222
Views
13
CrossRef citations to date
0
Altmetric
Original Article

Pharmacokinetics of metronidazole in pregnant patients with bacterial vaginosis

, , , , , & show all
Pages 444-448 | Received 06 Apr 2010, Accepted 27 May 2010, Published online: 07 Jul 2010

References

  • Sobel JD. Vaginitis in adult women. Obstet Gynecol Clin N Am 1990;17:851–879.
  • Eschenbach DA, Gravett MG, Chen KC, Hoyme UB, Holmes KK. Bacterial vaginosis during pregnancy. An association with prematurity and postpartum complications. Scand J Urol Nephrol 1984;86(suppl):213–222.
  • Gravett MG, Nelson HP, Derouen T, Critchlow C, Eschenbach DA, Holmes KK. Independent associations of bacterial vaginosis and chlamydia-trachomatis infection with adverse pregnancy outcome. JAMA 1986;256:1899–1903.
  • Kurki T, Sivonen A, Renkonen OV, Savia E, Ylikorkala O. Bacterial vaginosis in early-pregnancy and pregnancy outcome. Obstet Gynecol 1992;80:173–177.
  • Riduan JM, Hillier SL, Utomo B, Wiknjosastro G, Linnan M, Kandun N. Bacterial vaginosis and prematurity in indonesia – association in early and late pregnancy. Am J Obstet Gynecol 1993;169:175–178.
  • Meis PJ, Goldenberg RL, Mercer B, Moawad A, Das A, McNellis D, Johnson F, Iams JD, Thom E, Andrews WW. The preterm prediction study – significance of vaginal infections. Am J Obstet Gynecol 1995;173:1231–1235.
  • Mcdonald HM, Oloughlin JA, Jolley P, Vigneswaran R, Mcdonald PJ. Prenatal microbiological risk-factors associated with preterm birth. Br J Obstet Gynaecol 1992;99:190–196.
  • Watts DH, Krohn MA, Hillier SL, Eschenbach DA. The association of occult amniotic-fluid infection with gestational-age and neonatal outcome among women in preterm labor. Obstet Gynecol 1992;79:351–357.
  • Newton ER, Prihoda TJ, Gibbs RS. A clinical and microbiologic analysis of risk-factors for puerperal endometritis. Obstet Gynecol 1990;75:402–406.
  • Schwebke JR. Metronidazole: utilization in the obstetric and gynecologic patient. Sex Transm Dis 1995;22:370–376.
  • Jerve F, Berdal TB, Bohman P, Smith CC, Evjen OK, Gjønnaess H, Gaasemyr M, Hausken L, Hesla K, Hoftvedt E. Metronidazole in the treatment of non-specific vaginitis (Nsv). Br J Vener Dis 1984;60:171–174.
  • Eschenbach DA, Critchlow CW, Watkins H, Smith K, Spiegel CA, Chen KC, Holmes KK. A dose-duration study of metronidazole for the treatment of nonspecific vaginosis. Scand J Infect Dis 1983;73–80.
  • Blackwell A, Fox A, Phillips I, Barlow D. Metronidazole in treatment of non-specific vaginitis. Clinical and microbiological findings in ten patients given 2 grams of metronidazole. Scand J Infect Dis 1983;40(suppl):103–106.
  • Koumans EH, Markowitz LE, Hogan V. Indications for therapy and treatment recommendations for bacterial vaginosis in nonpregnant and pregnant women: a synthesis of data. Clin Infect Dis 2002;35:S152–S172.
  • Amon I. Placental-transfer of metronidazole. J Perinat Med 1985;13:97–98.
  • Amon I, Huller H, Amon K. Metronidazole pharmacokinetics in non-pregnant women, gravidae and women in childbed. Proceedings of VIIth International Congress Chemotherapy, 1971. Munich: Urban & Schwarzenberg; 1972, pp 111–112.
  • Visser AA, Hundt HKL. The pharmacokinetics of a single intravenous dose of metronidazole in pregnant patients. J Antimicrob Chemother 1984;13:279–283.
  • Amon I, Amon K, Huller H. Pharmacokinetics and therapeutic efficacy of metronidazole at different dosages. Int J Clin Pharmacol Biopharm 1978;16:384–386.
  • Schwartz DE, Jeunet F. Comparative pharmacokinetic studies of ornidazole and metronidazole in man. Chemotherapy 1976;22:19–29.
  • Amon I, Amon K, Franke G, Mohr C. Pharmacokinetics of metronidazole in pregnant-women. Chemotherapy 1981;27:73–79.
  • Hytten FE, Leitch I. The physiology of human pregnancy. Oxford: Brackwell Scientific Publications; 1971.
  • Bergan T, Arnold E. Pharmacokinetics of metronidazole in healthy adult volunteers after tablets and suppositories. Chemotherapy 1980;26:231–241.
  • Houghton GW, Thorne PS, Smith J, Templeton R, Collier J. Comparison of the pharmacokinetics of metronidazole in healthy female volunteers following either a single oral or intravenous dose. Br J Clin Pharmacol 1979;8:337–341.
  • Loft S, Døssing M, Poulsen HE, Sonne J, Olesen KL, Simonsen K, Andreasen PB. Influence of dose and route of administration on disposition of metronidazole and its major metabolites. Eur J Clin Pharmacol 1986;30:467–473.
  • Hill GB. The microbiology of bacterial vaginosis. Am J Obstet Gynecol 1993;169:450–454.
  • Hillier SL. Diagnostic microbiology of bacterial vaginosis. Am J Obstet Gynecol 1993;169:455–459.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.