1,010
Views
24
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH REPORTS

Adverse reactions to injectable soft tissue fillers: Memorable cases and their clinico-pathological overview

, , , &
Pages 102-108 | Received 15 Jul 2014, Accepted 16 Sep 2014, Published online: 16 Oct 2014

References

  • Ozturk CN, Li Y, Tung R, Parker L, Piliang MP, Zins JE. Complications following injection of soft-tissue fillers. Aesthet Surg J. 2013;33:862–877.
  • Park TH, Seo SW, Kim JK, Chang CH. Clinical outcome in a series of 173 cases of foreign body granuloma: improved outcomes with a novel surgical technique. Facial Plast Reconstr Aesthet Surg. 2012;1:29–34.
  • Gladstone HB, Cohen JL. Adverse effects when injecting facial fillers. Semin Cutan Med Surg. 2007;26:34–39.
  • Requena L, Requena C, Christensen L, Zimmermann US, Kutzner H, Cerroni L. Adverse reactions to injectable soft tissue fillers. J Am Acad Dermatol. 2011;64:1–34.
  • Park TH, Seo SW, Kim JK, Chang CH. Clinical experience with hyaluronic acid filler complications. J Plast Reconstr Aesthet Surg. 2011;64:892–896.
  • Daines SM, Williams EF. Complications associated with injectable soft-tissue fillers: a 5-year retrospective review. JAMA Facial Plast Surg. 2013;15:226–231.
  • Lupton JR, Alster TS. Cutaneous hypersensitivity reaction to injectable hyaluronic acid gel. Dermatol Surg. 2000;26: 135–137.
  • Arron ST, Neuhaus IM. Persistent delayed-type hypersensitivity reaction to injectable non-animal-stabilized hyaluronic acid. J Cosmet Dermatol. 2007;6:167–171.
  • Andre P. Evaluation of the safety of a non-animal stabilized hyaluronic acid (NASHA-Q medical, Sweden) in European countries: a retrospective study from 1997 to2001. J Eur Acad Dermatol Venereol.2004;18:422–425.
  • Lowe NJ, Maxwell CA, Lowe P, Duick MG, Shah K. Hyaluronic acid skin fillers: adverse reactions and skin testing. J Am Acad Dermatol. 2001;45:930–933.
  • Andre P, Lowe NJ, Parc A, Clerici TH, Zimmermann U. Adverse reactions to dermal fillers: a review of European experiences. J Cosmet Laser Ther. 2005;7:171–176.
  • Siegle RJ, McCoy JP, Schade W, Swanson NA. Intradermal implantation of bovine collagen. Humoral immune responses associated with clinical reactions. Arch Dermatol. 1984;120:183–187.
  • Stegman S, Chu S, Armstrong R. Adverse reactions to bovine collagen implant: clinical and histological features. J Dermatol Surg Oncol. 1988;14:39–48.
  • Chrastil-La Towsky B, Wesley NO, MacGregor JL, Kaminer MS, Arndt KA. Delayed inflammatory reaction to bio-alcamid polyacrylamide gel used for soft-tissue augmentation. Arch Dermatol. 2009;145:1309–1312.
  • Cheng NX, Xu SL, Deng H, Ding XB, Zhang XM, Wu DH, et al. Migration of implants: a problem with injectable polyacrylamide gel in aesthetic plastic surgery. Aesthetic Plast Surg. 2006;30:215–225.
  • Sa HK, Woo KI, Suh YL, Kim YD. Periorbital lipogranuloma: a previously unknown complication of autologous fat injections for facial augmentation. Br J Opthalmol. 2011;95:1259–1263.
  • Malik S, Mehta P, Adesanya O, Ahluwalia HS. Migrated peiocular filler masquerading as arteriovenous malformation: a diagnostic and therapeutic dilemma. Ophthal Plast Reconstr Surg. 2013;29:18–20.
  • Lee MJ, Sung MS, Kim NJ, Choung HK, Khwarg SI. Eyelid mass secondary to injection of calcium hydroxylapatite facial filler. Opthal Plast Reconstr Surg. 2008;24:421–423.
  • Gundeslioglu AO, Hakverdi S, Erdem O, Ozen EC, Inan I, Emilk D. Axillary lipogranuloma mimicking carcinoma metastasis after silicon breast implant rupture: a case report. J Plast Reconstr Aesthet Surg. 2013;66:72–75.
  • Breiting V, Aasted A, Jorgensen A, Opitz P, Rosetzsky A. A study on patients treated with polyacrylamide hydrogel injection for facial corrections. Aesthetic Plast Surg. 2004; 28:45–53.
  • Park KY, Son IP, Li K, Seo SJ, Hong CK. Reticulate erythema after nasolabial fold injection with hyaluronic acid: the importance of immediate attention. Dermatol Surg. 2011;37: 1697–1699.
  • Grunebaum LD, Bogdan Allemann I, Dayan S, Mandy S, Baumann L. The risk of alar necrosis associated with dermal filler injection. Dermatol Surg. 2009;35:1635–1640.
  • Kleydman K, Cohen JL, Marmur E. Nitroglycerin: a review of its use in the treatment of vascular occlusion after soft tissue augmentation. Dermatol Surg. 2012;38:1889–1897.
  • Kwon DY, Park MH, Koh SB, Dhong ES, Baek SH, Ryu HJ, Park KW. Multiple arterial embolism after illicit intranasal injection of collagenous material. Dermatol Surg. 2010;36: 1196–1199.
  • Kim YJ, Kim SS, Song WK, Lee SY, Yoon JS. Ocular ischemia with hypotony after injection of hyaluronic acid gel. Ophthal Plast Reconstr Surg. 2011;27:152–155.
  • Sung MS, Kim HG, Woo KI, Kim YD. Ocular ischemia and ischemic oculomotor nerve palsy after vascular embolization of injectable calcium hydoxylapatite filler. Ophthal Plast Reconstr Surg. 2010;26:289–291.
  • Peter S, Mennel S. Retinal branch artery occlusion following injection of hyaluronic acid (Restylane). Clin Experiment Ophthalmol. 2006;34:363–364.
  • Di Benedetto G, Pierangeli M, Scalise A, Bertani A. Paraffin oil injection in the body: an obsolete and destructive procedure. Ann Plast Surg. 2002;49:391–396.
  • Legaspi-Vicerra ME, Field LM. Paraffin granulomata, “Witch's Chin” and nasal deformities. J Clin Aesthet Dermatol. 2010;3:54–58.
  • Ellis LZ, Cohen JL, High W. Granulomatous reaction to silicone injection. J Clin Aesthet Dermatol. 2012;5:44–47.
  • Sinrachtanant C, Tantinikorn W, Warnnissorn M, Assanasen P. Sclerosing lipogranuloma of the nose: a new treatment using adipose tissue transplantation. Facial Plast Surg. 2003;19: 363–367.
  • Vargas-Machuca I, Gonzalez-Guerra E, Angulo J, del Carmen Farina M, Martin L, Requena L. Facial granulomas secondary to Dermalive microimplants: reports of a case with histopathologic differential diagnosis among the granulomas secondary to different injectable permanent filler materials. Am J Dermatopathol. 2006;28:173–177.
  • Rohrich RJ, Monheit G, Nguyen AT, Brown SA, Fagien S. Soft-tissue filler complications: the important role of biofilms. Plast Reconstr Surg. 2010;125:1250–1256.
  • Dayan SH, Arkins JP, Brindise R. Soft tissue fillers and biofilms. Facial Plast Surg. 2011;27:23–28.
  • Bjarnsholt T, Tolker-Nielsen T, Givskov M, Janssen M, Christensen LH. Detection of bacteria by fluorescence in sity hybridization in culture-negative soft tissue filler lesions. Dermatol Surg. 2009;35:1620–1624.
  • Vazquez-Martinez OT, Ocampo-Candiani J, Mendez-Olvera N, Sanchez Negron FA. Paraffinomas of the facial area: treatment with systemic and intralesional steroids. J Drugs Dermatol. 2005;5:186–189.
  • Lowe NJ, Maxwell CA, Patnaik R. Adverse reactions to dermal fillers: Review. Dermatol Surg. 2005;31:1616–1625.
  • Nyhlen A, Ljungberg B, Nilsson-Ehle I, Odenholt I. Bacterial effect of combination of antibiotic and neoplastic agents against Staphylococcus aureus and Escherichia coli. Chemotherapy 2002;48:71–77.
  • Wolfram D, Tzankov A, Hildegunde PK. Surgey for foreign body reactions due to injectable fillers. Dermatology. 2006; 213:300–304.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.