Early endothelial progenitor cells in bone marrow are a biomarker of cell therapy success in patients with critical limb ischemia

References

• Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, . Isolation of putative progenitor endothelial cells for angiogenesis. Science. 1997;275:964–7.
   PubMed Web of Science ®Google Scholar
• Smadja DM, Cornet A, Emmerich J, Aiach M, Gaussem P. Endothelial progenitor cells: characterization, in vitro expansion, and prospects for autologous cell therapy. Cell Biol Toxicol. 2007;23:223–39.
   PubMedGoogle Scholar
• Cannon RO 3rd, Dunbar CE. BM-derived cell therapies for cardiovascular disease. Cytotherapy. 2007;9:305–15.
   PubMedGoogle Scholar
• Mund JA, Ingram DA, Yoder MC, Case J. Endothelial progenitor cells and cardiovascular cell-based therapies. Cytotherapy. 2009;11:103–13.
   PubMed Web of Science ®Google Scholar
• Fadini GP, Agostini C, Avogaro A. Autologous stem cell therapy for peripheral arterial disease meta-analysis and systematic review of the literature. Atherosclerosis. 2010;209:10–7.
   PubMed Web of Science ®Google Scholar
• Hur J, Yoon CH, Kim HS, Choi JH, Kang HJ, Hwang KK, . Characterization of two types of endothelial progenitor cells and their different contributions to neovasculogenesis. Arterioscler Thromb Vasc Biol. 2004;24:288–93.
   PubMed Web of Science ®Google Scholar
• Hill JM, Zalos G, Halcox JP, Schenke WH, Waclawiw MA, Quyyumi AA, . Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med. 2003;348:593–600.
   PubMed Web of Science ®Google Scholar
• Hur J, Yang HM, Yoon CH, Lee CS, Park KW, Kim JH, . Identification of a novel role of T cells in postnatal vasculogenesis: characterization of endothelial progenitor cell colonies. Circulation. 2007;116:1671–82.
   PubMed Web of Science ®Google Scholar
• Vasa M, Fichtlscherer S, Aicher A, Adler K, Urbich C, Martin H, . Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res. 2001;89:E1–7.
   PubMed Web of Science ®Google Scholar
• Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, Link A, . Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med. 2005;353:999–1007.
   PubMed Web of Science ®Google Scholar
• Smadja DM, Godier A, Susen S, Packard RR, Fabiani JN, Aiach M, . Endothelial progenitor cells are selectively mobilised immediately after coronary artery bypass grafting or valve surgery. Thromb Haemost. 2009;101:983–5.
   PubMedGoogle Scholar
• Yoder MC, Mead LE, Prater D, Krier TR, Mroueh KN, Li F, . Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals. Blood. 2007;109:1801–9.
   PubMed Web of Science ®Google Scholar
• Huang L, Critser PJ, Grimes BR, Yoder MC. Human umbilical cord blood plasma can replace fetal bovine serum for in vitro expansion of functional human endothelial colony-forming cells. Cytotherapy. 2011;13:712–21.
   PubMed Web of Science ®Google Scholar
• Guven H, Shepherd RM, Bach RG, Capoccia BJ, Link DC. The number of endothelial progenitor cell colonies in the blood is increased in patients with angiographically significant coronary artery disease. J Am Coll Cardiol. 2006;48: 1579–87.
   PubMed Web of Science ®Google Scholar
• Massa M, Campanelli R, Bonetti E, Ferrario M, Marinoni B, Rosti V. Rapid and large increase of the frequency of circulating endothelial colony-forming cells (ECFCs) generating late outgrowth endothelial cells in patients with acute myocardial infarction. Exp Hematol. 2009;37:8–9.
   PubMedGoogle Scholar
• Smadja DM, Mauge L, Gaussem P, d'Audigier C, Israel-Biet D, Celermajer DS, . Treprostinil increases the number and angiogenic potential of endothelial progenitor cells in children with pulmonary hypertension. Angiogenesis. 2011; 14:17–27.
   PubMedGoogle Scholar
• Toshner M, Voswinckel R, Southwood M, Al-Lamki R, Howard LS, Marchesan D, . Evidence of dysfunction of endothelial progenitors in pulmonary arterial hypertension. Am J Respir Crit Care Med. 2009;180:780–7.
   PubMed Web of Science ®Google Scholar
• Sandri M, Adams V, Gielen S, Linke A, Lenk K, Krankel N, . Effects of exercise and ischemia on mobilization and functional activation of blood-derived progenitor cells in patients with ischemic syndromes: results of 3 randomized studies. Circulation. 2005;111:3391–9.
   PubMed Web of Science ®Google Scholar
• Shaffer RG, Greene S, Arshi A, Supple G, Bantly A, Moore JS, . Effect of acute exercise on endothelial progenitor cells in patients with peripheral arterial disease. Vasc Med. 2006;11:219–26.
   PubMed Web of Science ®Google Scholar
• Fadini GP, Sartore S, Albiero M, Baesso I, Murphy E, Menegolo M, . Number and function of endothelial progenitor cells as a marker of severity for diabetic vasculopathy. Arterioscler Thromb Vasc Biol. 2006;26:2140–6.
   PubMed Web of Science ®Google Scholar
• Delva P, De Marchi S, Prior M, Degan M, Lechi A, Trettene M, . Endothelial progenitor cells in patients with severe peripheral arterial disease. Endothelium. 2008;15:246–53.
   PubMed Web of Science ®Google Scholar
• Tateishi-Yuyama E, Matsubara H, Murohara T, Ikeda U, Shintani S, Masaki H, . Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial. Lancet. 2002;360:427–35.
   PubMed Web of Science ®Google Scholar
• Duong-Van-Huyen JP, Smadja DM, Bruneval P, Gaussem P, Dal-Cortivo L, Julia P, . Bone marrow-derived mononuclear cell therapy induces distal angiogenesis after local injection in critical leg ischemia. Mod Pathol. 2008;21:837–46.
   PubMedGoogle Scholar
• Heeschen C, Lehmann R, Honold J, Assmus B, Aicher A, Walter DH, . Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease. Circulation. 2004; 109:1615–22.
   PubMed Web of Science ®Google Scholar
• Smadja DM, Bieche I, Silvestre JS, Germain S, Cornet A, Laurendeau I, . Bone morphogenetic proteins 2 and 4 are selectively expressed by late outgrowth endothelial progenitor cells and promote neoangiogenesis. Arterioscler Thromb Vasc Biol. 2008;28:2137–43.
   PubMed Web of Science ®Google Scholar
• Smadja DM, d'Audigier C, Bieche I, Evrard S, Mauge L, Dias JV, . Thrombospondin-1 is a plasmatic marker of peripheral arterial disease that modulates endothelial progenitor cell angiogenic properties. Arterioscler Thromb Vasc Biol. 2011; 31:551–9.
   PubMed Web of Science ®Google Scholar
• Hansen S, Grabau DA, Sorensen FB, Bak M, Vach W, Rose C. The prognostic value of angiogenesis by Chalkley counting in a confirmatory study design on 836 breast cancer patients. Clin Cancer Res. 2000;6:139–46.
   PubMed Web of Science ®Google Scholar
• Beaujean F, Hartmann O, Kuentz M, Le Forestier C, Divine M, Duedari N. A simple, efficient washing procedure for cryopreserved human hematopoietic stem cells prior to reinfusion. Bone Marrow Transplant. 1991;8:291–4.
   PubMed Web of Science ®Google Scholar
• Preti RA, Ahmed T, Ayello J, Helson L, Argani I, Wuest D, . Hemopoietic stem cell processing: comparison of progenitor cell recovery using the Cobe 2991 cell washer and the Haemonetics V50 apheresis system. Bone Marrow Transplant. 1992;9:377–81.
   PubMed Web of Science ®Google Scholar
• Six EM, Bonhomme D, Monteiro M, Beldjord K, Jurkowska M, Cordier-Garcia C, . A human postnatal lymphoid progenitor capable of circulating and seeding the thymus. J Exp Med. 2007;204:3085–93.
   PubMedGoogle Scholar
• Purhonen S, Palm J, Rossi D, Kaskenpaa N, Rajantie I, Yla-Herttuala S, . Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. Proc Natl Acad Sci USA. 2008;105:6620–5.
   PubMed Web of Science ®Google Scholar
• Dudley AC, Udagawa T, Melero-Martin JM, Shih SC, Curatolo A, Moses MA, . Bone marrow is a reservoir for proangiogenic myelomonocytic cells but not endothelial cells in spontaneous tumors. Blood. 2010;116:3367–71.
   PubMed Web of Science ®Google Scholar
• Urbich C, Aicher A, Heeschen C, Dernbach E, Hofmann WK, Zeiher AM, . Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. J Mol Cell Cardiol. 2005;39:733–42.
   PubMed Web of Science ®Google Scholar
• Ingram DA, Mead LE, Moore DB, Woodard W, Fenoglio A, Yoder MC. Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells. Blood. 2005;105:2783–6.
   PubMed Web of Science ®Google Scholar
• Walter DH, Krankenberg H, Balzer JO, Kalka C, Baumgartner I, Schluter M, . Intraarterial administration of bone marrow mononuclear cells in patients with critical limb ischemia: a randomized-start, placebo-controlled pilot trial (PROVASA). Circ Cardiovasc Interv. 2011;4:26–37.
   PubMed Web of Science ®Google Scholar
• Hiatt WR, Baumgartner II, Van Belle E, Driver VR, Norgren L, Belch JJ. NV1FGF gene therapy on amputation-free survival in critical limb ischemia - phase 3 randomized double-blind placebo-controlled trial. Late-Breaking Clinical Trials, Abstracts AHA 2010 21790. Circulation. 2010.
   PubMedGoogle Scholar
• Dudek AZ. Endothelial lineage cell as a vehicle for systemic delivery of cancer gene therapy. Transl Res. 2010;156:136–46.
   PubMed Web of Science ®Google Scholar
• Marboeuf P, Corseaux D, Mouquet F, Van Belle E, Jude B, Susen S. Inflammation triggers colony forming endothelial cell mobilization after angioplasty in chronic lower limb ischemia. J Thromb Haemost. 2008;6:195–7.
   PubMedGoogle Scholar
• Ingram DA, Mead LE, Tanaka H, Meade V, Fenoglio A, Mortell K, . Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood. 2004;104:2752–60.
   PubMed Web of Science ®Google Scholar
• Au P, Daheron LM, Duda DG, Cohen KS, Tyrrell JA, Lanning RM, . Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels. Blood. 2008;111:1302–5.
   PubMed Web of Science ®Google Scholar
• Vanneaux V, El-Ayoubi F, Delmau C, Driancourt C, Lecourt S, Grelier A, . In vitro and in vivo analysis of endothelial progenitor cells from cryopreserved umbilical cord blood: are we ready for clinical application? Cell Transplant. 2010;19: 1143–55.
   PubMedGoogle Scholar
• Broxmeyer HE, Lee MR, Hangoc G, Cooper S, Prasain N, Kim YJ, . Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood. Blood. 2011;117:4773–7.
   PubMed Web of Science ®Google Scholar
• Kim SW, Han H, Chae GT, Lee SH, Bo S, Yoon JH, . Successful stem cell therapy using umbilical cord blood-derived multipotent stem cells for Buerger's disease and ischemic limb disease animal model. Stem Cells. 2006;24:1620–6.
   PubMed Web of Science ®Google Scholar
• Melero-Martin JM, De Obaldia ME, Kang SY, Khan ZA, Yuan L, Oettgen P, . Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells. Circ Res. 2008;103: 194–202.
   PubMed Web of Science ®Google Scholar