Expression levels of cyclooxygenase-2, tumor necrosis factor-α and inducible NO synthase in placental tissue of normal and preeclamptic pregnancies

References

• Dekker GA, van Geijn HP. Endothelial dysfunction in preeclampsia. I: Primary prevention; therapeutic perspectives. J Perinat Med 1996;24:119–139.
   PubMed Web of Science ®Google Scholar
• Brosens I, Robertson WB, Dixon HG. The physiological response of the vessels of the placental bed to normal pregnancy. J Pathol Bacteriol 1967;93:569–579.
   PubMedGoogle Scholar
• Pijnenborg R, Bland JM, Robertson WB, Brosens I. Uteroplacental arterial changes related to interstitial trophoblast migration in early human pregnancy. Placenta 1983;4:397–413.
   PubMed Web of Science ®Google Scholar
• Nasiell J, Nisell H, Blanck A, Lunell NO, Faxén M. Placental expression of endothelial constitutive nitric oxide synthase mRNA in pregnancy complicated by preeclampsia. Acta Obstet Gynecol Scand 1998;77:492–496.
   PubMedGoogle Scholar
• Papageorghiou AT, Yu CK, Bindra R, Pandis G, Nicolaides KH; Fetal Medicine Foundation Second Trimester Screening Group. Multicenter screening for pre-eclampsia and fetal growth restriction by transvaginal uterine artery Doppler at 23 weeks of gestation. Ultrasound Obstet Gynecol 2001;18:441–449.
   PubMed Web of Science ®Google Scholar
• Papageorghiou AT, Yu CK, Cicero S, Bower S, Nicolaides KH. Second-trimester uterine artery Doppler screening in unselected populations: a review. J Matern Fetal Neonatal Med 2002;12:78–88.
   PubMedGoogle Scholar
• Di Paolo S, Volpe P, Grandaliano G, Stallone G, Schena A, Greco P, Resta L, et al. Increased placental expression of tissue factor is associated with abnormal uterine and umbilical Doppler waveforms in severe preeclampsia with fetal growth restriction. J Nephrol 2003;16:650–657.
   PubMed Web of Science ®Google Scholar
• Pijnenborg R, Anthony J, Davey DA, Rees A, Tiltman A, Vercruysse L, van Assche A. Placental bed spiral arteries in the hypertensive disorders of pregnancy. Br J Obstet Gynaecol 1991;98:648–655.
   PubMedGoogle Scholar
• Myatt L, Miodovnik M. Prediction of preeclampsia. Semin Perinatol 1999;23:45–57.
   PubMed Web of Science ®Google Scholar
• Ylikorkala O, Viinikka L. The role of prostaglandins in obstetrical disorders. Baillieres Clin Obstet Gynaecol 1992;6:809–827.
   PubMedGoogle Scholar
• Marshall PJ, Kulmacz RJ, Lands WE. Constraints on prostaglandin biosynthesis in tissues. J Biol Chem 1987;262:3510–3517.
   PubMed Web of Science ®Google Scholar
• Appleby SB, Ristimäki A, Neilson K, Narko K, Hla T. Structure of the human cyclo-oxygenase-2 gene. Biochem J 1994;302 (Pt 3):723–727.
   PubMedGoogle Scholar
• Hla T, Neilson K. Human cyclooxygenase-2 cDNA. Proc Natl Acad Sci USA 1992;89:7384–7388.
   PubMed Web of Science ®Google Scholar
• Saito S, Ibaraki T, Enomoto M, Ichijo M, Motoyoshi K. Macrophage colony-stimulating factor induces the growth and differentiation of normal pregnancy human cytotrophoblast cells and hydatidiform moles but does not induce the growth and differentiation of choriocarcinoma cells. Jpn J Cancer Res 1994;85:245–252.
   PubMedGoogle Scholar
• Hunt JS, Soares MJ, Lei MG, Smith RN, Wheaton D, Atherton RA, Morrison DC. Products of lipopolysaccharide-activated macrophages (tumor necrosis factor-alpha, transforming growth factor-beta) but not lipopolysaccharide modify DNA synthesis by rat trophoblast cells exhibiting the 80-kDa lipopolysaccharide-binding protein. J Immunol 1989;143:1606–1613.
   PubMedGoogle Scholar
• Kupferminc MJ, Peaceman AM, Wigton TR, Rehnberg KA, Socol ML. Tumor necrosis factor-alpha is elevated in plasma and amniotic fluid of patients with severe preeclampsia. Am J Obstet Gynecol 1994;170:1752–7; discussion 1757.
   PubMedGoogle Scholar
• Conrad KP, Miles TM, Benyo DF. Circulating levels of immunoreactive cytokines in women with preeclampsia. Am J Reprod Immunol 1998;40:102–111.
   PubMed Web of Science ®Google Scholar
• Nasiell J, Nisell H, Blanck A, Lunell NO, Faxen M. Placental expression of endothelial constitutive nitric oxide synthase mRNA in pregnancy complicated by preeclampsia. Acta Obstet Gynecol Scand 1998;77:492–496.
   PubMedGoogle Scholar
• Izumi H, Makino Y, Shirakawa K, Garfield RE. Role of nitric oxide on vasorelaxation in human umbilical artery. Am J Obstet Gynecol 1995;172:1477–1484.
   PubMed Web of Science ®Google Scholar
• Buhimschi I, Yallampalli C, Dong YL, Garfield RE. Involvement of a nitric oxide-cyclic guanosine monophosphate pathway in control of human uterine contractility during pregnancy. Am J Obstet Gynecol 1995;172:1577–1584.
   PubMed Web of Science ®Google Scholar
• Lyall F, Greer IA, Young A, Myatt L. Nitric oxide concentrations are increased in the feto-placental circulation in intrauterine growth restriction. Placenta 1996;17:165–168.
   PubMed Web of Science ®Google Scholar
• Lyall F, Young A, Greer IA. Nitric oxide concentrations are increased in the fetoplacental circulation in preeclampsia. Am J Obstet Gynecol 1995;173:714–718.
   PubMed Web of Science ®Google Scholar
• Purcell TL, Buhimschi IA, Given R, Chwalisz K, Garfield RE. Inducible nitric oxide synthase is present in the rat placenta at the fetal-maternal interface and decreases prior to labour. Mol Hum Reprod 1997;3:485–491.
   PubMed Web of Science ®Google Scholar
• Sun WH, Sun YL, Fang RN, Shao Y, Xu HC, Xue QP, Ding GX, Cheng YL. Expression of cyclooxygenase-2 and matrix metalloproteinase-9 in gastric carcinoma and its correlation with angiogenesis. Jpn J Clin Oncol 2005;35:707–713.
   PubMedGoogle Scholar
• Tokyol C, Aktepe F, Dilek FH, Sahin O, Arioz DT. Expression of cyclooxygenase-2 and matrix metalloproteinase-2 in adenomyosis and endometrial polyps and its correlation with angiogenesis. Int J Gynecol Pathol 2009;28:148–156.
   PubMedGoogle Scholar
• Robinson JS, Redman CW, Clover L, Mitchell MD. The concentrations of the prostaglandins E and F, 13 14-dihydro-15-oxo-prostaglandin F and thromboxane B2. In tissues obtained from women with and without pre-eclampsia. Prostaglandins Med 1979;3:223–234.
   PubMedGoogle Scholar
• Johnson RD, Walsh SW, Everson WV, Nelson DM. Differentiation and growth on a fibrin matrix modulate the cyclooxygenase expression and thromboxane production by cultured human placental trophoblasts. Prostaglandins Leukot Essent Fatty Acids 1995;52:21–27.
   PubMedGoogle Scholar
• Wetzka B, Nüsing R, Charnock-Jones DS, Schäfer W, Zahradnik HP, Smith SK. Cyclooxygenase-1 and -2 in human placenta and placental bed after normal and pre-eclamptic pregnancies. Hum Reprod 1997;12:2313–2320.
   PubMedGoogle Scholar
• Khan I, al-Yatama M, Nandakumaran M. Expression of the Na(+)-H+ exchanger isoform-1 and cyclooxygenases in human placentas: their implications in preeclampsia. Biochem Mol Biol Int 1999;47:715–722.
   PubMedGoogle Scholar
• Börekçi B, Aksoy H, Toker A, Ozkan A. Placental tissue cyclo-oxygenase 1 and 2 in pre-eclamptic and normal pregnancy. Int J Gynaecol Obstet 2006;95:127–131.
   PubMedGoogle Scholar
• Beinder E, Mohaupt MG, Schlembach D, Fischer T, Sterzel RB, Lang N, Baylis C. Nitric oxide synthase activity and Doppler parameters in the fetoplacental and uteroplacental circulation in preeclampsia. Hypertens Pregnancy 1999;18:115–127.
   PubMed Web of Science ®Google Scholar
• Napolitano M, Miceli F, Calce A, Vacca A, Gulino A, Apa R, Lanzone A. Expression and relationship between endothelin-1 messenger ribonucleic acid (mRNA) and inducible/endothelial nitric oxide synthase mRNA isoforms from normal and preeclamptic placentas. J Clin Endocrinol Metab 2000;85:2318–2323.
   PubMed Web of Science ®Google Scholar
• Schiessl B, Mylonas I, Hantschmann P, Kuhn C, Schulze S, Kunze S, Friese K, Jeschke U. Expression of endothelial NO synthase, inducible NO synthase, and estrogen receptors alpha and beta in placental tissue of normal, preeclamptic, and intrauterine growth-restricted pregnancies. J Histochem Cytochem 2005;53:1441–1449.
   PubMed Web of Science ®Google Scholar
• Lyall F, Jablonka-Shariff A, Johnson RD, Olson LM, Nelson DM. Gene expression of nitric oxide synthase in cultured human term placental trophoblast during in vitro differentiation. Placenta 1998;19:253–260.
   PubMed Web of Science ®Google Scholar
• Myatt L, Eis AL, Brockman DE, Kossenjans W, Greer I, Lyall F. Inducible (type II) nitric oxide synthase in human placental villous tissue of normotensive, pre-eclamptic and intrauterine growth-restricted pregnancies. Placenta 1997;18:261–268.
   PubMed Web of Science ®Google Scholar
• Garvey EP, Tuttle JV, Covington K, Merrill BM, Wood ER, Baylis SA, Charles IG. Purification and characterization of the constitutive nitric oxide synthase from human placenta. Arch Biochem Biophys 1994;311:235–241.
   PubMed Web of Science ®Google Scholar
• Myatt L, Brewer AS, Langdon G, Brockman DE. Attenuation of the vasoconstrictor effects of thromboxane and endothelin by nitric oxide in the human fetal-placental circulation. Am J Obstet Gynecol 1992;166:224–230.
   PubMed Web of Science ®Google Scholar
• Myatt L, Brewer A, Brockman DE. The action of nitric oxide in the perfused human fetal-placental circulation. Am J Obstet Gynecol 1991;164:687–692.
   PubMed Web of Science ®Google Scholar
• Ramsay B, De Belder A, Campbell S, Moncada S, Martin JF. A nitric oxide donor improves uterine artery diastolic blood flow in normal early pregnancy and in women at high risk of pre-eclampsia. Eur J Clin Invest 1994;24:76–78.
   PubMed Web of Science ®Google Scholar
• Giles W, O’Callaghan S, Boura A, Walters W. Reduction in human fetal umbilical-placental vascular resistance by glyceryl trinitrate. Lancet 1992;340:856.
   PubMed Web of Science ®Google Scholar
• Szewczyk G, Szukiewicz D, Smiertka W, Szewczyk A. [Mast cells as a source of nitric oxide in the human placenta–morphometric analysis in preeclampsia complicated pregnancy]. Ginekol Pol 2005;76:720–726.
   PubMedGoogle Scholar
• Sharma D, Singh A, Trivedi SS, Bhattacharjee J. Role of endothelin and inflammatory cytokines in pre-eclampsia - A pilot North Indian study. Am J Reprod Immunol 2011;65:428–432.
   PubMed Web of Science ®Google Scholar
• Tsukimori K, Komatsu H, Fukushima K, Kaku T, Nakano H, Wake N. Inhibition of nitric oxide synthetase at mid-gestation in rats is associated with increases in arterial pressure, serum tumor necrosis factor-alpha, and placental apoptosis. Am J Hypertens 2008;21:477–481.
   PubMed Web of Science ®Google Scholar
• Benyo DF, Smarason A, Redman CW, Sims C, Conrad KP. Expression of inflammatory cytokines in placentas from women with preeclampsia. J Clin Endocrinol Metab 2001;86:2505–2512.
   PubMed Web of Science ®Google Scholar
• Hayashi M, Ueda Y, Yamaguchi T, Sohma R, Shibazaki M, Ohkura T, Inaba N. Tumor necrosis factor-alpha in the placenta is not elevated in pre-eclamptic patients despite its elevation in peripheral blood. Am J Reprod Immunol 2005;53:113–119.
   PubMed Web of Science ®Google Scholar
• Pijnenborg R, McLaughlin PJ, Vercruysse L, Hanssens M, Johnson PM, Keith JC Jr, Van Assche FA. Immunolocalization of tumour necrosis factor-alpha (TNF-alpha) in the placental bed of normotensive and hypertensive human pregnancies. Placenta 1998;19:231–239.
   PubMed Web of Science ®Google Scholar