26
Views
1
CrossRef citations to date
0
Altmetric
Research Article

Individual and combined effects of mesenchymal stromal cells and recombinant stimulatory cytokines on the in vitro growth of primitive hematopoietic cells from human umbilical cord blood

, , , , , , & show all
Pages 886-896 | Published online: 10 Nov 2009

References

  • Butler AC, Fitzsimons EJ, Graham GJ. Ex vivo expansion of cord blood cells: the clinical potential. Cohen SBA, Gluckman E, Rubinstein P, Madrigal JA. Cord Blood Characteristics. UK: Martin Dunitz; 2000. p 169–203.
  • Miller CL, Audet J, Eaves CJ. Ex vivo expansion of human and murine hematopoietic stem cells. Klug CA, Jordan CT. Hematopoietic Stem Cell Protocols. USA: Humana Press; 2002. p 189–208.
  • Haylock DN, Nilsson SK. Expansion of umbilical cord blood for clinical transplantation. Curr Stem Cell Res Ther 2007;2:324–35.
  • Douay L. Experimental culture conditions are critical for the ex vivo expansion of hematopoietic cells. J Hematother Stem Cell Res 2001;10:341–6.
  • Piacibello W, Sanavio F, Garetto L, Severino A, Bergandi D, Ferrario J, . Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood. Blood 1997;89:2644–53.
  • Mayani H, Lansdorp PM. Biology of human umbilical cord blood-derived hematopoietic stem/progenitor cells. Stem Cells 1998;16:153–65.
  • Pecora AL. Progress in clinical applications of progenitor cells expanded with hematopoietic growth factors. Curr Opin Hematol 2001;8:142–8.
  • Prince HM, Simmons PJ, Whitty G, Wall D, Barber L, Toner GC, . Improved haematopoietic recovery following transplantation with ex vivo-expanded mobilized blood cells. Br J Haematol 2004;126:536–45.
  • Shpall EJ, Quinones R, Giller R, . Transplantation of ex vivo expanded cord blood cells. Biol Blood Marrow Transplant 2002;8:368–76.
  • Jaroscak J, Goltry K, Smith A, . Augmentation of umbilical cord blood (UCB) transplantation with ex vivo-expanded UCB cells: results of a phase I trial using the Aastrom-Replicell System. Blood 2003;101:5061–7.
  • Mayani H, Guilbert LJ, Janowska-Wieczorek A. Biology of the hemopoietic microenvironment. Eur J Haematol 1992;49:225–33.
  • Charbord P. Microenvironmental cell populations essential for the support of hematopoietic stem cells. Zon LI. Hematopoiesis. USA: Oxford University Press; 2001. 691–701.
  • Scadden DT. The stem cell niche as an entity of action. Nature 2006;441:1075–9.
  • Calvi LM, Adams GB, Weibrecht KW, . Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003;425:836–41.
  • Dazzi F, Ramasamy R, Glennie S, Jones SP, Roberts I. The role of mesenchymal stem cells in haematopoiesis. Blood Rev 2006;20:161–71.
  • McNiece I, Harrington J, Turney J, . Ex vivo expansion of cord blood mononuclear cells on mesenchymal stem cells. Cytotherapy 2004;6:311–17.
  • Rosler E, Brandt J, Chute J, Hoffman R. Cocultivation of umbilical cord blood cells with endothelial cells leads to extensive amplification of competent CD34+ CD38− cells. Exp Hematol 2000;28:841–52.
  • Fei XM, Wu YJ, Chang Z, . Co-culture of cord blood CD34+ cells with human BM mesenchymal stromal cells enhances short-term engraftment of cord blood cells in NOD/SCID mice. Cytotherapy 2007;9:338–47.
  • Hutton JF, Rosenkov V, Khor FSL, D'Andrea RJ, Lewis ID. Bone morphogenetic protein 4 contributes to the maintenance of primitive cord blood hematopoietic progenitors in an ex vivo stroma-noncontact co-culture system. Stem Cells Dev 2006;15:805–13.
  • Ando K, Nakamura Y, Chargui J, . Extensive generation of human cord blood CD34+ stem cells from Lin− CD34− cells in a long-term in vitro system. Exp Hematol 2000;28:690–9.
  • Magin AS, Korfer N, Partenheimer H, Lange C, Zander A, Noll T. Primary cells as feeder cells for coculture expansion of human hematopoietic stem cells from umbilical cord blood: a comparative study. Stem Cells Dev 2009;18:173–86.
  • Flores-Guzman P, Flores-Figueroa E, Martinez-Jaramillo G, Mayani H. In vitro characterization of two lineage-negative CD34+ cell-enriched hematopoietic cell populations from human UC blood. Cytotherapy 2005;7:334–44.
  • Flores-Guzman P, Gutierrez-Rodriguez M, Mayani H. In vitro proliferation, expansion and differentiation of a CD34+ cell-enriched hematopoietic cell population from human umbilical cord blood in response to recombinant cytokines. Arch Med Res 2002;33:107–14.
  • Flores-Guzman P, Martinez-Jaramillo G, Mayani H. Growth kinetics of progenitor cell-enriched hematopoietic cell populations in long-term liquid cultures under continuous removal of mature cells. Cytotherapy 2006;8:299–307.
  • Wognum AW, Eaves AC, Thomas TE. Identification and isolation of hematopoietic stem cells. Arch Med Res 2003;34:461–75.
  • Flores-Figueroa E, Arana-Trejo RM, Gutiérrez-Espíndola G, Pérez-Cabrera A, Mayani H. Mesenchymal stem cells in myelodysplastic syndromes: phenotypic and cytogenetic characterization. Leuk Res 2005;29:215–24.
  • Flores-Figueroa E, Montesinos JJ, Flores-Guzmán P, . Functional analysis of myelodysplastic syndromes-derived mesenchymal stem cells. Leuk Res 2008;32:1407–16.
  • Sutherland HJ, Eaves CJ. Long-term culture of human myeloid cells. Freshney RI, Pragnell IB, Freshney MG. Culture of Hematopoietic Cells. USA: Wiley-Liss; 1994. 139–62.
  • Miller CL, Eaves CJ. Long-term culture initiating-cell assays for human and murine cells. Klug CA, Jordan CT. Hematopoietic Stem Cell Protocols. USA: Humana Press; 2002. 123–41.
  • Wang J-F, Wang L-J, Wu Y-F, . Mesenchymal stem/ progenitor cells in human umbilical cord blood as support for ex vivo expansion of CD34+ hematopoietic stem cells and for chondrogenic differentiation. Haematologica 2004;89:837–44.
  • Xie C-G, Wang J-F, Xiang Y, . Cocultivation of umbilical cord blood CD34+ cells with retro-transduced hMSC leads to effective amplification of long-term culture initiating cells. World J Gastroenterol 2006;21:393–402.
  • Wagner W, Roderburg C, Wein F, . Molecular and secretory profiles of human mesenchymal stromal cells and their abilities to maintain primitive hematopoietic progenitors. Stem Cells 2007;25:2638–47.
  • Jang YK, Jung DH, Jung MH, . Mesenchymal stem cells feeder layer from human umbilical cord blood for ex vivo expanded growth and proliferation of hematopoietic progenitor cells. Ann Hematol 2006;85:212–25.
  • Metcalf D. Hematopoietic cytokines. Blood 2008;111:485–91.
  • Zanjani ED, Almeida-Porada G, Livingston AG, Flake AW, Ogawa M. Human bone marrow CD34− cells engraft in vivo and undergo multilineage expression that includes giving rise to CD34+ cells. Exp Hematol 1998;26:353–60.
  • Bathia M, Bonnet D, Murdoch B, Gan OI, Dick J. A newly discovered class of human hematopoietic cells with SCID-repopulating activity. Nat Med 1998;4:1038–45.
  • Gallacher L, Murdoch B, Wu DM, Karanu FN, Keeney M, Bathia M. Isolation and characterization of human CD34− Lin− and CD34+ Lin− hematopoietic stem cells using cell surface markers AC133 and CD7. Blood 2000;95:2813–20.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.