369
Views
10
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Clinical utility of antibiotic-loaded hydroxyapatite block for treatment of intractable periprosthetic joint infection and septic arthritis of the hip

, , , , &
Pages 937-942 | Received 05 Dec 2014, Accepted 04 Mar 2015, Published online: 30 Apr 2015

References

  • Dale H, Fenstad AM, Hallan G, Havelin LI, Furnes O, Overgaard S, et al. Increasing risk of prosthetic joint infection after total hip arthroplasty. Acta Orthop. 2012;83(5):449–58.
  • Insall JN, Thompson FM, Brause BD. Two-stage reimplantation for the salvage of infected total knee arthroplasty. J Bone Joint Surg Am. 1983;65(8):1087–98.
  • Cui Q, Mihalko WM, Shields JS, Ries M, Saleh KJ. Antibiotic-impregnated cement spacers for the treatment of infection associated with total hip or knee arthroplasty. J Bone Joint Surg Am. 2007;89(4): 871–82.
  • Parvizi J, Adeli B, Zmistowski B, Restrepo C, Greenwald AS. Management of periprosthetic joint infection: the current knowledge: AAOS exhibit selection. J Bone Joint Surg Am. 2012;94(14):e104.
  • Senthi S, Munro JT, Pitto RP. Infection in total hip replacement: meta-analysis. Int Orthop. 2011;35(2):253–60.
  • Hsieh PH, Shih CH, Chang YH, Lee MS, Shih HN, Yang WE. Two-stage revision hip arthroplasty for infection: comparison between the interim use of antibiotic-loaded cement beads and a spacer prosthesis. J Bone Joint Surg Am. 2004;86-A(9):1989–97.
  • Persson C, Baleani M, Guandalini L, Tigani D, Viceconti M. Mechanical effects of the use of vancomycin and meropenem in acrylic bone cement. Acta Orthop. 2006;77(4):617–21.
  • Klekamp J, Dawson JM, Haas DW, DeBoer D, Christie M. The use of vancomycin and tobramycin in acrylic bone cement:biomechanical effects and elution kinetics for use in joint arthroplasty. J Arthroplasty. 1999;14(3):339–46.
  • Peng KT, Kuo LT, Hsu WH, Huang TW, Tsai YH. The effect of endoskeleton on antibiotic impregnated cement spacer for treating deep hip infection. BMC Musculoskelet Disord. 2011;12:10.
  • Anagnostakos K, Furst O, Kelm J. Antibiotic-impregnated PMMA hip spacers: current status. Acta Orthop. 2006;77(4):628–37.
  • Harris CM, Kopecka H, Harris TM. Vancomycin: structure and transformation to CDP-1. J Am Chem Soc. 1983;105(23):6915–22.
  • Harris CM, Kopecka H, Harris TM. The stabilization of vancomycin by peptidoglycan analogs. J Antibiot (Tokyo). 1985;38(1):51–7.
  • Somerville AL, Wright DH, Rotschafer JC. Implications of vancomycin degradation products on therapeutic drug monitoring in patients with end-stage renal disease. Pharmacotherapy. 1999;19(6):702–7.
  • Vesga O, Agudelo M, Salazar BE, Rodriguez CA, Zuluaga AF. Generic vancomycin products fail in vivo despite being pharmaceutical equivalents of the innovator. Antimicrob Agents Chemother. 2010;54(8):3271–9.
  • Hiramatsu K. Vancomycin resistance in staphylococci. Drug Resist Updat. 1998;1(2):135–50.
  • Korkusuz F, Uchida A, Shinto Y, Araki N, Inoue K, Ono K. Experimental implant-related osteomyelitis treated by antibiotic-calcium hydroxyapatite ceramic composites. J Bone Joint Surg Br. 1993;75(1):111–4.
  • Shinto Y, Uchida A, Korkusuz F, Araki N, Ono K. Calcium hydroxyapatite ceramic used as a delivery system for antibiotics. J Bone Joint Surg Br. 1992;74(4):600–4.
  • Saito T, Takeuchi R, Hirakawa K, Nagata N, Yoshida T, Koshino T, et al. Slow-releasing potential of vancomycin-loaded porous hydroxyapatite blocks implanted into MRSA osteomyelitis. J Biomed Mater Res. 2002;63(3):245–51.
  • Yamashita Y, Uchida A, Yamakawa T, Shinto Y, Araki N, Kato K. Treatment of chronic osteomyelitis using calcium hydroxyapatite ceramic implants impregnated with antibiotic. Int Orthop. 1998;22(4): 247–51.
  • Kobayashi N, Inaba Y, Choe H, Aoki C, Ike H, Ishida T, et al. Simultaneous intraoperative detection of methicillin-resistant Staphylococcus and pan-bacterial infection during revision surgery: use of simple DNA release by ultrasonication and real-time polymerase chain reaction. J Bone Joint Surg Am. 2009;91(12): 2896–902.
  • Kobayashi N, Bauer TW, Sakai H, Togawa D, Lieberman IH, Fujishiro T, Procop GW. The use of newly developed real-time PCR for the rapid identification of bacteria in culture-negative osteomyelitis. Joint Bone Spine. 2006;73(6):745–7.
  • Lonner JH, Desai P, Dicesare PE, Steiner G, Zuckerman JD. The reliability of analysis of intraoperative frozen sections for identifying active infection during revision hip or knee arthroplasty. J Bone Joint Surg Am. 1996;78(10):1553–8.
  • Tsaras G, Maduka-Ezeh A, Inwards CY, Mabry T, Erwin PJ, Murad MH, et al. Utility of intraoperative frozen section histopathology in the diagnosis of periprosthetic joint infection: a systematic review and meta-analysis. J Bone Joint Surg Am. 2012;94(18):1700–11.
  • Quave CL, Plano LR, Pantuso T, Bennett BC. Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence of methicillin-resistant Staphylococcus aureus. J Ethnopharmacol. 2008;118(3):418–28.
  • Wiegand I, Hilpert K, Hancock RE. Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat Protoc. 2008;3(2):163–75.
  • Heise U, Osborn JF, Duwe F. Hydroxyapatite ceramic as a bone substitute. Int Orthop. 1990;14(3):329–38.
  • Lemons JE, Bajpai PK, Patka P, Bonel G, Starling LB, Rosenstiel T, et al. Significance of the porosity and physical chemistry of calcium phosphate ceramics. Orthopedic uses. Ann N Y Acad Sci. 1988;523:278–82.
  • Uchida A, Nade SM, McCartney ER, Ching W. The use of ceramics for bone replacement. A comparative study of three different porous ceramics . J Bone Joint Surg Br. 1984;66(2):269–75.
  • Mortazavi SM, Vegari D, Ho A, Zmistowski B, Parvizi J. Two-stage exchange arthroplasty for infected total knee arthroplasty: predictors of failure. Clin Orthop Relat Res. 2011;469(11):3049–54.
  • Sherrell JC, Fehring TK, Odum S, Hansen E, Zmistowski B, Dennos A, et al. The Chitranjan Ranawat Award: fate of two-stage reimplantation after failed irrigation and debridement for periprosthetic knee infection. Clin Orthop Relat Res. 2011;469(1):18–25.
  • Bejon P, Berendt A, Atkins BL, Green N, Parry H, Masters S, et al. Two-stage revision for prosthetic joint infection: predictors of outcome and the role of reimplantation microbiology. J Antimicrob Chemother. 2010;65(3):569–75.
  • Parvizi J, Azzam K, Ghanem E, Austin MS, Rothman RH. Periprosthetic infection due to resistant staphylococci: serious problems on the horizon. Clin Orthop Relat Res. 2009;467(7):1732–9.
  • Masri BA, Duncan CP, Beauchamp CP. Long-term elution of antibiotics from bone-cement: an in vivo study using the prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) system. J Arthroplasty. 1998;13(3):331–8.
  • Bertazzoni Minelli E, Benini A, Magnan B, Bartolozzi P. Release of gentamicin and vancomycin from temporary human hip spacers in two-stage revision of infected arthroplasty. J Antimicrob Chemother. 2004;53(2):329–34.
  • Anagnostakos K, Wilmes P, Schmitt E, Kelm J. Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivo. Acta Orthop. 2009;80(2):193–7.
  • White LO, Edwards R, Holt HA, Lovering AM, Finch RG, Reeves DS. The in-vitro degradation at 37 degrees C of vancomycin in serum, CAPD fluid and phosphate-buffered saline. J Antimicrob Chemother. 1988;22(5):739–45.
  • Dooley DP, Tyler JR, Wortham WG, Harrison LS, Starnes WF Jr., Collins GR, et al. Prolonged stability of antimicrobial activity in peritoneal dialysis solutions. Perit Dial Int. 2003;23(1):58–62.
  • Nornoo AO, Elwell RJ. Stability of vancomycin in icodextrin peritoneal dialysis solution. Ann Pharmacother. 2006;40(11):1950–4.
  • de Vin F, Rutherford P, Faict D. Intraperitoneal administration of drugs in peritoneal dialysis patients: a review of compatibility and guidance for clinical use. Perit Dial Int. 2009;29(1):5–15.
  • Samuel JR, Gould FK. Prosthetic joint infections: single versus combination therapy. J Antimicrob Chemother. 2010;65(1):18–23.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.