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ORIGINAL ARTICLE

A novel rat model of hip pain by intra-articular injection of nerve growth factor-characteristics of sensory innervation and inflammatory arthritis

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Pages 931-936 | Received 02 Dec 2014, Accepted 23 Feb 2015, Published online: 02 Apr 2015

References

  • Nakamura J, Kamegaya M, Saisu T, Someya M, Koizumi W, Moriya H. Treatment for developmental dysplasia of the hip using the Pavlik harness: long-term results. J Bone Joint Surg Br. 2007;89(2):230–5.
  • Shigemura T, Ohtori S, Kishida S, Nakamura J, Takeshita M, Takazawa M, et al. Neuropathic pain in patients with osteoarthritis of hip joint. Eur Orthop Traumatol. 2011;2:73–7.
  • Nakamura J, Kishida S, Harada Y, Iida S, Oinuma K, Yamamoto S, et al. Inter-observer and intra-observer reliabilities of the Japanese Ministry of Health, Labor and Welfare type classification system for osteonecrosis of the femoral head. Mod Rheumatol. 2011;21(5):488–94.
  • Ikeuchi K, Hasegawa Y, Seki T, Takegami Y, Amano T, Ishiguro N. Epidemiology of nontraumatic osteonecrosis of the femoral head in Japan. Mod Rheumatol. 2015;25(2):278–81.
  • Takazawa M, Nakamura J, Abe I, Ohtori S, Watanabe A, Sato Y, et al. Predictive factors for acetabular labral lesions in osteoarthritis of the hip with radial magnetic resonance imaging - A cross-sectional study. Mod Rheumatol. 2014;24(6):974–9.
  • Nakamura J, Oinuma K, Ohtori S, Watanabe A, Shigemura T, Sasho T, et al. Distribution of hip pain in osteoarthritis patients secondary to developmental dysplasia of the hip. Mod Rheumatol. 2013;23(1): 119–24.
  • Saito J, Ohtori S, Kishida S, Nakamura J, Takeshita M, Shigemura T, et al. Difficulty of diagnosing the origin of lower leg pain in patients with both lumbar spinal stenosis and hip joint osteoarthritis. Spine (Phila Pa 1976). 2012;37(25):2089–93.
  • Birnbaum K, Prescher A, Hepler S, Heller D. The sensory innervation of the hip: an anatomical study. Surg Radiol Anat. 1997;19:371–5.
  • Nakajima T, Ohtori S, Inoue G, Koshi T, Yamamoto S, Nakamura J, et al. The characteristics of dorsal-root ganglia and sensory innervation of the hip in rats. J Bone Joint Surg Br. 2008;90(2):254–7.
  • Nakajima T, Ohtori S, Yamamoto S, Takahashi K, Harada Y. Differences in innervation and innervated neurons between hip and inguinal skin. Clin Orthop Relat Res. 2008;466(10):2527–32.
  • Miura Y, Ohtori S, Nakajima T, Kishida S, Harada Y, Takahashi K. Dorsal root ganglion neurons with dichotomizing axons projecting to the hip joint and the knee skin in rats: possible mechanism of referred knee pain in hip joint disease. J Orthop Sci. 2011;16(6):799–804.
  • Dirmeier M, Capellino S, Schubert T, Angele P, Anders S, Straub RH. Lower density of synovial nerve fibres positive for calcitonin gene-related peptide relative to substance P in rheumatoid arthritis but not in osteoarthritis. Rheumatology (Oxford). 2008;47(1):36–40.
  • Fukui Y, Ohtori S, Yamashita M, Yamauchi K, Inoue G, Suzuki M, et al. Low affinity NGF receptor (p75 neurotrophin receptor) inhibitory antibody reduces pain behavior and CGRP expression in DRG in the mouse sciatic nerve crush model. J Orthop Res. 2010;28(3): 279–83.
  • Takeshita M, Nakamura J, Ohtori S, Inoue G, Orita S, Miyagi M, et al. Sensory innervation and inflammatory cytokines in hypertrophic synovia associated with pain transmission in osteoarthritis of the hip: a case control study. Rheumatology (Oxford). 2012;51(10):1790–5.
  • Krenn V, Morawietz L, Burmester GR, Kinne RW, Mueller-Ladner U, Muller B, et al. Synovitis score: discrimination between chronic low-grade and high-grade synovitis. Histopathology. 2006;49(4):358–64.
  • Mankin HJ, Dorfman H, Lippiello L, Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am. 1971;53(3):523–37.
  • Ashraf S, Mapp PI, Burston J, Bennett AJ, Chapman V, Walsh DA. Augmented pain behavioural responses to intra-articular injection of nerve growth factor in two animal models of osteoarthritis. Ann Rheum Dis. 2014;73(9):1710–8.
  • Walsh DA, McWilliams DF, Turley MJ, Dixon MR, Fransès RE, Mapp PI, et al. Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis. Rheumatology (Oxford). 2010;49(10):1852–61.
  • Manni L, Lundeberg T, Tirassa P, Aloe L. Role of cholecystokinin-8 in nerve growth factor and nerve growth factor mRNA expression in carrageenan-induced joint inflammation in adult rats. Rheumatology (Oxford). 2002;41(7):787–92.
  • Barthel C, Yeremenko N, Jacobs R, Schmidt RE, Bernateck M, Zeidler H, et al. Nerve growth factor and receptor expression in rheumatoid arthritis and spondyloarthritis. Arthritis Res Ther. 2009;11(3):R82. doi: 10.1186/ar2716.
  • Grills BL, Schuijers JA, Ward AR. Topical application of nerve growth factor improves fracture healing in rats. J Orthop Res. 1997;15(2): 235–42.
  • Manni L, Lundeberg T, Fiorito S, Bonini S, Vigneti E, Aloe L. Nerve growth factor release by human synovial fibroblasts prior to and following exposure to tumor necrosis factor-α, interleukin-1β and cholecystokinin-8: the possible role of NGF in the inflammatory response. Clin Exp Rheumatol. 2003;21(5):617–24.
  • Woolf CJ, Safieh-Garabedian B, Ma QP, Crilly P, Winter J. Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience. 1994;62(2):327–31.
  • Ohtori S, Takahashi K, Moriya H. Calcitonin gene-related peptide immunoreactive DRG neurons innervating the cervical facet joints show phenotypic switch in cervical facet injury in rats. Eur Spine J. 2003;12(2):211–5.
  • Ohtori S, Takahashi K, Chiba T, Yamagata M, Sameda H, Moriya H. Calcitonin gene-related peptide immunoreactive neurons with dichotomizing axons projecting to the lumbar muscle and knee in rats. Eur Spine J. 2003;12(6):576–80.
  • Orita S, Ishikawa T, Miyagi M, Ochiai N, Inoue G, Eguchi Y, et al. Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain. BMC Musculoskelet Disord. 2011;12:134. doi: 10.1186/1471-2474-12-134.
  • Morales TI. The quantitative and functional relation between insulin-like growth factor-I (IGF) and IGF-binding proteins during human osteoarthritis. J Orthop Res. 2008;26(4):465–74.
  • Shirai C, Ohtori S, Kishida S, Harada Y, Moriya H. The pattern of distribution of PGP 9.5 and TNF-alpha immunoreactive sensory nerve fibers in the labrum and synovium of the human hip joint. Neurosci Lett. 2009;450(1):18–22.
  • Lane NE, Schnitzer TJ, Birbara CA, Mokhtarani M, Shelton DL, Smith MD, et al. Tanezumab for the treatment of pain from osteoarthritis of the knee. N Engl J Med. 2010;363(16):1521–31.
  • Brown MT, Murphy FT, Radin DM, Davignon I, Smith MD, West CR. Tanezumab reduces osteoarthritic hip pain: results of a randomized, double-blind, placebo-controlled phase III trial. Arthritis Rheum. 2013;65(7):1795–803.
  • Spierings EL, Fidelholtz J, Wolfram G, Smith MD, Brown MT, West CR. A phase III placebo- and oxycodone-controlled study of tanezumab in adults with osteoarthritis pain of the hip or knee. Pain. 2013;154(9):1603–12.
  • Miyagi M, Ishikawa T, Kamoda H, Suzuki M, Sakuma Y, Orita S, et al. Assessment of pain behavior in a rat model of intervertebral disc injury using the CatWalk gait analysis system. Spine (Phila Pa. 1976). 2013;38(17):1459–65.
  • Yamazaki H, Ochiai N, Kenmoku T, Ohtori S, Sasho T, Miyagi M, et al. Assessment of pain-related behavior and pro-inflammatory cytokine levels in the rat rotator cuff tear model. J Orthop Res. 2014;32(2):286–90.

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