perifused islets of Langerhans and its in vivo effects in normal and streptozotocin diabetic rats. J Ethnopharmacol 89:47–53
  • Giancarlo S, Rosa LM, Nadjafi F, Francesco M. (2006). Hypoglycaemic activity of two spices extract: Rhus coriaria L, Bunium persicum Boiss. Nat Prod Res 20:882–6
  • Goel N, Singh N, Saini R. (2009). Efficient in vitro multiplication of Syrian Rue (Peganum harmala L.) using 6-benzylaminopurine pre-conditioned seedling explants. Nat Sci 7:129–34
  • Güneş Hv, Değirmenci İ, Aydin M, et al. (1999). The effects of Rumex patientia L. and Urtica dioica L. on some blood and urine parameters, and liver and kidney histology in diabetic rats. Turk J Med Sci 29:227–32
  • Jakus V. (2000). The role of free radicals, oxidative stress and antioxidant systems in diabetic vascular disease. Bratisl Med J 101:541–51
  • Kavalali G, Tuncel H, Goksel S, Hatemi HH. (2003). Hypoglycemic activity of Urtica pilulifera in streptozotocin-diabetic rats. J Ethnopharmacol 84:241–5
  • Khaki AA, Khaki A, Nouri M, et al. (2009). Evaluation effects of quercetin on liver apoptosis in streptozotocin-induced diabetic rat. J Med Plants 8:70–8
  • Kianbakht S, Khalighi-Sigaroodi F, Dabaghian FH. (2013). Improved glycemic control in patients with advanced type 2 diabetes mellitus taking Urtica dioica leaf extract: A randomized double-blind placebo-controlled clinical trial. Clin Lab 59:1071–6
  • Lamchouri F, Settaf A, Cherrah Y, et al. (2002). Experimental toxicity of Peganum harmala seeds. Ann Pharm Fr 60:123–9
  • Nuraliev IUN, Avezov G.A. (1992). The efficacy of quercetin in alloxan diabetes. Eksp Klin Farmakol 55:42–4
  • Ozkol H, Tuluce Y, Dilsiz N, Koyuncu İ. (2013). Therapeutic potential of some plant extracts used in Turkish traditional medicine on streptozocin-induced type1 diabetes mellitus in rats. J Membr Biol 246:47–55
  • Pashazadeh M, Rezaei A, Pashazadeh M, et al. (2013). Effect of Rhus coriaria consumption on levels of blood glucose and lipids in alloxan-induced diabetic rats. Int J Emerg Trends Pharm Sci 1:34–7
  • Pourahmad J, Eskandari MR, Shakibaei R, Kamalinejad M. (2009). A search for hepatoprotective activity of aqueous extract of Rhus coriaria L. against oxidative stress cytotoxicity. Food Chem Toxicol 48:854–8
  • Rahimi R, Nikfar S, Larijani B, Abollahi M. (2005). A review on the role of antioxidants in the management of diabetes and its complications. Biomed Pharmacother 59:365–73
  • Rayne S, Mazza G. (2007). Biological activities of extracts from sumac (Rhus spp.): A review. Plant Foods Hum Nutr 62:165–75
  • Rehman A, Jenner A, Halliwel B. (2000). Gas chromatography–mass spectrometry analysis of DNA: Optimization of protocols for isolation and analysis of DNA from human blood. Method Enzymol 319:401–17
  • Sayhan MB, Kanter M, Oguz S, Erboga M. (2012). Protective effect of Urtica dioica L. on renal ischemia/reperfusion injury in rat. J Mol Histol 43:691–8
  • Singh AB, Chaturvedi JP, Narender T, Srivastava AK. (2008). Preliminary studies on the hypoglycemic effect of Peganum harmala L. seeds ethanol extract on normal and streptozotocin induced Diabetic Rats. Ind J Clin Biochem 23:391–3
  • Singh AB, Khaliq T, Chaturvedi JP, et al. (2012). Anti-diabetic and anti-oxidative effects of 4-hydroxypipecolic acid in C57BL/KsJ-db/db mice. Hum Exp Toxicol 31:57–65
  • Smith JF. (2003). Antidiabetic drugs. Med Lib 5:5–6
  • Soliman AM, Abu-El-Zahab HS, Alswiai GA. (2012). Efficacy evaluation of the protein isolated from Peganum harmala seeds as an antioxidant in liver of rats. Asia Pac J Trop Med 6:285–95
  • Stanely P, Prince M, Menon VP. (2000). Hypoglycaemic and other related actions of Tinospora cordifolia roots in alloxan-induced diabetic rats. J Ethnopharmacol 70:9–15
  • Suji G, Sivakami S. (2003). Approaches to the treatment of diabetes mellitus: An overview. Cell Mol Biol 49:635–9
  • Tahery H, Mehdi M, Fard MH, et al. (2013). Effects of aqueous and ethanolic extracts of Peganum harmala L seeds on lipids profile in rats. J Birjand Univ Med Sci 20:108–14
  • Tetko IV, Gasteiger J, Todeschini R, et al. (2005). Virtual computational chemistry laboratory – Design and description. J Comput Aided Mol Des 19:453–63
  • Ur-Rahman A, Zaman K. (1989). Medicinal plants with hypoglycemic activity. J Ethnopharmacol 26:1–55
  • Vincet AM, Russell JW, Low P, Feldman EL. (2003). Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr Rev 25:612–28
  • Ziyyat A, Legssyer A, Mekhfi H, et al. (1997). Phythotherapy of hypertension and diabetes in oriental Morocco. J Ethnopharmacol 58:45–54

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.