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Modern Rheumatology Volume 25, 2015 - Issue 1
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Letter

Epstein-Barr virus-related MTX-LPD in rheumatoid arthritis patients exhibits a viral pattern of the CD64 and CD35 expression on neutrophils: Three case reports

Sho MokudaDepartment of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan;Department of Immunology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima City, Japan;Department of Analytical Pathology, Ehime University Graduate School of Medicine, Toon City, JapanCorrespondence[email protected]
,
Tatsuhiko MiyazakiDepartment of Analytical Pathology, Ehime University Graduate School of Medicine, Toon City, Japan
,
Yukari SaekiDepartment of Clinical Laboratory, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan
,
Junya MasumotoDepartment of Analytical Pathology, Ehime University Graduate School of Medicine, Toon City, Japan
,
Masamoto KannoDepartment of Immunology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima City, Japan
&
Kiyoshi TakasugiDepartment of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital, Matsuyama City, Ehime, Japan
Pages 166-168 | Received 04 Dec 2013, Accepted 12 Dec 2013, Published online: 05 Feb 2014

References

  • Harris NL, Swerdlow SH. Methotrexate-associated lymphoproliferative disorders. In: Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. Pathology and genetics, tumours of haematopoietic and lymphoid tissues, World Health Organization classification of tumours. Lyon: IARC Press; 2001. p. 270–1.
  • Salloum E, Cooper DL, Howe G, Lacy J, Tallini G, Crouch J, et al. Spontaneous regression of lymphoproliferative disorders in patients treated with methotrexate for rheumatoid arthritis and other rheumatic diseases. J Clin Oncol. 1996;14(6):1943–9.
  • Mariette X, Cazals-Hatem D, Warszawki J, Liote F, Balandraud N, Sibilia J; Investigators of the Club Rhumatismes et Inflammation. Lymphomas in rheumatoid arthritis patients treated with methotrexate: a 3-year prospective study in France. Blood. 2002;99(11):3909–15.
  • Dawson TM, Starkebaum G, Wood BL, Willkens RF, Gown AM. Epstein-Barr virus, methotrexate, and lymphoma in patients with rheumatoid arthritis and primary Sjögren's syndrome: case series. J Rheumatol. 2001;28(1):47–53.
  • Hoshida Y, Xu JX, Fujita S, Nakamichi I, Ikeda J, Tomita Y, et al. Lymphoproliferative disorders in rheumatoid arthritis: clinicopathological analysis of 76 cases in relation to methotrexate medication. J Rheumatol. 2007;34(2):322–31.
  • Mokuda S, Doi O, Takasugi K. Simultaneous quantitative analysis of the expression of CD64 and CD35 on neutrophils as markers to differentiate between bacterial and viral infections in patients with rheumatoid arthritis. Mod Rheumatol. 2012;22(5):750–7.

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