References
- Kwan P, Brodie MJ. Early identification of refractory epilepsy. N Engl J Med 2000;342:314–319.
- Carroll BJ, Curtis GC, Mendels J. Neuroendocrine regulation in depression. II Discrimination of depressed from non-depressed patients. Arch Gen Psychol 1973;33:1051–1057.
- Ellison G, Eison MS, Huberman HS, Daniel F. Long-term changes in dopaminergic innervation of caudate nucleus after continuous amphetamine administration. Science 1978;201:276–278.
- Worthen DR, Bence AK, Stables JP, Crooks PA. In vivo evaluation of diaminodiphenyls: anticonvulsant agents with minimal acute neurotoxicity. Bioorg Med Chem Lett 2009;19:5012–5015.
- Johannessen Landmark C, Johannessen LC. Pharmacological management of epilepsy: recent advances and future prospects. Drugs 2008;68:1925–1939.
- Snead OC, Donner EJ. A new generation of anticonvulsants for the treatment of epilepsy in children. Paediatr Child Health 2007;12:741–744.
- Verma M, Chaturvedi AK, Chaudhari A, Parmar SS. Monoamine oxidase inhibitory and anticonvulsant properties of 1,2,4-trisubstituted 5-imidazolones. J Pharm Sci 1974;63:1740–1744.
- Naithani PK, Srivastava VK, Barthwal JP, Saxena AK, Gupta TK, Shanker K, Synthesis and antiparkinsonian activity of newer imidazolones. Indian J Chem 1989;28:990–992
- Harfenist M, Soroko FE, McKenzie GM. 2-(Alkoxyaryl)-2-imidazoline monoamine oxidase inhibitors with antidepressant activity. J Med Chem 1978;21:405–409.
- Magd-El-Din AA, Abd-El-All AS, Roaiah HMF, El-Baroudy MMS. New synthesis of furochromenyl imidazo [2a-1b] thiazole derivatives, studies on their antitumor activities. J Am Sci 2010;6:251–256.
- Desai NC, Bhavsar AM, Baldaniya BB. Synthesis and antimicrobial activity of 5-imidazolinone derivatives. Indian J Pharm Sci 2009;71:90–94.
- Joshi H, Upadhyay P, Karia D, Baxi AJ. Synthesis of some novel imidazolinones as potent anticonvulsant agents. Eur J Med Chem 2003;38:837–840.
- Siddiqui SA, Bhusare SR, Jorikot DV, Pawa RP, Vibhute YB. New novel synthesis and antibacterial activity of 1-(substituted phenyl)-2-phenyl-4-(3′-halo, 4′-hydroxy, 5′-methoxy benzylidene)-imidazole-5-ones. Bull Korean Chem Soc 2001;22:1033–1036.
- Patel HJ, Sarra J, Caruso F, Rossi M, Doshi U, Stephani RA. Synthesis and anticonvulsant activity of new N-1′,N-3′-disubstituted-2′H,3H,5′H-spiro-(2-benzofuran-1,4′-imidazolidine)-2′,3,5′-triones. Bioorg Med Chem Lett 2006;16:4644–4647.
- Librowski T, Kubacka M, Meusel M, Scolari S, Müller CE, Gütschow M. Evaluation of anticonvulsant and analgesic effects of benzyl- and benzhydryl ureides. Eur J Pharmacol 2007;559:138–149.
- Bhusare SR, Patil PS, Chavan VP, Pawar RP, Bhawal BM, Vibhute YB. Synthesis of 1-(substituted phenyl)-2-phenyl-4- (2′-hydroxy 3′-iodo-5′-choro benzylidene) -imidazole-5-ones. Mendeleev Commun 2002;12:94–95.
- Thiry A, Dogné JM, Supuran CT, Masereel B. Anticonvulsant sulfonamides/sulfamates/sulfamides with carbonic anhydrase inhibitory activity: drug design and mechanism of action. Curr Pharm Des 2008;14:661–671.
- Masereel B, Rolin S, Abbate F, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties. J Med Chem 2002;45:312–320.
- Wilhelm H, Regina T, Michael W. The virtual laboratory approaches to pharmacokinetics: design principles and concepts. Drug Dis Today 2006;11:800–805.
- Dearden JC. In silico prediction of drug toxicity. J Comput Aided Mol Des 2003;17:119–127.
- Sean E, John R. In silico ADME/Tox: the state of the art. J Mol Graph Model 2002;20:305–309.
- Moorthy HN, Singh RJ, Singh HP, Gupta SD. Synthesis, biological evaluation and in silico metabolic and toxicity prediction of some flavanone derivatives. Chem Pharm Bull 2006;54:1384–1390.
- Moorthy HN, Karthikeyan C, Trivedi P. Design, synthesis, cytotoxic evaluation, and QSAR study of some 6H-indolo[2,3-b]quinoxaline derivatives. J Enzyme Inhib Med Chem 2010;25:394–405.
- Hari Narayana Moorthy HN, Karthikeyan C, Trivedi P. Synthesis, cytotoxic evaluation and in silico pharmacokinetic prediction of some benzo[a]phenazine-5-sulfonic acid derivatives. Med Chem 2009;5:549–557.
- Pallas 3.1.1.2., ADME-Tox software, CompDrug International Inc., USA; 2000.
- q-ADME, q-Tox and q-hERG software 2008, developed by Quantum Pharmaceuticals, Moscow, Russia; 2008. http://www.q-lead.com/.