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Original Article

Synthesis and in vitro biological evaluation of new heterocycles based on the indole moiety

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Pages 140-151 | Received 13 Jan 2014, Accepted 06 Feb 2014, Published online: 31 Mar 2014

References

  • Karthikeyan MS, Prasal DJ, Poojary B, et al. Synthesis and spectroscopic studies on ternary bis-Schiff base complexes having oxygen and/or nitrogen donors. J Coord Chem 2006;59:157–76
  • Panneerselvam P, Nair RR, Vijayalakshmi G, et al. Synthesis of Schiff bases of 4-(4-aminophenyl) morpholine as potential antimicrobial agents. Eur J Med Chem 2005;40:225–9
  • Mladenova R, Ignatova M, Manolova N, et al. Preparation, characterization and biological activity of Schiff base compounds derived from 8-hydroxyquinoline-2-carboxaldehyde and Jeffamines. Eur J Polym 2002;38:989–99
  • Kumar S, Dhar DN, Saxena PN. Application of metal complexes of Schiff bases – a review. J Sci Ind Res 2009;68:181–7
  • Ajaykumar D, Patil AS, Badam SP. Electrochemical properties of some transition metal complexes. Synthesis, characterization and in vitro antimicrobial studies of Co(II), Ni(II), Cu(II), Mn(II) and Fe(III) complexes. Int J Electrochem Sci 2009;4:717–29
  • Sandras K, Blaga CR, Zivojin C, Vensa V. Synthesis and characterization of Co(II), Ni(II), Cu(II) and Zn(II) complexes with 3-salicylidenehydrazono-2-indolinone. J Serb Chem Soc 2003;8–9:641–7
  • Kobayashi J, Tsuda M, Agemi K, et al. Purealidins B and C new bromotyrosine alkaloids from the Okinawan marine sponge Psammaplysilla purea. Tetrahedron 1991;47:6617–22
  • James DM, Kunze HB, Faulkner DJ. Two new brominated tyrosine derivatives from the sponge Druinella (Psammaplysilla) purpurea. J Nat Prod 1991;54:1137–40
  • Da-Silva JFM, Garden SJ, Pinto AC. The chemistry of isatins: a review from 1975 to 1999. J Braz Chem Soc 2001;12:273–324
  • Joshi KC, Chand P. Biologically active indole derivatives. Pharmazie 1982;37:1–12
  • Abdel-Rahman AH, Keshk EM, Hanna MA, El-Bady Sh M. Synthesis and evaluation of some new spiro-indoline-based heterocycles as potentially active antimicrobial agents. Bioorg Med Chem 2004;12:2483–8
  • Dandia A, Singh R, Khaturia S, et al. Efficient microwave enhanced regioselective synthesis of a series of benzimidazolyl/triazolyl spiro[indole-thiazolidinones] as potent antifungal agents and crystal structure of spiro[3H-indole-3,2′-thiazolidine]-3′(1,2,4-triazol-3-yl)-2,4′(1H)-dione. Bioorg Med Chem 2006;4:2409–17
  • Khafagy MM, El-Wahas AHFA, Eid FA, El-Agrody AM. Synthesis of halogen derivatives of benzo[h]chromene and benzo[a]anthracene with promising antimicrobial activities. Farmaco 2002;57:715–22
  • Sebahar PR, Williams RM. The asymmetric total synthesis of (+) and (−)-spirotryprostatin B. J Am Chem Soc 2000;122:5666–7
  • Ma J, Hecht SM. Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton. Chem Commun 2004;20:1190–1
  • Edmondson S, Danishefsky SJ, Sepp-lorenzinol L, Rosen N. Total synthesis of spirotryprostatin A, leading to the discovery of some biologically promising analogues. J Am Chem Soc 1999;121:2147–55
  • Singh GS, Mmolotsi BJ. Synthesis of 2-azetidinones from 2-diazo-1,2-diaryl ethanones and N-(2-thienylidene) imines as possible antimicrobial agents. Il Farmaco 2005;60:727–30
  • Rahman VPM, Mukhtar S, Ansari WH, Lemiere G. Synthesis, stereochemistry and biological activity of some novel long alkyl chain substituted thiazolidin-4-ones and thiazan-4-one from 10-undecenoic acid hydrazide. Eur J Med Chem 2005;40:173–84
  • Kucukguzel SG, Oruc EE, Rollas S, et al. Synthesis, characterization and biological activity of novel 4-thiazolidinones, 1,3,4-oxadiazoles and some related compounds. Eur J Med Chem 2002;37:197–206
  • Rawal RK, Prabhakar YS, Katti SB, De Clercq E. 2-(Aryl)-3-furan-2-yl-methyl-thiazolidin-4-ones as selective HIV-RT inhibitors. Bioorg Med Chem 2005;13:6771–6
  • Vigorita MG, Ottana R, Monforte F, et al. Synthesis and antiinflammatory, analgesic activity of 3,3′-(1-2-ethanediyl)-bis-[2-aryl-4-thiazolidinone] chiral compounds part 10. Bioorg Med Chem Lett 2001;11:2791–4
  • Goel B, Ram T, Tyagi R, et al. 2-Substituted-3-(4-bromo-2-carboxyphenyl)-5-methyl-4-thiazolidinones as potential anti-inflammatory agents. Eur J Med Chem 1999;34:265–9
  • Dandia A, Singh R, Sachdeva H, Arya K. Microwave assisted one pot synthesis of a series of trifluoromethyl substituted spiro[indoletriazoles. J Fluorine Chem 2001;111:61–7
  • Mohamed MI, Zaky HT, Mohamed HM, Kandile NG. Synthesis and antibacterial activity of some pyridazine derivatives. J Chin Chem Soc 2004;51:963–8
  • Mohamed MI. Synthesis and antimicrobial activity of new pyridazinyl sulfonamide derivatives. Bulg Chem Commun 2007;39:152–8
  • Kandile NG, Mohamed MI, Zaky HT, Mohamed HM. Synthesis and antibacterial activity of some pyridazine derivatives. Eur J Med Chem 2009;44:1989–96
  • Kandile NG, Mohamed MI, Zaky HT, Mohamed HM. Silver nanoparticles effect on antimicrobial and antifungal activity of new heterocycles. Bull Korean Chem Soc 2010;31:3530–8
  • Mohamed MI. Synthesis and antibacterial activity of some novel heterocycles. Bulg Chem Commun 2004;36:241–8
  • Kandile NG, Mohamed MI, Ismaeel HM. Antiproliferative effects of metal complexes of new isatin hydrazones against HCT116, MCF7 and HELA tumour cell lines. J Enzyme Inhib Med Chem 2012;27:330–8
  • Kandile NG, Zaky HT, Mohamed MI, et al. Synthesis, characterization and in vitro antimicrobial evaluation of new compounds incorporating oxindole nucleus. J Enzyme Inhib Med Chem 2012;27:599–608
  • Ahmad S, Rathish IG, Bano S, et al. Synthesis and biological evaluation of some novel 6-aryl-2-(psulfamylphenyl)-4,5-dihydropyridazin-3(2H)-ones as anti-cancer, antimicrobial, and anti- Inflammatory agents. J Enzyme Inhib Med Chem 2010;25:266–71
  • Skehan P, Storeng R, Scudiero D, et al. New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 1990;82:1107–12
  • Roth I, Brakovic D, Pomer S, Ponstingl H. Synergistic antitumor effects of vinblastine sulfate, its photoactivatable derivative Napavin and laser irradiation in murine renal carcinoma. J Cancer Res Clin Oncol 1995;121:A58
  • Mohamed MI, Zaky HT, Mohamed HM, Kandile NG. Novel heterocyclic systems of pyridazines. Afinidad 2005;62:48–56

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