Cellular magnetic resonance imaging of monocyte-derived dendritic cell migration from healthy donors and cancer patients as assessed in a scid mouse model

References

• Babatz J, Rollig C, Oelschlagel U, Zhao S, Ehninger G, Schmitz M, . Large-scale immunomagnetic selection of CD14+ monocytes to generate dendritic cells for cancer immunotherapy: a phase I study. J Hematother Stem Cell Res. 2003;12:515–23.
   PubMedGoogle Scholar
• Bracho F, van de Ven C, Areman E, Hughes RM, Davenport V, Bradley MB, . A comparison of ex vivo expanded DCs derived from cord blood and mobilized adult peripheral blood plastic-adherent mononuclear cells: decreased alloreactivity of cord blood DCs. Cytotherapy. 2003;5:349–61.
   PubMed Web of Science ®Google Scholar
• de Vries IJ, Adema GJ, Punt CJ, Figdor CG. Phenotypical and functional characterization of clinical-grade dendritic cells. Meth Mol Med. 2005;109:113–26.
   Google Scholar
• Steinman RM. Some scientific and organizational challenges in cancer immunology. Ann NY Acad Sci. 2009;1174:1–5.
   Google Scholar
• Steinman RM, Banchereau J. Taking dendritic cells into medicine. Nature. 2007;449:419–26.
   PubMed Web of Science ®Google Scholar
• Bae MY, Cho NH, Seong SY. Protective anti-tumour immune responses by murine dendritic cells pulsed with recombinant Tat-carcinoembryonic antigen derived from Escherichia coli. Clin Exp Immunol. 2009;157:128–38.
   Google Scholar
• Ni J, Nolte B, Arnold A, Fournier P, Schirrmacher V. Targeting anti-tumor DNA vaccines to dendritic cells via a short CD11c promoter sequence. Vaccine. 2009;27:5480–7.
   Google Scholar
• Zhang JK, Li J, Zhang J, Chen HB, Chen SB. Antitumor immunopreventive and immunotherapeutic effect in mice induced by hybrid vaccine of dendritic cells and hepatocarcinoma in vivo. World J Gastroenterol. 2003;9:479–84.
   PubMed Web of Science ®Google Scholar
• Um SJ, Choi YJ, Shin HJ, Son CH, Park YS, Roh MS, . Phase I study of autologous dendritic cell tumor vaccine in patients with non-small cell lung cancer. Lung Cancer. 2010;70:188–94.
   Google Scholar
• Salcedo M, Bercovici N, Taylor R, Vereecken P, Massicard S, Duriau D, . Vaccination of melanoma patients using dendritic cells loaded with an allogeneic tumor cell lysate. Cancer Immunol Immunother. 2006;55:819–29.
   PubMed Web of Science ®Google Scholar
• Saha A, Chatterjee SK. Dendritic cells pulsed with an anti-idiotype antibody mimicking Her-2/neu induced protective antitumor immunity in two lines of Her-2/neu transgenic mice. Cell Immunol. 2010;263:9–21.
   Google Scholar
• Pham TN, Hong CY, Min JJ, Rhee JH, Nguyen TA, Park BC, . Enhancement of antitumor effect using dendritic cells activated with natural killer cells in the presence of toll-like receptor agonist. Exp Mol Med. 2010;42:407–19.
   PubMed Web of Science ®Google Scholar
• Engell-Noerregaard L, Hansen TH, Andersen MH, Thor Straten P, Svane IM. Review of clinical studies on dendritic cell-based vaccination of patients with malignant melanoma: assessment of correlation between clinical response and vaccine parameters. Cancer Immunol Immunother. 2009;58:1–14.
   PubMed Web of Science ®Google Scholar
• Berntsen A, Trepiakas R, Wenandy L, Geertsen PF, thor Straten P, Andersen MH, . Therapeutic dendritic cell vaccination of patients with metastatic renal cell carcinoma: a clinical phase trial. J Immunother. 2008;31:771–80.
   PubMed Web of Science ®Google Scholar
• Avigan DE, Vasir B, George DJ, Oh WK, Atkins MB, McDermott DF, . Phase I/II study of vaccination with electrofused allogeneic dendritic cells/autologous tumor-derived cells in patients with stage IV renal cell carcinoma. J Immunother. 2007;30:749–61.
   PubMed Web of Science ®Google Scholar
• Zhou J, Weng D, Zhou F, Pan K, Song H, Wang Q, . Patient-derived renal cell carcinoma cells fused with allogeneic dendritic cells elicit anti-tumor activity: in vitro results and clinical responses. Cancer Immunol Immunother. 2009;58:1587–97.
   PubMed Web of Science ®Google Scholar
• Gitlitz BJ, Belldegrun AS, Zisman A, Chao DH, Pantuck AJ, Hinkel A, . A pilot trial of tumor lysate-loaded dendritic cells for the treatment of metastatic renal cell carcinoma. J Immunother. 2003;26:412–9.
   PubMed Web of Science ®Google Scholar
• Palucka K, Ueno H, Fay J, Banchereau J. Dendritic cells and immunity against cancer. J Internal Med. 2011;269:64–73.
   Google Scholar
• Randolph GJ, Ochando J, Partida-Sanchez S. Migration of dendritic cell subsets and their precursors. Annual review of immunology. 2008;26:293–316.
   PubMed Web of Science ®Google Scholar
• Helfer BM, Balducci A, Nelson AD, Janjic JM, Gil RR, Kalinski P, . Functional assessment of human dendritic cells labeled for in vivo 19F magnetic resonance imaging cell tracking. Cytotherapy. 2010;12:238–50.
   PubMed Web of Science ®Google Scholar
• De Vries IJ, Krooshoop DJ, Scharenborg NM, Lesterhuis WJ, Diepstra JH, Van Muijen GN, . Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res. 2003;63:12–7.
   PubMed Web of Science ®Google Scholar
• Eggert AA, Schreurs MW, Boerman OC, Oyen WJ, de Boer AJ, Punt CJ, . Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration. Cancer Res. 1999;59:3340–5.
   PubMed Web of Science ®Google Scholar
• Eggert AA, van der Voort R, Torensma R, Moulin V, Boerman OC, Oyen WJ, . Analysis of dendritic cell trafficking using EGFP-transgenic mice. Immunol Lett. 2003;89:17–24.
   PubMed Web of Science ®Google Scholar
• Josien R, Li HL, Ingulli E, Sarma S, Wong BR, Vologodskaia M, . TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivo. J Exp Med. 2000;191:495–502.
   PubMed Web of Science ®Google Scholar
• MartIn-Fontecha A, Sebastiani S, Hopken UE, Uguccioni M, Lipp M, Lanzavecchia A, . Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med. 2003;198:615–21.
   PubMed Web of Science ®Google Scholar
• Verdijk P, Aarntzen EH, Lesterhuis WJ, Boullart AC, Kok E, van Rossum MM, . Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients. Clin Cancer Res. 2009;15:2531–40.
   PubMed Web of Science ®Google Scholar
• Rezvany MR, Jeddi-Tehrani M, Biberfeld P, Soderlund J, Mellstedt H, Osterborg A, . Dendritic cells in patients with non-progressive B-chronic lymphocytic leukaemia have a normal functional capability but abnormal cytokine pattern. Br J Haematol. 2001;115:263–71.
   PubMed Web of Science ®Google Scholar
• Tjomsland V, Sandstrom P, Spangeus A, Messmer D, Emilsson J, Falkmer U, . Pancreatic adenocarcinoma exerts systemic effects on the peripheral blood myeloid and plasmacytoid dendritic cells: an indicator of disease severity? BMC Cancer. 2010;10:87.
   PubMed Web of Science ®Google Scholar
• Mohty M, Jarrossay D, Lafage-Pochitaloff M, Zandotti C, Briere F, de Lamballeri XN, . Circulating blood dendritic cells from myeloid leukemia patients display quantitative and cytogenetic abnormalities as well as functional impairment. Blood. 2001;98:3750–6.
   PubMed Web of Science ®Google Scholar
• Shields JD, Kourtis IC, Tomei AA, Roberts JM, Swartz MA. Induction of lymphoid-like stroma and immune escape by tumors that express the chemokine CCL21. Science. 2010;328:749–52.
   PubMed Web of Science ®Google Scholar
• Dekaban GA, Snir J, Shrum B, de Chickera S, Willert C, Merrill M, . Semiquantitation of mouse dendritic cell migration in vivo using cellular MRI. J Immunother. 2009; 32:240–51.
   Google Scholar
• Baumjohann D, Hess A, Budinsky L, Brune K, Schuler G, Lutz MB. In vivo magnetic resonance imaging of dendritic cell migration into the draining lymph nodes of mice. Eur J Immunol. 2006;36:2544–55.
   PubMed Web of Science ®Google Scholar
• Verdijk P, Scheenen TW, Lesterhuis WJ, Gambarota G, Veltien AA, Walczak P, . Sensitivity of magnetic resonance imaging of dendritic cells for in vivo tracking of cellular cancer vaccines. Int J Cancer. 2007;120:978–84.
   PubMed Web of Science ®Google Scholar
• de Chickera SN, Snir J, Willert C, Rohani R, Foley R, Foster PJ, Dekaban GA. Labelling dendritic cells with SPIO has implications for their subsequent in vivo migration as assessed with cellular MRI. Cont Media Mol Imag. 2011; 6:314–27.
   Google Scholar
• Schuler G. Dendritic cells in cancer immunotherapy. Eur J Immunol. 2010;40:2123–30.
   PubMed Web of Science ®Google Scholar
• Gonzalez-Lara LE, Xu X, Hofstetrova K, Pniak A, Chen Y, McFadden CD, . The use of cellular magnetic resonance imaging to track the fate of iron-labeled multipotent stromal cells after direct transplantation in a mouse model of spinal cord injury. Mol Imaging Biol. 2011;13:702–11.
   Google Scholar
• Rohani R, de Chickera SN, Willert C, Chen Y, Dekaban GA, Foster PJ. In vivo cellular MRI of dendritic cell migration using micrometer-sized iron oxide (MPIO) particles. Mol Imaging Biol. 2011;13:679–94.
   Google Scholar
• Zhang X, Divangahi M, Ngai P, Santosuosso M, Millar J, Zganiacz A, . Intramuscular immunization with a monogenic plasmid DNA tuberculosis vaccine: enhanced immunogenicity by electroporation and co-expression of GM-CSF transgene. Vaccine. 2007;25:1342–52.
   PubMed Web of Science ®Google Scholar
• Chadwick K, Wang L, Li L, Menendez P, Murdoch B, Rouleau A, . Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood. 2003;102:906–15.
   PubMed Web of Science ®Google Scholar
• Heyn C, Ronald JA, Ramadan SS, Snir JA, Barry AM, Mac-Kenzie LT, . In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain. Magn Reson Med. 2006;56:1001–10.
   PubMed Web of Science ®Google Scholar
• Heyn C, Bowen CV, Rutt BK, Foster PJ. Detection threshold of single SPIO-labeled cells with FIESTA. Magn Reson Med. 2005;53:312–20.
   PubMed Web of Science ®Google Scholar
• Palucka AK, Gatlin J, Blanck JP, Melkus MW, Clayton S, Ueno H, . Human dendritic cell subsets in NOD/SCID mice engrafted with CD34+ hematopoietic progenitors. Blood. 2003;102:3302–10.
   PubMed Web of Science ®Google Scholar
• Bulte JW. In vivo MRI cell tracking: clinical studies. Am J Roentgenol. 2009;193:314–25.
   PubMed Web of Science ®Google Scholar
• Lehner M, Stilper A, Morhart P, Holter W. Plasticity of dendritic cell function in response to prostaglandin E2 (PGE2) and interferon-gamma (IFN-gamma). J Leuk Biol. 2008; 83:883–93.
   PubMed Web of Science ®Google Scholar
• Rojas D, Krishnan R. IFN-gamma generates maturation-arrested dendritic cells that induce T cell hyporesponsiveness independent of Foxp3+ T-regulatory cell generation. Immunol Letters. 2010;132:31–7.
   Google Scholar
• Stranges PB, Watson J, Cooper CJ, Choisy-Rossi CM, Stonebraker AC, Beighton RA, . Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity. Immunity. 2007;26:629–41.
   PubMed Web of Science ®Google Scholar
• Xia Z, Taylor PR, Locklin RM, Gordon S, Cui Z, Triffitt JT. Innate immune response to human bone marrow fibroblastic cell implantation in CB17 scid/beige mice. J Cell Biochem. 2006;98:966–80.
   Google Scholar